(Q39647915)

English

TLR4 signaling is coupled to SRC family kinase activation, tyrosine phosphorylation of zonula adherens proteins, and opening of the paracellular pathway in human lung microvascular endothelia

scientific article published on 7 March 2008

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scholarly article

1 reference

Europe PubMed Central

13 September 2017

TLR4 signaling is coupled to SRC family kinase activation, tyrosine phosphorylation of zonula adherens proteins, and opening of the paracellular pathway in human lung microvascular endothelia (English)

1 reference

Europe PubMed Central

13 September 2017

toll-like receptor

0 references

phosphorylation

1 reference

based on heuristic

inferred from title

0 references

author name string

Ping Gong

1

1 reference

Europe PubMed Central

13 September 2017

Daniel J Angelini

2

1 reference

Europe PubMed Central

13 September 2017

Shiqi Yang

3

1 reference

Europe PubMed Central

13 September 2017

Guanjun Xia

4

1 reference

Europe PubMed Central

13 September 2017

Alan S Cross

5

1 reference

Europe PubMed Central

13 September 2017

Dean Mann

6

1 reference

Europe PubMed Central

13 September 2017

Douglas D Bannerman

7

1 reference

Europe PubMed Central

13 September 2017

Stefanie N Vogel

8

1 reference

Europe PubMed Central

13 September 2017

Simeon E Goldblum

9

1 reference

Europe PubMed Central

13 September 2017

language of work or name

0 references

publication date

7 March 2008

1 reference

Europe PubMed Central

13 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

13 September 2017

283

1 reference

Europe PubMed Central

13 September 2017

19

1 reference

Europe PubMed Central

13 September 2017

13437-13449

1 reference

Europe PubMed Central

13 September 2017

p120 catenin and phosphorylation: Mechanisms and traits of an unresolved issue.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

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Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling

1 reference

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TRAF6 activation of PI 3-kinase-dependent cytoskeletal changes is cooperative with Ras and is mediated by an interaction with cytoplasmic Src.

1 reference

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14 September 2017

Lipopolysaccharide signaling in endothelial cells

1 reference

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Interleukin-1beta induced vascular permeability is dependent on induction of endothelial tissue factor (TF) activity

1 reference

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Inhibition of SRC tyrosine kinases suppresses activation of nuclear factor-kappa B, and serine and tyrosine phosphorylation of Ikappa B-alpha in lipopolysaccharide-stimulated RAW 264.7 macrophages

1 reference

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14 September 2017

Receptor protein tyrosine phosphatase micro regulates the paracellular pathway in human lung microvascular endothelia

1 reference

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Structure and regulation of Src family kinases

1 reference

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Tumor necrosis factor alpha-converting enzyme mediates MUC5AC mucin expression in cultured human airway epithelial cells

1 reference

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Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production

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The epidemiology of sepsis in the United States from 1979 through 2000

1 reference

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Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs

1 reference

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p120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction

1 reference

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Toll-like receptor-mediated tyrosine phosphorylation of paxillin via MyD88-dependent and -independent pathways

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CD14 signalling in lipid rafts: new ligands and co-receptors

1 reference

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Activation of the RON receptor tyrosine kinase by macrophage-stimulating protein inhibits inducible cyclooxygenase-2 expression in murine macrophages

1 reference

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Turn-off, drop-out: functional state switching of cadherins

1 reference

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14 September 2017

Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells

1 reference

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The hunting of the Src

1 reference

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14 September 2017

Synthesis and surface expression of CD14 by human endothelial cells

1 reference

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14 September 2017

SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Thrombin signalling and protease-activated receptors

1 reference

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14 September 2017

Endothelium function in sepsis

1 reference

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14 September 2017

Synergistic action of pro-inflammatory agents: cellular and molecular aspects.

1 reference

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14 September 2017

Direct effects of endotoxin on the endothelium: barrier function and injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

In vivo association of pp60v-src and the gap-junction protein connexin 43 in v-src-transformed fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Thrombospondin-1 induces tyrosine phosphorylation of adherens junction proteins and regulates an endothelial paracellular pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Endotoxin-neutralizing protein protects against endotoxin-induced endothelial barrier dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Cell confluence regulates tyrosine phosphorylation of adherens junction components in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Effects of tyrphostins and genistein on the circulatory failure and organ dysfunction caused by endotoxin in the rat: a possible role for protein tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Platelet endothelial cell adhesion molecule-1 is phosphorylatable by c-Src, binds Src-Src homology 2 domain, and exhibits immunoreceptor tyrosine-based activation motif-like properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

LPS and Taxol activate Lyn kinase autophosphorylation in Lps(n), but not in Lpsd), macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Gram-negative sepsis: a dilemma of modern medicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

src‐related protein tyrosine kinases are physically associated with the surface antigen CD36 in human dermal microvascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Endotoxinemia and thrombocytopenia during neonatal necrotizing enterocolitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Endotoxin and lung injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Mediation systems in bacterial lipopolysaccharide-induced hypotension and disseminated intravascular coagulation. I. The role of complement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Role of TLR4 tyrosine phosphorylation in signal transduction and endotoxin tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

TNF-alpha increases tyrosine phosphorylation of vascular endothelial cadherin and opens the paracellular pathway through fyn activation in human lung endothelia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Response of human pulmonary epithelial cells to lipopolysaccharide involves Toll-like receptor 4 (TLR4)-dependent signaling pathways: evidence for an intracellular compartmentalization of TLR4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor kappaB activation by Toll-like receptor 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

TRAF6 and C-SRC induce synergistic AP-1 activation via PI3-kinase-AKT-JNK pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-kappa B signaling pathway components

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Role for circulating lipoproteins in protection from endotoxin toxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Endothelial cell-to-cell junctions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

14 September 2017

Toll-like receptor 1 inhibits Toll-like receptor 4 signaling in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

25 September 2017

Novel approaches to the treatment of sepsis: lessons learned and future directions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

25 September 2017

Knockouts of Src-family kinases: stiff bones, wimpy T cells, and bad memories.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

25 September 2017

Tyrosine phosphorylation of connexin 43 by v-Src is mediated by SH2 and SH3 domain interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

25 September 2017

Transient venular permeability increase and endothelial gap formation induced by histamine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

25 September 2017

Bacterial lipopolysaccharide activates NF-kappaB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

15 June 2018

Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

15 June 2018

Endotoxin-induced migration of monocytes and PECAM-1 phosphorylation are abrogated by PAF receptor antagonists.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

15 June 2018

Interendothelial junctions: structure, signalling and functional roles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

15 June 2018

Effects of Different Types and Combinations of Antimicrobial Agents on Endotoxin Release from Gram-negative Bacteria: An In-Vitro and In-Vivo Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

15 June 2018

CD14 contributes to the adherence of human monocytes to cytokine-stimulated endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

15 June 2018

Soluble CD14 participates in the response of cells to lipopolysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

15 June 2018

Chemical, physical, biological properties of a lipopolysaccharide from Escherichia coli K-235.

1 reference

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17 June 2018

Specific phosphorylation of p120-catenin regulatory domain differently modulates its binding to RhoA.

1 reference

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21 August 2018

Src kinase phosphorylates vascular endothelial-cadherin in response to vascular endothelial growth factor: identification of tyrosine 685 as the unique target site.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

21 August 2018

Inhibition of the Src and Jak kinases protects against lipopolysaccharide-induced acute lung injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

21 August 2018

TLR4 is the signaling but not the lipopolysaccharide uptake receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

21 August 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

21 August 2018

CD40-mediated activation of vascular smooth muscle cell chemokine production through a Src-initiated, MAPK-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

21 August 2018

PAF- and bradykinin-induced hyperpermeability of rat venules is independent of actin-myosin contraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

21 August 2018

Lipopolysaccharide-induced reductions in cellular coupling correlate with tyrosine phosphorylation of connexin 43.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

21 August 2018

Genistein prevents nuclear factor-kappa B activation and acute lung injury induced by lipopolysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

21 August 2018

Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

21 August 2018

The p120 catenin family: complex roles in adhesion, signaling and cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

21 August 2018

Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

21 August 2018

Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

21 August 2018

Endotoxin induces endothelial barrier dysfunction through protein tyrosine phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

21 August 2018

Bacterial lipopolysaccharide induces actin reorganization, intercellular gap formation, and endothelial barrier dysfunction in pulmonary vascular endothelial cells: concurrent F-actin depolymerization and new actin synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

21 August 2018

Antibiotic-induced endotoxin release in patients with gram-negative urosepsis: a double-blind study comparing imipenem and ceftazidime.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

21 August 2018

Lipopolysaccharide (LPS) signal transduction and clearance. Dual roles for LPS binding protein and membrane CD14.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442341

21 August 2018

Plasma endotoxin as a predictor of multiple organ failure and death in systemic meningococcal disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707986200

21 January 2018

Expression of Syk is associated with nasal polyp in patients with allergic rhinitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18326860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Src family tyrosine kinases prevents lipopolysaccharide-induced hyporeactivity in isolated rat tail arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/18326860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-CD14 antibodies reduce responses of cultured human endothelial cells to endotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18326860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histamine induces tyrosine phosphorylation of endothelial cell-to-cell adherens junctions

1 reference

https://pubmed.ncbi.nlm.nih.gov/18326860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of hemostasis alterations in sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18326860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The counteradhesive protein SPARC regulates an endothelial paracellular pathway through protein tyrosine phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18326860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of src-family tyrosine kinases by LPS regulates cytokine production in dendritic cells by controlling AP-1 formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18326860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The non-receptor tyrosine kinase Lyn is localised in the developing murine blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/18326860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergy of lipopolysaccharide and inflammatory cytokines in murine pregnancy: alloimmunization prevents abortion but does not affect the induction of preterm delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/18326860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M707986200

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

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