(Q39639196)

13 September 2017

title

Effects of specific DNMT gene depletion on cancer cell transformation and breast cancer cell invasion; toward selective DNMT inhibitors (English)

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13 September 2017

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Flora Chik

1

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13 September 2017

Moshe Szyf

series ordinal

2

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13 September 2017

language of work or name

English

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publication date

27 October 2010

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13 September 2017

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13 September 2017

volume

32

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13 September 2017

issue

2

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13 September 2017

page(s)

224-232

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Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

13 September 2017

cites work

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

DNA methylation in cancer: too much, but also too little

21 January 2018

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Allosteric Activator Domain of Maintenance Human DNA (Cytosine-5) Methyltransferase and Its Role in Methylation Spreading

21 January 2018

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Transcription of mouse DNA methyltransferase 1 (Dnmt1) is regulated by both E2F-Rb-HDAC-dependent and -independent pathways

21 January 2018

1 reference

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AUF1 cell cycle variations define genomic DNA methylation by regulation of DNMT1 mRNA stability

21 January 2018

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Regulation of DNA methylation by the Ras signaling pathway

21 January 2018

1 reference

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A conserved 3'-untranslated element mediates growth regulation of DNA methyltransferase 1 and inhibits its transforming activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

DNA methyltransferase is a downstream effector of cellular transformation triggered by simian virus 40 large T antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells.

21 January 2018

1 reference

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Suppression of intestinal neoplasia by DNA hypomethylation.

21 January 2018

1 reference

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Expression of antisense to DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesis

21 January 2018

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Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide

21 January 2018

1 reference

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Identification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

DNA hypomethylation leads to elevated mutation rates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice.

21 January 2018

1 reference

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Induction of Tumors in Mice by Genomic Hypomethylation

21 January 2018

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Cellular differentiation, cytidine analogs and DNA methylation

21 January 2018

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Current status of epigenetic treatment in myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

Role of promoter methylation in regulation of the mammalian heparanase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

Demethylation of urokinase promoter as a prognostic marker in patients with breast carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

Methylation status of uPA promoter as a molecular mechanism regulating prostate cancer invasion and growth in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

Inhibition of DNA methyltransferase inhibits DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

Epigenetic programming by maternal behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

Expression of DNA (5-cytosin)-methyltransferases (DNMTs) in hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

DNA methyltransferase inhibition induces the transcription of the tumor suppressor p21(WAF1/CIP1/sdi1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

Epigenomic stress response. Knockdown of DNA methyltransferase 1 triggers an intra-S-phase arrest of DNA replication and induction of stress response genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

DNA methyltransferase 1 knockdown activates a replication stress checkpoint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGQ221

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGQ221

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13 September 2017

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