(Q39658490)

13 September 2017

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title

Ofloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. (English)

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13 September 2017

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J P Monk

1

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13 September 2017

D M Campoli-Richards

series ordinal

2

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13 September 2017

publication date

1 April 1987

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13 September 2017

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13 September 2017

volume

33

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13 September 2017

issue

4

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13 September 2017

page(s)

346-391

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In-vitro activity of enoxacin (CL-919), a new quinoline derivative, compared with that of other antimicrobial agents

13 September 2017

cites work

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12 December 2020

Enoxacin raises plasma theophylline concentrations

1 reference

12 December 2020

Antichlamydial activity of quinolone carboxylic acids

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12 December 2020

In vitro evaluation of A-56619 and A-56620, two new quinolones

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12 December 2020

Ofloxacin: serum and skin blister fluid pharmacokinetics in the fasting and non-fasting state.

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12 December 2020

Clinical efficacy of ofloxacin in lower respiratory tract infections. A multicentre study

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12 December 2020

Antituberculosis activity of ofloxacin (DL 8280) on experimental tuberculosis in mice

1 reference

12 December 2020

Chemotherapeutic efficacy of ofloxacin on renal and subcutaneous infection models with Staphylococcus aureus in mice

1 reference

12 December 2020

The comparative activity of twelve 4-quinolone antimicrobials against Haemophilus influenzae and Streptococcus pneumoniae

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12 December 2020

Effect of 4-quinolones and novobiocin on calf thymus DNA polymerase alpha primase complex, topoisomerases I and II, and growth of mammalian lymphoblasts

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12 December 2020

Influence of pH and human urine on the antibacterial activity of ciprofloxacin, norfloxacin and ofloxacin

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12 December 2020

Antimicrobial chemotherapy of chlamydial infection: where next?

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12 December 2020

[Effect of pH value and magnesium on the antibacterial activity of quinolone preparations]

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12 December 2020

[Effect ofloxacin on Haemophilus influenza, Streptococcus pneumoniae and Neisseria meningitidis. Comparison with similar molecules]

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12 December 2020

In vitro activities of the spectinomycin analog U-63366 and four quinolone derivatives against Neisseria gonorrhoeae

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12 December 2020

Influence of ofloxacin, norfloxacin, nalidixic acid, pyromidic acid and pipemidic acid on human gamma-interferon production and blastogenesis

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12 December 2020

[Tissue concentration and effectiveness of ofloxacin in surgical patients].

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12 December 2020

Inhibition of Micrococcus luteus DNA gyrase by norfloxacin and 10 other quinolone carboxylic acids

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12 December 2020

Comparative in vitro activities of ciprofloxacin, enoxacin, norfloxacin, ofloxacin and pefloxacin against Bacteroides fragilis and Clostridium difficile

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12 December 2020

[In vitro activity of seven gyrase inhibitors of a group of heterocyclic carbonic acids against nonfermenting gram negative rods (nonfermenters)].

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12 December 2020

The comparative in vitro activity of twelve 4-quinolone antimicrobials against enteric pathogens

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12 December 2020

Therapeutic effect of a new antibacterial substance ofloxacin (DL8280) on pulmonary tuberculosis.

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12 December 2020

Dominant lethal study in male mice treated with ofloxacin, a new antimicrobial drug

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12 December 2020

The possible role of quinolones in yersiniosis

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12 December 2020

Antibacterial activity of coumermycin alone and in combination with other antibiotics

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12 December 2020

In vitro susceptibility of Campylobacter jejuni to 27 antimicrobial agents and various combinations of beta-lactams with clavulanic acid or sulbactam

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12 December 2020

In-vitro activity of newer quinolones against aerobic bacteria.

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12 December 2020

In vitro comparison of A-56619, A-56620, amifloxacin, ciprofloxacin, enoxacin, norfloxacin, and ofloxacin against methicillin-resistant Staphylococcus aureus

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12 December 2020

Differences in susceptibility to quinolones of outer membrane mutants of Salmonella typhimurium and Escherichia coli

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12 December 2020

Quinolones affect thymidine incorporation into the DNA of human lymphocytes

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12 December 2020

Quinolones and raised plasma concentrations of theophylline

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12 December 2020

Summarized results of clinical phase II and III studies with ofloxacin (HOE 280) in Europe

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12 December 2020

Comparison of the antibacterial in vitro and in vivo activity of ofloxacin (HOE 280 DL 8280) and nalidixic acid analogues

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12 December 2020

The fluoroquinolones: structures, mechanisms of action and resistance, and spectra of activity in vitro

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12 December 2020

The comparative in-vitro activity of twelve 4-quinolone antimicrobials against Haemophilus ducreyi

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12 December 2020

Multiple-dose pharmacokinetics of ofloxacin, a new broad-spectrum antimicrobial agent

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12 December 2020

Elimination of plasmids by new 4-quinolones

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12 December 2020

An investigation of the hydrophobicity of the quinolones

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12 December 2020

Antibacterial activity of amifloxacin (WIN 49, 375), a new quinolone agent.

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12 December 2020

The fluoroquinolones: pharmacology, clinical uses, and toxicities in humans

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12 December 2020

Pharmacokinetics of ofloxacin and theophylline alone and in combination

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12 December 2020

Comparative evaluation of recently developed quinolone compounds--with a note on the frequency of resistant mutants.

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12 December 2020

Comparative in vitro activity of seven quinolones against 100 clinical isolates of Clostridium difficile

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12 December 2020

Quinolones and colonization resistance in human volunteers.

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12 December 2020

Antichlamydial activity of ofloxacin

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12 December 2020

[In vitro activity, serum, urine and prostatic adenoma concentrations of ofloxacin in urologic patients with complicated urinary tract infections]

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12 December 2020

The influence of quinolone derivatives on theophylline clearance

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12 December 2020

[A cross-over study on the effectiveness of ofloxacin and ciprofloxacin administered orally]

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12 December 2020

Reproductive toxicity of ofloxacin

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12 December 2020

Ofloxacin: antibacterial activity, induction of resistance and killing curves

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12 December 2020

The effect of food on the pharmacokinetics of ofloxacin.

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12 December 2020

Purification and properties of DNA gyrase from a fluoroquinolone-resistant strain of Escherichia coli

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12 December 2020

Nalidixic Acid: an Antibacterial Paradox

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12 December 2020

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12 December 2020

Antimicrobial susceptibility of Serratia marcescens isolated from clinical materials

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12 December 2020

Antibacterial activity of ofloxacin and other 4-quinolone derivatives: in-vitro and in-vivo comparison.

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12 December 2020

In vitro activity of ciprofloxacin compared with those of other new fluorinated piperazinyl-substituted quinoline derivatives

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12 December 2020

Treatment of typhoid fever using ofloxacin. Clinical experience and determination of antibiotic diffusion into the mesenteric lymph nodes

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12 December 2020

The effect of altered porin expression in Escherichia coli upon susceptibility to 4-quinolones

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12 December 2020

[Comparative clinical study of DL-8280 and cefaclor for suppurative skin and soft tissue infections by a double-blind method]

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12 December 2020

Acute nongonococcal epididymitis. Aetiological and therapeutic aspects

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12 December 2020

Susceptibility of Clostridium difficile strains to new antibiotics: quinolones, efrotomycin, teicoplanin and imipenem

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12 December 2020

[Diffusion of an orally administered single dose of ofloxacin into human bronchial mucus]

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12 December 2020

Dose linearity and other pharmacokinetics of ofloxacin: a new, broad-spectrum antimicrobial agent

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12 December 2020

In vitro antituberculosis activity of a new antibacterial substance ofloxacin (DL8280).

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12 December 2020

[The antibacterial activity in vitro of ofloxacin in comparison with other orally administered antimicrobial substances on ampicillin-resistant clinical isolates]

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12 December 2020

Comparative in vitro activities of aztreonam, ciprofloxacin, norfloxacin, ofloxacin, HR 810 (a new cephalosporin), RU28965 (a new macrolide), and other agents against enteropathogens

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12 December 2020

[Comparative clinical study of ofloxacin and cefaclor in bacterial bronchitis]

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12 December 2020

Fluorinated quinolones. A review of their mode of action, antimicrobial activity, pharmacokinetics and clinical efficacy

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12 December 2020

Susceptibility of Legionella pneumophila to ofloxacin in vitro and in experimental Legionella pneumonia in guinea pigs

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12 December 2020

Comparative in vitro activities of ciprofloxacin and other 4-quinolones against Mycobacterium tuberculosis and Mycobacterium intracellulare

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12 December 2020

Antimycoplasmal activity of ofloxacin (DL-8280).

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12 December 2020

Chemotherapeutic effects of ofloxacin (HOE 280) and other quinolone-carboxylic derivates in the treatment of experimental lung infections due to Klebsiella pneumoniae DT-S in mice

1 reference

12 December 2020

Nalidixic acid-resistant mutations of the gyrB gene of Escherichia coli

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12 December 2020

The quinolones in chronic bronchitis

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12 December 2020

[Comparative studies of DL-8280 and pipemidic acid in complicated urinary tract infections by double-blind method]

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12 December 2020

Genetic and biochemical characterization of norfloxacin resistance in Escherichia coli

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12 December 2020

Comparative evaluation of ciprofloxacin, enoxacin, and ofloxacin in experimental Pseudomonas aeruginosa pneumonia

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12 December 2020

Effects of ethylenediaminetetraacetic acid and gentamicin on the antibacterial activity of pyridone carboxylic acid derivatives against gram-negative bacilli

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12 December 2020

[Animal experiment studies on the modification of the immune system by ofloxacin]

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12 December 2020

Comparative in vitro studies with 4-quinolone antimicrobials

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12 December 2020

Synthesis and antibacterial activities of optically active ofloxacin

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12 December 2020

In-vitro activity of ofloxacin, a quinolone carboxylic acid compared to other quinolones and other antimicrobial agents

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12 December 2020

Activities of new quinoline derivatives against genital pathogens

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12 December 2020

In-vitro activity of enoxacin, ofloxacin, norfloxacin and nalidixic acid

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12 December 2020

Ofloxacin in the conservative therapy of acute and chronic otitis media--a preliminary clinical report of experiences

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12 December 2020

Comparative in vitro activity of three new quinolone antibiotics against recent clinical isolates.

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12 December 2020

The comparative activity of twelve 4-quinolone antimicrobials against gram-positive and gram-negative anaerobes

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12 December 2020

In vitro activities of ciprofloxacin, ofloxacin, norfloxacin and rosoxacin compared with cinoxacin and trimethoprim

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12 December 2020

The in-vitro activities of enoxacin and ofloxacin compared with that of ciprofloxacin

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12 December 2020

The pharmacokinetics and tissue penetration of ofloxacin

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12 December 2020

10.2165/00003495-198733040-00003

Identifiers

DOI

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Dimensions Publication ID

13 September 2017

1040343572

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