(Q39675362)

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Hydrophobic bile acid-induced micronuclei formation, mitotic perturbations, and decreases in spindle checkpoint proteins: relevance to genomic instability in colon carcinogenesis

scientific article published on January 2010

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1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Hydrophobic bile acid-induced micronuclei formation, mitotic perturbations, and decreases in spindle checkpoint proteins: relevance to genomic instability in colon carcinogenesis (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

1 reference

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1 reference

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author name string

Claire M Payne

1

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Cheray Crowley-Skillicorn

2

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Carol Bernstein

3

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Hana Holubec

4

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Mary Pat Moyer

5

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Harris Bernstein

6

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Europe PubMed Central

PubMed publication ID

13 September 2017

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1 January 2010

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Nutrition and Cancer

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

62

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

825-840

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Environmental factors and cancer incidence and mortality in different countries, with special reference to dietary practices

1 reference

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21 January 2018

Diet and carcinogenesis

1 reference

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21 January 2018

Hypotheses for the etiology of colorectal cancer--an overview

1 reference

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21 January 2018

Metabolic epidemiology of colon cancer. Fecal bile acids and neutral sterols in colon cancer patients and patients with adenomatous polyps

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

Activation of the promoters of genes associated with DNA damage, oxidative stress, ER stress and protein malfolding by the bile salt, deoxycholate

1 reference

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21 January 2018

Deoxycholate induces mitochondrial oxidative stress and activates NF-kappaB through multiple mechanisms in HCT-116 colon epithelial cells

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

Sodium deoxycholate causes nitric oxide mediated DNA damage in oesophageal cells

1 reference

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21 January 2018

Role of mitochondrial complexes I and II, reactive oxygen species and arachidonic acid metabolism in deoxycholate-induced apoptosis

1 reference

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21 January 2018

Deoxycholic acid causes DNA damage in colonic cells with subsequent induction of caspases, COX-2 promoter activity and the transcription factors NF-kB and AP-1.

1 reference

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21 January 2018

The bile acid deoxycholic acid (DCA) at neutral pH activates NF-kappaB and induces IL-8 expression in oesophageal cells in vitro

1 reference

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21 January 2018

Unique dietary-related mouse model of colitis.

1 reference

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21 January 2018

Bile acids in combination with low pH induce oxidative stress and oxidative DNA damage: relevance to the pathogenesis of Barrett's oesophagus

1 reference

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21 January 2018

Genotoxic effect of bile acids on human normal and tumour colon cells and protection by dietary antioxidants and butyrate.

1 reference

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21 January 2018

The bile acid deoxycholic acid has a non-linear dose response for DNA damage and possibly NF-kappaB activation in oesophageal cells, with a mechanism of action involving ROS.

1 reference

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21 January 2018

Exposure of mouse colon to dietary bile acid supplement induces sessile adenomas

1 reference

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21 January 2018

Bile acids as carcinogens in human gastrointestinal cancers

1 reference

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21 January 2018

Glycochenodeoxycholate plays a carcinogenic role in immortalized mouse cholangiocytes via oxidative DNA damage

1 reference

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21 January 2018

Assessment of apoptosis by immunohistochemical markers compared to cellular morphology in ex vivo-stressed colonic mucosa

1 reference

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21 January 2018

Inhibition of proliferation and induction of monocytic differentiation on HL60 human promyelocytic leukemia cells treated with bile acids in vitro

1 reference

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21 January 2018

Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: the switch between apoptosis and necrosis.

1 reference

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21 January 2018

Modulation of the cell cycle and induction of apoptosis in human cancer cells by synthetic bile acids

1 reference

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21 January 2018

DNA damage responses: mechanisms and roles in human disease: 2007 G.H.A. Clowes Memorial Award Lecture

1 reference

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21 January 2018

DNA-damage checkpoints: location, location, location.

1 reference

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21 January 2018

Defining 'chromosomal instability'.

1 reference

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21 January 2018

Chromosome segregation and cancer: cutting through the mystery

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

On the road to cancer: aneuploidy and the mitotic checkpoint

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

Chromosomal instability in flat adenomas and carcinomas of the colon.

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

Epithelial and stromal genetic instability contributes to genesis of colorectal adenomas

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

Genetic instability and divergence of clonal populations in colon cancer cells in vitro.

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

Apoptosis overview emphasizing the role of oxidative stress, DNA damage and signal-transduction pathways

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

The in vitro micronucleus technique

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

Housekeeping genes commanded to commit suicide in CpG-cleavage commitment upstream of Bcl-2 inhibition in caspase-dependent and -independent pathways

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

Effect of high fat consumption on cell proliferation activity of colorectal mucosa and on soluble faecal bile acids

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

Nocodazole, a microtubule de-polymerising agent, induces apoptosis of chronic lymphocytic leukaemia cells associated with changes in Bcl-2 phosphorylation and expression

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

Caspase-6 mediated cleavage of guanylate cyclase alpha 1 during deoxycholate-induced apoptosis: protective role of the nitric oxide signaling module

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

Mitochondrial perturbation attenuates bile acid-induced cytotoxicity

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

The significance of unstable chromosomes in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

Chromosomal gains and losses in primary colorectal carcinomas detected by CGH and their associations with tumour DNA ploidy, genotypes and phenotypes

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

Genetic instability in colorectal cancers

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans.

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

Cohesin cleavage by separase required for anaphase and cytokinesis in human cells

1 reference

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21 January 2018

Resolution of anaphase bridges in cancer cells

1 reference

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21 January 2018

Structural and numerical chromosome changes in colon cancer develop through telomere-mediated anaphase bridges, not through mitotic multipolarity

1 reference

https://api.crossref.org/works/10.1080%2F01635581003695756

21 January 2018

Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers

1 reference

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21 January 2018

Classification of chromosome segregation errors in cancer

1 reference

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21 January 2018

The Behavior in Successive Nuclear Divisions of a Chromosome Broken at Meiosis

1 reference

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21 January 2018

The Fusion of Broken Ends of Chromosomes Following Nuclear Fusion

1 reference

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21 January 2018

When, where and how the bridge breaks: anaphase bridge breakage plays a crucial role in gene amplification and HSR generation

1 reference

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21 January 2018

The spindle checkpoint, aneuploidy, and cancer

1 reference

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21 January 2018

Direct role of PDGF-BB in lymphangiogenesis and lymphatic metastasis

1 reference

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21 January 2018

The spindle-assembly checkpoint in space and time

1 reference

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21 January 2018

Dual regulation of Mad2 localization on kinetochores by Bub1 and Dam1/DASH that ensure proper spindle interaction

1 reference

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21 January 2018

The spindle assembly checkpoint is satisfied in the absence of interkinetochore tension during mitosis with unreplicated genomes.

1 reference

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21 January 2018

A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy

1 reference

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21 January 2018

Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

1 reference

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21 January 2018

The Mad2 partial unfolding model: regulating mitosis through Mad2 conformational switching

1 reference

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21 January 2018

Localization of Mad2 to kinetochores depends on microtubule attachment, not tension

1 reference

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21 January 2018

Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit

1 reference

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21 January 2018

Basic mechanism of eukaryotic chromosome segregation

1 reference

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21 January 2018

Depression of MAD2 inhibits apoptosis of gastric cancer cells by upregulating Bcl-2 and interfering mitochondrion pathway

1 reference

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21 January 2018

Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability

1 reference

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21 January 2018

Opposing securin and p53 protein expression in the oxaliplatin-induced cytotoxicity of human colorectal cancer cells

1 reference

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21 January 2018

Expression of securin promotes colorectal cancer cell death via a p53-independent pathway after radiation

1 reference

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21 January 2018

Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy.

1 reference

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21 January 2018

Role of apoptosis in biology and pathology: resistance to apoptosis in colon carcinogenesis

1 reference

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21 January 2018

p53 activation in response to mitotic spindle damage requires signaling via BubR1-mediated phosphorylation.

1 reference

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21 January 2018

Reduced level of the spindle checkpoint protein BUB1B is associated with aneuploidy in colorectal cancers

1 reference

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21 January 2018

Micronuclei induction, cell cycle delay and apoptosis as markers of cellular stress caused by ursodeoxycholic acid in human lymphocytes.

1 reference

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21 January 2018

Prevention of N-methylnitrosourea-induced colon tumorigenesis by ursodeoxycholic acid in F344 rats.

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21 January 2018

Ursodeoxycholic acid as a chemopreventive agent in patients with ulcerative colitis and primary sclerosing cholangitis

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21 January 2018

Ursodeoxycholic acid therapy and the risk of colorectal adenoma in patients with primary biliary cirrhosis: an observational study

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21 January 2018

Gender modifies the effect of ursodeoxycholic acid in a randomized controlled trial in colorectal adenoma patients

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21 January 2018

Phase III trial of ursodeoxycholic acid to prevent colorectal adenoma recurrence

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21 January 2018

Differential effects of deoxycholic acid and taurodeoxycholic acid on NF-kappa B signal transduction and IL-8 gene expression in colonic epithelial cells

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21 January 2018

Hsp70 overexpression sequesters AIF and reduces neonatal hypoxic/ischemic brain injury.

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21 January 2018

Therapeutic potential of AIF-mediated caspase-independent programmed cell death.

1 reference

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21 January 2018

Functional modulation of the glucocorticoid receptor and suppression of NF-kappaB-dependent transcription by ursodeoxycholic acid

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21 January 2018

Differential regulation of cyclin D1 and cell death by bile acids in primary rat hepatocytes

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21 January 2018

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10.1080/01635581003695756

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

release_6m66gkcvoncjpdcnugbndad5ui

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https://api.fatcat.wiki/v0/release/6m66gkcvoncjpdcnugbndad5ui

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

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