(Q39657956)

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A functional analysis of N-glycosylation-related genes on sialylation of recombinant erythropoietin in six commonly used mammalian cell lines.

scientific article published on 6 September 2010

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13 February 2020

A functional analysis of N-glycosylation-related genes on sialylation of recombinant erythropoietin in six commonly used mammalian cell lines (English)

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13 February 2020

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13 February 2020

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Peiqing Zhang

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13 February 2020

Diana Lifen Tan

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13 February 2020

Tianhua Wang

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13 February 2020

Mariati

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13 February 2020

Yuansheng Yang

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13 February 2020

Zhiwei Song

7

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13 February 2020

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6 September 2010

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13 February 2020

Metabolic Engineering

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13 February 2020

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13 February 2020

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13 February 2020

526-536

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13 February 2020

Essential and mutually compensatory roles of {alpha}-mannosidase II and {alpha}-mannosidase IIx in N-glycan processing in vivo in mice

1 reference

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On the frequency of protein glycosylation, as deduced from analysis of the SWISS-PROT database

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A new Chinese hamster ovary cell line expressing alpha2,6-sialyltransferase used as universal host for the production of human-like sialylated recombinant glycoproteins.

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The biosynthesis of highly branched N-glycans: studies on the sequential pathway and functional role of N-acetylglucosaminyltransferases I, II, III, IV, V and VI.

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Identification of essential amino acid residues in the hydrophilic loop regions of the CMP-sialic acid transporter and UDP-galactose transporter

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Effects of elevated ammonium on glycosylation gene expression in CHO cells

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Five Lec1 CHO cell mutants have distinct Mgat1 gene mutations that encode truncated N-acetylglucosaminyltransferase I.

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Modulation of circulatory residence of recombinant acetylcholinesterase through biochemical or genetic manipulation of sialylation levels

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A focused microarray approach to functional glycomics: transcriptional regulation of the glycome

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RCA-I-resistant CHO mutant cells have dysfunctional GnT I and expression of normal GnT I in these mutants enhances sialylation of recombinant erythropoietin

1 reference

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7 January 2021

Fluorometric assay of sialic acid in the picomole range: a modification of the thiobarbituric acid assay

1 reference

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7 January 2021

The human sialyltransferase family

1 reference

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7 January 2021

Intracellular functions of N-linked glycans

1 reference

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7 January 2021

The galactosyltransferase family

1 reference

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Importance of glycosidases in mammalian glycoprotein biosynthesis

1 reference

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7 January 2021

Structure and function of Class I alpha 1,2-mannosidases involved in glycoprotein synthesis and endoplasmic reticulum quality control

1 reference

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7 January 2021

Transporters of nucleotide sugars, ATP, and nucleotide sulfate in the endoplasmic reticulum and Golgi apparatus

1 reference

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7 January 2021

Enhanced sialylation of recombinant erythropoietin in genetically engineered Chinese-hamster ovary cells

1 reference

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7 January 2021

Recombinant erythropoietin in urine

1 reference

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7 January 2021

Detection of isoelectric profiles of erythropoietin in urine: differentiation of natural and administered recombinant hormones

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7 January 2021

Detection of recombinant human erythropoietin in urine for doping analysis: Interpretation of isoelectric profiles by discriminant analysis

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7 January 2021

The Golgi CMP-sialic acid transporter: A new CHO mutant provides functional insights

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Mammalian glycosylation in immunity

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Regulation of glycan structures in animal tissues: transcript profiling of glycan-related genes

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7 January 2021

Point mutations identified in Lec8 Chinese hamster ovary glycosylation mutants that inactivate both the UDP-galactose and CMP-sialic acid transporters

1 reference

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7 January 2021

Molecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal VI) that sialylates type II lactosamine structures on glycoproteins and glycolipids

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7 January 2021

Biochemical assessment of erythropoietin products from Asia versus US Epoetin alfa manufactured by Amgen

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7 January 2021

Protein glucosylation and its role in protein folding

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7 January 2021

The heterodimeric structure of glucosidase II is required for its activity, solubility, and localization in vivo

1 reference

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7 January 2021

Applicability of different fluorescent dyes for isoform quantification on linear IPG gels

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Glycoengineering: the effect of glycosylation on the properties of therapeutic proteins

1 reference

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Biological consequences of overexpressing or eliminating N-acetylglucosaminyltransferase-TIII in the mouse

1 reference

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Endoplasmic reticulum glucosidase II is composed of a catalytic subunit, conserved from yeast to mammals, and a tightly bound noncatalytic HDEL-containing subunit

1 reference

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7 January 2021

Mice with a homozygous deletion of the Mgat2 gene encoding UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,2-N-acetylglucosaminyltransferase II: a model for congenital disorder of glycosylation type IIa

1 reference

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Engineering Chinese hamster ovary cells to maximize sialic acid content of recombinant glycoproteins

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Enhancing recombinant glycoprotein sialylation through CMP-sialic acid transporter over expression in Chinese hamster ovary cells

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A novel second isoenzyme of the human UDP-N-acetylglucosamine:alpha1,3-D-mannoside beta1,4-N-acetylglucosaminyltransferase family: cDNA cloning, expression, and chromosomal assignment

1 reference

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7 January 2021

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10.1016/J.YMBEN.2010.08.004

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Europe PubMed Central

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13 February 2020

PubMed publication ID

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20826224%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

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