(Q39645208)

13 September 2017

1 reference

title

Biosynthesis and biotransformation of glutathione S-conjugates to toxic metabolites (English)

1 reference

13 September 2017

1 reference

Anders MW

1

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13 September 2017

Lash L

2

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13 September 2017

Dekant W

3

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13 September 2017

Elfarra AA

4

1 reference

13 September 2017

Dohn DR

5

1 reference

13 September 2017

language of work or name

English

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publication date

1 January 1988

1 reference

Critical Reviews in Toxicology

13 September 2017

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13 September 2017

18

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13 September 2017

311-341

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13 September 2017

4

1 reference

The mutagenic effect of 1,2-dichloroethane on Salmonella typhimurium I. Activation through conjugation with glutathion in vitro

13 September 2017

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

S-[2-(N7-guanyl)ethyl]glutathione, the major DNA adduct formed from 1,2-dibromoethane.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Cellular effects of reactive intermediates: nephrotoxicity of S-conjugates of amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Glutathione transferases: nomenclature.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Glutathione transferases: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

The metabolism and nephrotoxicity of tetrafluoroethylene in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

The metabolism and disposition of hexachloro-1:3-butadiene in the rat and its relevance to nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Identification of S-1,2-dichlorovinyl-N-acetyl-cysteine as a urinary metabolite of trichloroethylene: a possible explanation for its nephrocarcinogenicity in male rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

In vitro activation of 1,2-dichloroethane by microsomal and cytosolic enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Glutathione- and cysteine-mediated cytotoxicity of allyl and benzyl isothiocyanate.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

The metabolism of benzyl isothiocyanate and its cysteine conjugate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Glutathione S-conjugate formation from 1-chloro-2,4-dinitrobenzene and biliary S-conjugate excretion in the perfused rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Intrahepatic transport and utilization of biliary glutathione and its metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Inhibition of gamma-glutamyl transpeptidase and induction of glutathionuria by gamma-glutamyl amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Role for an episulfonium ion in S-(2-chloroethyl)-DL-cysteine-induced cytotoxicity and its reaction with glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

The formation and biotransformation of cysteine conjugates of halogenated ethylenes by rabbit renal tubules

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Structure/activity studies of the nephrotoxic and mutagenic action of cysteine conjugates of chloro- and fluoroalkenes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Metabolic activation and detoxication of nephrotoxic cysteine and homocysteine S-conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Purification and characterization of human hepatic cysteine-conjugate beta-lyase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Bacterial beta-lyase mediated cleavage and mutagenicity of cysteine conjugates derived from the nephrocarcinogenic alkenes trichloroethylene, tetrachloroethylene and hexachlorobutadiene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

S-(1,2-dichlorovinyl)-L-homocysteine-induced cytotoxicity in isolated rat kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

The metabolism of S-(1,2 Dichlorovinyl)-l-cysteine by rat liver mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

A critical review of the literature on hydrogen sulfide toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Metabolism of S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine to hydrogen sulfide and the role of hydrogen sulfide in S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine-induced mitochondrial toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Bioactivation mechanism of the cytotoxic and nephrotoxic S-conjugate S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Use of isolated kidney cells for study of drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Formation and metabolism of a glutathione-S-conjugate in isolated rat liver and kidney cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

The mechanism of pentachlorobutadienyl-glutathione nephrotoxicity studied with isolated rat renal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Coupling of active ion transport and aerobic respiratory rate in isolated renal tubules

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Calmodulin Plays a Pivotal Role in Cellular Regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Regulation of intracellular calcium compartmentation: studies with isolated hepatocytes and t-butyl hydroperoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Calcium Dependence of Toxic Cell Death: A Final Common Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Toxic Injury to Isolated Hepatocytes Is Not Dependent on Extracellular Calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Effect of halogenated vinyl cysteine conjugates on renal tubular active transport

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Effect of the organic acid transport inhibitor probenecid on renal cortical uptake and proximal tubular toxicity of hexachloro-1,3-butadiene and its conjugates.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Allyl alcohol toxicity in isolated renal epithelial cells: protective effects of low molecular weight thiols.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Further studies on the site and mechanism of action of s-(1,2 dichlorovinyl)-l-systeine and s-(1,2 dichlorovinyl)-3-mercaptopropionic acid in rat liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Glutathione depletion by phorone organ specificity and effect on hepatic microsomal mixed-function oxidase system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Distribution of cysteine conjugate beta-lyase in gastrointestinal bacteria and in the environment.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Purification of soluble and mitochondrial glutamine transaminase K from rat kidney. Use of a sensitive assay involving transamination between L-phenylalanine and alpha-keto-gamma-methiolbutyrate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

The role of glutathione conjugation in the mutagenicity of 1,2-dibromoethane.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Mutagenic activity of various chemicals in Salmonella strain TA100 and glutathione-deficient derivatives. On the role of glutathione in the detoxification or activation of mutagens inside bacterial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

The mutagenic effect of 1,2-dichloroethane on Salmonella typhimurium. II. activation by the isolated perfused rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Stereoselective activation of vicinal dihalogen compounds to mutagens by glutathione conjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Interactions of S-(2-haloethyl)-mercapturic acid analogs with plasmid DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Glutathione-mediated binding of dibromoalkanes to DNA: specificity of rat glutathione-S-transferases and dibromoalkane structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

The bioactivation of 1,2-dibromoethane in rat hepatocytes: covalent binding to nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Deuterium isotope effect on the metabolism and toxicity of 1,2-dibromoethane

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Mutagenicity of the mercapturic acid and other S-containing derivatives of hexachloro-1,3-butadiene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Mercapturic acid formation is an activation and intermediary step in the metabolism of hexachlorobutadiene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Genotoxic and mutagenic assays of halothane metabolites in bacillus subtilis and salmonella typhimurium

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Production of DNA single strand breaks in rabbit renal tissue after exposure to 1,2-dichlorovinylcysteine.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

Results of a two year chronic toxicity study with hexachlorobutadiene in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809037470

10.3109/10408448809037470

21 January 2018

Identifiers

DOI

0 references

1 reference