(Q39640387)

13 September 2017

title

Inhibition of p53 induces invasion of serous borderline ovarian tumor cells by accentuating PI3K/Akt-mediated suppression of E-cadherin (English)

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13 September 2017

J-C Cheng

1

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13 September 2017

N Auersperg

series ordinal

2

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13 September 2017

P C K Leung

series ordinal

3

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13 September 2017

language of work or name

English

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publication date

25 October 2010

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13 September 2017

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13 September 2017

volume

30

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13 September 2017

issue

9

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13 September 2017

page(s)

1020-1031

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Rb depletion results in deregulation of E-cadherin and induction of cellular phenotypic changes that are characteristic of the epithelial-to-mesenchymal transition.

13 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Mechanisms underlying p53 regulation of PIK3CA transcription in ovarian surface epithelium and in ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Expression profiling of serous low malignant potential, low-grade, and high-grade tumors of the ovary.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Expression of cadherins in benign, borderline, and malignant ovarian epithelial tumors: a clinicopathologic study of 60 cases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

PI3K/Akt signalling pathway and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Enumeration of the simian virus 40 early region elements necessary for human cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Molecular requirements for epithelial-mesenchymal transition during tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3' kinase/AKT pathways

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.486

The epithelial-mesenchymal transition: new insights in signaling, development, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Inactivation of the mitogen-activated protein kinase pathway as a potential target-based therapy in ovarian serous tumors with KRAS or BRAF mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Gain of oncogenic function of p53 mutants regulates E-cadherin expression uncoupled from cell invasion in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Phosphatidylinositol 3-kinases in tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

High frequency of mutations of the PIK3CA gene in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

21 January 2018

TP53 and ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

PIK3CA is implicated as an oncogene in ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Molecular pathogenesis of ovarian borderline tumors: new insights and old challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Patterns of p53 mutations separate ovarian serous borderline tumors and low- and high-grade carcinomas and provide support for a new model of ovarian carcinogenesis: a mutational analysis with immunohistochemical correlation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

An improved assay to quantitate the invasiveness of cells in modified Boyden chambers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

SV40 early genes induce neoplastic properties in serous borderline ovarian tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Serous borderline ovarian tumors in long-term culture: phenotypic and genotypic distinction from invasive ovarian carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Mutation of the PIK3CA gene in ovarian and breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Serous borderline tumors of the ovary with noninvasive peritoneal implants

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Mutations of BRAF and KRAS precede the development of ovarian serous borderline tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Early recurrence of ovarian serous borderline tumor as high-grade carcinoma: a report of two cases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

Differential expression of the cell-cell adhesion molecule E-cadherin in ascites and solid human ovarian tumor cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.486

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.486

1 reference

13 September 2017

1 reference