(Q39656631)

13 September 2017

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title

Variability in drug metabolism: importance of genetic constitution (English)

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13 September 2017

Schellens JH

1

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13 September 2017

Breimer DD

series ordinal

2

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13 September 2017

publication date

1 April 1987

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Pharmaceutisch weekblad. Scientific edition

13 September 2017

published in

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13 September 2017

volume

9

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13 September 2017

issue

2

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13 September 2017

page(s)

85-90

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Polymorphic drug oxidation: pharmacokinetic basis and comparison of experimental indices

13 September 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF01960741

Metoprolol metabolism and debrisoquine oxidation polymorphism--population and family studies

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF01960741

Inter-ethnic difference in sparteine oxidation among Ghanaians and Germans

21 January 2018

1 reference

12 December 2020

Debrisoquine polymorphism and the metabolism and action of metoprolol, timolol, propranolol and atenolol

1 reference

12 December 2020

Human liver microsomal cytochrome P-450 mephenytoin 4-hydroxylase, a prototype of genetic polymorphism in oxidative drug metabolism. Purification and characterization of two similar forms involved in the reaction

1 reference

12 December 2020

Metoprolol and debrisoquin metabolism in Nigerians: lack of evidence for polymorphic oxidation

1 reference

12 December 2020

A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

1 reference

12 December 2020

The genetic polymorphism of sparteine metabolism

1 reference

12 December 2020

Characterization of a common genetic defect of cytochrome P-450 function (debrisoquine-sparteine type polymorphism)--increased Michaelis is Constant (Km) and loss of stereoselectivity of bufuralol 1'-hydroxylation in poor metabolizers

1 reference

12 December 2020

Pharmacogenetic covariation of defective N-oxidation of sparteine and 4-hydroxylation of debrisoquine

1 reference

12 December 2020

Stereoselective mephobarbital hydroxylation cosegregates with mephenytoin hydroxylation

1 reference

12 December 2020

Polymorphic hydroxylation of Debrisoquine in man.

1 reference

12 December 2020

Understanding the dose-effect relationship: clinical application of pharmacokinetic-pharmacodynamic models

1 reference

12 December 2020

Impairment of phenytoin parahydroxylation as a cause of severe intoxication

1 reference

12 December 2020

Ethnic differences in drug metabolism

1 reference

12 December 2020

The molecular mechanisms of two common polymorphisms of drug oxidation--evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation

1 reference

12 December 2020

Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man

1 reference

12 December 2020

Genetic control of isoniazid metabolism in man

1 reference

12 December 2020

Disease and Acetylation Polymorphism

1 reference

12 December 2020

Debrisoquine-type polymorphism of drug oxidation: purification from human liver of a cytochrome P450 isozyme with high activity for bufuralol hydroxylation

1 reference

12 December 2020

Defective oxidation of drugs: pharmacokinetic and therapeutic implications

1 reference

12 December 2020

N-acetylation pharmacogenetics

1 reference

12 December 2020

Defective N-oxidation of sparteine in man: A new pharmacogenetic defect

1 reference

12 December 2020

Isoniazid and ethionamide serum levels and inactivation in Finnish subjects

1 reference

12 December 2020

Variability in nifedipine pharmacokinetics and dynamics: a new oxidation polymorphism in man

1 reference

12 December 2020

Inheritance of phenytoin hypometabolism: a kinetic study of one family

1 reference

12 December 2020

Interindividual differences in drug oxidation: clinical importance.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF01960741

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13 September 2017

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