(Q39634508)

13 September 2017

title

SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis (English)

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13 September 2017

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Yanze Li

1

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13 September 2017

Haruka Matsumori

2

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13 September 2017

Yuji Nakayama

3

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13 September 2017

Mitsuhiko Osaki

4

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13 September 2017

Hirotada Kojima

5

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13 September 2017

Akihiro Kurimasa

6

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13 September 2017

Hisao Ito

7

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13 September 2017

Seiichi Mori

8

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13 September 2017

Motonobu Katoh

9

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13 September 2017

Mitsuo Oshimura

10

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13 September 2017

Toshiaki Inoue

11

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13 September 2017

publication date

9 November 2010

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13 September 2017

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13 September 2017

volume

16

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13 September 2017

issue

1

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13 September 2017

page(s)

34-45

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Human histone deacetylase SIRT2 interacts with the homeobox transcription factor HOXA10

13 September 2017

cites work

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https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

The SIRT2 deacetylase regulates autoacetylation of p300

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

Inactivation of p53 in normal human cells increases G2/M arrest and sensitivity to DNA-damaging agents

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

Tissue-specific regulation of SIRT1 by calorie restriction

21 January 2018

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Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

Aging and disease: connections to sirtuins

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

Polyubiquitination of p53 by a ubiquitin ligase activity of p300.

21 January 2018

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Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction

21 January 2018

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Acetylation of Sirt2 by p300 attenuates its deacetylase activity

21 January 2018

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Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes

21 January 2018

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p53 antisense oligonucleotide inhibits growth of human colon tumor and normal cell lines.

21 January 2018

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The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation

21 January 2018

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SIRT2, a tubulin deacetylase, acts to block the entry to chromosome condensation in response to mitotic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

SIRT2 downregulation confers resistance to microtubule inhibitors by prolonging chronic mitotic arrest

21 January 2018

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Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect.

21 January 2018

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Negative control of p53 by Sir2alpha promotes cell survival under stress

21 January 2018

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Role of NAD-dependent deacetylases SIRT1 and SIRT2 in radiation and cisplatin-induced cell death in vertebrate cells.

21 January 2018

1 reference

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Loss of centrosome integrity induces p38-p53-p21-dependent G1-S arrest

21 January 2018

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The Sirtuin family: therapeutic targets to treat diseases of aging

21 January 2018

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Activating p38 MAPK: new tricks for an old kinase.

21 January 2018

1 reference

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Mutations in SIRT2 deacetylase which regulate enzymatic activity but not its interaction with HDAC6 and tubulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

Clonal heterogeneity in differentiation potential of immortalized human mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

Proteasome-mediated degradation of the coactivator p300 impairs cardiac transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

The acetylase activity of p300 is dispensable for MDM2 stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2443.2010.01460.X

10.1111/J.1365-2443.2010.01460.X

21 January 2018

Identifiers

DOI

1 reference

13 September 2017

1 reference