(Q39683076)

English

Novel immediate-early protein IE19 of human cytomegalovirus activates the origin recognition complex I promoter in a cooperative manner with IE72.

scientific article published on April 2002

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scholarly article

1 reference

Europe PubMed Central

13 September 2017

Novel immediate-early protein IE19 of human cytomegalovirus activates the origin recognition complex I promoter in a cooperative manner with IE72. (English)

1 reference

Europe PubMed Central

13 September 2017

Cytomegalovirus

0 references

author name string

Masaki Shirakata

1

1 reference

Europe PubMed Central

13 September 2017

Masakazu Terauchi

2

1 reference

Europe PubMed Central

13 September 2017

Melike Ablikim

3

1 reference

Europe PubMed Central

13 September 2017

Ken-Ichi Imadome

4

1 reference

Europe PubMed Central

13 September 2017

Kanji Hirai

5

1 reference

Europe PubMed Central

13 September 2017

Takeshi Aso

6

1 reference

Europe PubMed Central

13 September 2017

Yuji Yamanashi

7

1 reference

Europe PubMed Central

13 September 2017

language of work or name

0 references

publication date

1 April 2002

1 reference

Europe PubMed Central

13 September 2017

Journal of Virology

1 reference

Europe PubMed Central

13 September 2017

76

1 reference

Europe PubMed Central

13 September 2017

7

1 reference

Europe PubMed Central

13 September 2017

3158-3167

1 reference

Europe PubMed Central

13 September 2017

The retinoblastoma protein as a transcriptional repressor

1 reference

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Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis

1 reference

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14 September 2017

Cooperation of E2F-p130 and Sp1-pRb complexes in repression of the Chinese hamster dhfr gene

1 reference

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14 September 2017

The human cytomegalovirus IE2 and UL112-113 proteins accumulate in viral DNA replication compartments that initiate from the periphery of promyelocytic leukemia protein-associated nuclear bodies (PODs or ND10)

1 reference

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14 September 2017

Cytomegalovirus IE2 protein stimulates interleukin 1beta gene transcription via tethering to Spi-1/PU.1.

1 reference

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14 September 2017

The organization of replication and transcription

1 reference

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14 September 2017

Function of TAF(II)-containing complex without TBP in transcription by RNA polymerase II

1 reference

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14 September 2017

Separate DNA elements containing ATF/CREB and IE86 binding sites differentially regulate the human cytomegalovirus UL112-113 promoter at early and late times in the infection

1 reference

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14 September 2017

Formation of cytomegalovirus DNA replication compartments defined by localization of viral proteins and DNA synthesis

1 reference

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14 September 2017

Transcription factor Sp1 mediates cell-specific trans-activation of the human cytomegalovirus DNA polymerase gene promoter by immediate-early protein IE86 in glioblastoma U373MG cells.

1 reference

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14 September 2017

TAF-like functions of human cytomegalovirus immediate-early proteins

1 reference

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14 September 2017

Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs

1 reference

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14 September 2017

Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor

1 reference

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14 September 2017

Evidence that the UL84 gene product of human cytomegalovirus is essential for promoting oriLyt-dependent DNA replication and formation of replication compartments in cotransfection assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

A deletion mutant in the human cytomegalovirus gene encoding IE1(491aa) is replication defective due to a failure in autoregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

The IE2 regulatory protein of human cytomegalovirus induces expression of the human transforming growth factor beta1 gene through an Egr-1 binding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

In vivo structure of the human cdc2 promoter: release of a p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

Multiple regulatory events influence human cytomegalovirus DNA polymerase (UL54) expression during viral infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

Identification and mapping of dimerization and DNA-binding domains in the C terminus of the IE2 regulatory protein of human cytomegalovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

Direct interaction of the human cytomegalovirus IE86 protein with the cis repression signal does not preclude TBP from binding to the TATA box.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

Human cytomegalovirus immediate-early gene 2 protein interacts with itself and with several novel cellular proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

Identification of sequence elements in the human cytomegalovirus DNA polymerase gene promoter required for activation by viral gene products.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

CCAAT box-dependent activation of the TATA-less human DNA polymerase alpha promoter by the human cytomegalovirus 72-kilodalton major immediate-early protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

Isolation and characterization of a low-abundance splice variant from the human cytomegalovirus major immediate-early gene region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

Functional interaction between the human cytomegalovirus 86-kilodalton IE2 protein and the cellular transcription factor CREB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

The multidomain structure of Orc1p reveals similarity to regulators of DNA replication and transcriptional silencing

1 reference

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14 September 2017

Conserved initiator proteins in eukaryotes

1 reference

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14 September 2017

Promoter-regulatory region of the major immediate early gene of human cytomegalovirus

1 reference

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14 September 2017

Structural analysis of the major immediate early gene of human cytomegalovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

Organization and expression of the immediate early genes of human cytomegalovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

Temporal Patterns of Human Cytomegalovirus Transcription: Mapping the Viral RNAs Synthesized at Immediate Early, Early, and Late Times After Infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

Temporal regulation of human cytomegalovirus transcription at immediate early and early times after infection

1 reference

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14 September 2017

Patterns of Transcription of Human Cytomegalovirus in Permissively Infected Cells

1 reference

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14 September 2017

Identification and characterization of the human cytomegalovirus immediate-early region 2 gene that stimulates gene expression from an inducible promoter

1 reference

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14 September 2017

Autoregulation of the human cytomegalovirus major immediate-early gene

1 reference

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Multiple spliced and unspliced transcripts from human cytomegalovirus immediate-early region 2 and evidence for a common initiation site within immediate-early region 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

Analysis of the major transcripts encoded by the long repeat of human cytomegalovirus strain AD169.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

Regulated expression of early and late RNAs and proteins from the human cytomegalovirus immediate-early gene region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

Regulated expression of the human cytomegalovirus pp65 gene: octamer sequence in the promoter is required for activation by viral gene products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

Promoter-specific trans activation and repression by human cytomegalovirus immediate-early proteins involves common and unique protein domains

1 reference

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14 September 2017

Transactivation of a human cytomegalovirus early promoter by gene products from the immediate-early gene IE2 and augmentation by IE1: mutational analysis of the viral proteins

1 reference

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ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

1 reference

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E2F: a link between the Rb tumor suppressor protein and viral oncoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

E2F mediates dihydrofolate reductase promoter activation and multiprotein complex formation in human cytomegalovirus infection

1 reference

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Nuclear organization of DNA replication in primary mammalian cells.

1 reference

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Identification of a viral kinase that phosphorylates specific E2Fs and pocket proteins

1 reference

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Binding of SP1 to the immediate-early protein-responsive element of the human cytomegalovirus DNA polymerase promoter

1 reference

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14 September 2017

Induction of the transcription factor Sp1 during human cytomegalovirus infection mediates upregulation of the p65 and p105/p50 NF-kappaB promoters

1 reference

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14 September 2017

CREB and CREB-binding proteins play an important role in the IE2 86-kilodalton protein-mediated transactivation of the human cytomegalovirus 2.2-kilobase RNA promoter.

1 reference

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14 September 2017

Four of eleven loci required for transient complementation of human cytomegalovirus DNA replication cooperate to activate expression of replication genes.

1 reference

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14 September 2017

Human cytomegalovirus IE86 protein interacts with promoter-bound TATA-binding protein via a specific region distinct from the autorepression domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

Eleven loci encoding trans-acting factors are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA replication.

1 reference

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14 September 2017

Transactivation by the human cytomegalovirus IE2 86-kilodalton protein requires a domain that binds to both the TATA box-binding protein and the retinoblastoma protein.

1 reference

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Transcriptional activation by the human cytomegalovirus immediate-early proteins: requirements for simple promoter structures and interactions with multiple components of the transcription complex.

1 reference

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14 September 2017

The human cytomegalovirus IE2 86-kilodalton protein interacts with an early gene promoter via site-specific DNA binding and protein-protein associations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136045

14 September 2017

Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

1 reference

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14 September 2017

Interaction of the 72-kilodalton human cytomegalovirus IE1 gene product with E2F1 coincides with E2F-dependent activation of dihydrofolate reductase transcription

1 reference

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Human cytomegalovirus US3 and UL36-38 immediate-early proteins regulate gene expression

1 reference

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14 September 2017

The human cytomegalovirus 80-kilodalton but not the 72-kilodalton immediate-early protein transactivates heterologous promoters in a TATA box-dependent mechanism and interacts directly with TFIID.

1 reference

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14 September 2017

Major product pp43 of human cytomegalovirus U(L)112-113 gene is a transcriptional coactivator with two functionally distinct domains

1 reference

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An isoform variant of the cytomegalovirus immediate-early auto repressor functions as a transcriptional activator

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15 June 2018

The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulatio

1 reference

https://pubmed.ncbi.nlm.nih.gov/11884540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of p53, retinoblastoma and host replication proteins at sites of viral replication in herpes-infected cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11884540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome

1 reference

https://pubmed.ncbi.nlm.nih.gov/11884540

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based on heuristic

inferred from PubMed ID database lookup

Yeast origin recognition complex functions in transcription silencing and DNA replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/11884540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.76.7.3158-3167.2002

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

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