(Q39647429)

13 September 2017

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title

Clinical pharmacodynamics of anticancer drugs: a basis for extending the concept of dose-intensity (English)

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13 September 2017

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W E Evans

1

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13 September 2017

1 June 1988

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13 September 2017

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13 September 2017

56

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13 September 2017

6

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13 September 2017

241-248

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Childhood leukaemia: a relationship between intracellular 6-mercaptopurine metabolites and neutropenia

13 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF00320282

A dose and time response analysis of the treatment of Hodgkin's disease with MOPP chemotherapy

21 January 2018

1 reference

12 December 2020

Therapeutic drug monitoring in oncology. Problems and potential in antineoplastic therapy

1 reference

12 December 2020

Blood levels of chemotherapeutic agents and clinical outcome

1 reference

12 December 2020

Drug dosage and remission duration in childhood lymphocytic leukemia

1 reference

12 December 2020

Average relative dose intensity and the impact on design of clinical trials.

1 reference

12 December 2020

Methotrexate cerebrospinal fluid and serum concentrations after intermediate-dose methotrexate infusion

1 reference

12 December 2020

Pharmacokinetics of anticancer drugs in children

1 reference

12 December 2020

Pharmacokinetic parameters of 1-beta-D-arabinofuranosylcytosine (ara-C) and their relationship to intracellular metabolism of ara-C, toxicity, and response of patients with acute nonlymphocytic leukemia treated with conventional and high-dose ara-C

1 reference

12 December 2020

CLINICAL STUDIES OF DICHLOROMETHOTREXATE (NSC 29630)

1 reference

12 December 2020

Intensive chemotherapy of small cell bronchogenic carcinoma

1 reference

12 December 2020

Phase I clinical and pharmacological study of 72-hour continuous infusion of etoposide in patients with advanced cancer

1 reference

12 December 2020

Clinical pharmacodynamics of high-dose methotrexate in acute lymphocytic leukemia. Identification of a relation between concentration and effect

1 reference

12 December 2020

Methotrexate systemic clearance influences probability of relapse in children with standard-risk acute lymphocytic leukaemia

1 reference

12 December 2020

FURTHER COMPARATIVE TRIAL OF TRIETHYLENE THIOPHOSPHORAMIDE AND MECHLORETHAMINE IN PATIENTS WITH MELANOMA AND HODGKIN'S DISEASE

1 reference

12 December 2020

Analysis of dose intensity for adjuvant chemotherapy trials in stage II breast cancer

1 reference

12 December 2020

Prospective validation of a pharmacologically based dosing scheme for the cis-diamminedichloroplatinum(II) analogue diamminecyclobutanedicarboxylatoplatinum

1 reference

12 December 2020

Phase I clinical and pharmacokinetic study of hexamethylene bisacetamide (NSC 95580) administered as a five-day continuous infusion.

1 reference

12 December 2020

Clinical pharmacodynamics of continuous infusion teniposide: systemic exposure as a determinant of response in a phase I trial

1 reference

12 December 2020

Human pharmacokinetics, excretion, and metabolism of the anthracycline antibiotic menogaril (7-OMEN, NSC 269148) and their correlation with clinical toxicities

1 reference

12 December 2020

Variable bioavailability of oral mercaptopurine. Is maintenance chemotherapy in acute lymphoblastic leukemia being optimally delivered?

1 reference

12 December 2020

Clinical pharmacodynamic studies of high-dose methotrexate in acute lymphocytic leukemia

1 reference

12 December 2020

Systemic clearance of methotrexate in the prognosis of acute lymphoblastic leukemia in children

1 reference

12 December 2020

Dose: a critical factor in cancer chemotherapy

1 reference

12 December 2020

Prognostic importance of systemic clearance of methotrexate in childhood acute lymphoblastic leukemia

1 reference

12 December 2020

Dose-response effect of adjuvant chemotherapy in breast cancer

1 reference

12 December 2020

Can severe vincristine neurotoxicity be prevented?

1 reference

12 December 2020

Pharmacokinetics and dosage reduction of cis-diammine(1,1-cyclobutanedicarboxylato)platinum in patients with impaired renal function

1 reference

12 December 2020

Dose-response is alive and well

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00320282

1 reference

13 September 2017

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PubMed ID

3289632