(Q39684689)

14 September 2017

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title

Drug resistance and DNA repair (English)

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14 September 2017

M Fox

1

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14 September 2017

J J Roberts

series ordinal

2

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14 September 2017

publication date

1 January 1987

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Cancer and Metastasis Reviews

14 September 2017

published in

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14 September 2017

volume

6

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14 September 2017

issue

3

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14 September 2017

page(s)

261-281

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https://scigraph.springernature.com/pub.10.1007/bf00144267

14 September 2017

exact match

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cites work

Quenching of DNA:platinum(II) monoadducts as a possible mechanism of resistance to cis-diamminedichloroplatinum(II) in L1210 cells.

1 reference

12 December 2020

Cloning of the E. coli O6-methylguanine and methylphosphotriester methyltransferase gene using a functional DNA repair assay

1 reference

12 December 2020

DNA sequence has an effect on the extent and kinds of alkylation of DNA by a potent carcinogen

1 reference

12 December 2020

Emergence of nitrosourea resistant sublines of Lewis lung tumour following MeCCNU treatment in vivo

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12 December 2020

The use of recombinant DNA techniques to study radiation-induced damage, repair and genetic change in mammalian cells

1 reference

12 December 2020

Different genetic alterations underlie dual hypersensitivity of CHO mutant UV-1 to DNA methylating and cross-linking agents

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12 December 2020

The Escherichia coli O6-methylguanine-DNA methyltransferase does not repair promutagenic O6-methylguanine residues when present in Z-DNA

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12 December 2020

Preferential repair of nuclear matrix associated DNA in xeroderma pigmentosum complementation group C

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12 December 2020

Differential responses of nascent DNA synthesis and chain elongation in V79 and V79/79 cells exposed to u.v. light and chemical mutagens

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12 December 2020

Genetic effects of deoxyribonucleotide pool imbalances

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12 December 2020

Mechanisms for changing gene expression and their possible relationship to carcinogenesis

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12 December 2020

Measurements of DNA damage in Chinese hamster cells treated with equitoxic and equimutagenic doses of nitrosoureas

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12 December 2020

Large-scale isolation of UV-sensitive clones of CHO cells

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12 December 2020

The 1985 Walter Hubert lecture. Malignant cell differentiation as a potential therapeutic approach

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12 December 2020

The effect of cis-dichlorodiammineplatinum(II) on Escherichia coli B the role of fil, exr and hcr markers

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12 December 2020

Use of exonuclease III to determine the site of stable lesions in defined sequences of DNA: the cyclobutane pyrimidine dimer and cis and trans dichlorodiammine platinum II examples

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12 December 2020

DNA-mediated cotransfer of excision repair capacity and drug resistance into chinese hamster ovary mutant cell line UV-135

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12 December 2020

Mutagenicity, cytotoxicity, and DNA binding of platinum(II)-chloroammines in Chinese hamster ovary cells

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12 December 2020

Rationale for the use of alternating non-cross-resistant chemotherapy.

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12 December 2020

Human brain tumour cell strains with deficient host-cell reactivation of N-methyl-N′-nitro-N-nitrosoguanidine-damaged adenovirus 5

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12 December 2020

Molecular cloning and chromosomal localization of DNA sequences associated with a human DNA repair gene

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12 December 2020

Genetic diversity of UV-sensitive DNA repair mutants of Chinese hamster ovary cells

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12 December 2020

Defective repair of alkylated DNA by human tumour and SV40-transformed human cell strains

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12 December 2020

Reactions of the UVRABC excision nuclease with DNA damaged by diamminedichloroplatinum(II).

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12 December 2020

The use of recombinant DNA plasmids for the determination of DNA-repair and recombination in cultured mammalian cells.

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12 December 2020

Relative mutagenicity of antineoplastic drugs and other alkylating agents in V79 Chinese hamster cells, independence of cytotoxic and mutagenic responses

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12 December 2020

The effects of exogenous thymidine on endogenous deoxynucleotides and mutagenesis in mammalian cells

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12 December 2020

The genetic toxicology of nitrogen and sulphur mustard

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12 December 2020

DNA repair, DNA synthesis and cell cycle delay in human lymphoblastoid cells differentially sensitive to the cytotoxic effects of nitrogen mustard

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12 December 2020

Adaptive response in mammalian cells: crossreactivity of different pretreatments on cytotoxicity as contrasted to mutagenicity

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12 December 2020

Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells

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12 December 2020

Mechanism of UV-induced deoxynucleoside triphosphate pool imbalance in CHO-K1 cells

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12 December 2020

DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall.

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12 December 2020

Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue

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12 December 2020

Poly (ADP-Ribose) synthetase. Separation and identification of three proteolytic fragments as the substrate-binding domain, the DNA-binding domain, and the automodification domain

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12 December 2020

DNA methylation and cancer

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12 December 2020

X-ray-sensitive mutants of Chinese hamster ovary cell line isolation and cross-sensitivity to other DNA-damaging agents

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12 December 2020

Investigation of the cell cycle response of normal and Fanconi's anaemia fibroblasts to nitrogen mustard using flow cytometry

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12 December 2020

Effect of cis-platinum(II)diamminodichloride on wild type and deoxyribonucleic acid repair deficient mutants of Escherichia coli

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12 December 2020

The stability of methylated purines and of methylphosphotriesters in the DNA of V79 cells after treatment with N-methyl-N-nitrosourea

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12 December 2020

Purification and structure of the intact Ada regulatory protein of Escherichia coli K12, O6-methylguanine-DNA methyltransferase.

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12 December 2020

The role of suppression of DNA synthesis and inhibition of cell cycle progression in cellular sensitivity to alkylation damage

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12 December 2020

Mutagenic responses of thirteen anticancer drugs on mutation induction at multiple genetic loci and on sister chromatid exchanges in Chinese hamster ovary cells

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12 December 2020

Walker rat carcinoma cells are exceptionally sensitive to cis-diamminedichloroplatinum(II) (cisplatin) and other difunctional agents but not defective in the removal of platinum-DNA adducts.

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12 December 2020

In vivo effects of cis- and trans-diamminedichloroplatinum(II) on SV40 chromosomes: differential repair, DNA-protein cross-linking, and inhibition of replication

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12 December 2020

DNA-protein and DNA interstrand cross-linking by cis- and trans-platinum(II) diamminedichloride in L1210 mouse leukemia cells and relation to cytotoxicity

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12 December 2020

Nucleotide excision repair of DNA in eukaryotes: comparisons between human cells and yeast

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12 December 2020

Complementation analysis of ataxia-telangiectasia.

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12 December 2020

Binding of the antitumor drug cis-diamminedichloroplatinum(II) (cisplatin) to DNA.

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12 December 2020

Thermal enhancement of DNA damage in mammalian cells treated with cis-diamminedichloroplatinum(II)

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12 December 2020

Evidence for the excision repair of O6-n-butyldeoxyguanosine in human cells

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12 December 2020

Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis

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12 December 2020

Increasing metastatic potential is associated with increasing genetic instability of clones isolated from murine neoplasms

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12 December 2020

The unique sensitivity of Walker rat tumour cells to difunctional agents is associated with a failure to recover from inhibition of DNA synthesis and increased chromosome damage.

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12 December 2020

A screening method for isolating DNA repair-deficient mutants of CHO cells

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12 December 2020

A comparative analysis of drug-induced DNA effects in a nitrogen mustard resistant cell line expressing sensitivity to nitrosoureas

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12 December 2020

Specificity in carcinogen-DNA interaction: a theoretical exploration of the factors involved in the effect of neighboring bases on N-methyl-N-nitrosourea alkylation of DNA.

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12 December 2020

Increased repair of O6-alkylguanine DNA adducts in glioma-derived human cells resistant to the cytotoxic and cytogenetic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea.

1 reference

12 December 2020

Synergistic lethal effect of cis-dichlorodiammineplatinum and 1-beta-D-arabinofuranosylcytosine

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12 December 2020

Repair of O6-propylguanine and O6-butylguanine in DNA by O6-alkylguanine-DNA alkyltransferases from rat liver and E. coli

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12 December 2020

Hypomethylation of DNA in Raji cells after treatment with N-methyl-N-nitrosourea

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12 December 2020

Replication bypass model of sister chromatid exchanges and implications for Bloom's Syndrome and Fanconi's anemia

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12 December 2020

Antitumour imidazotetrazines-X. Effect of 8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4-(3H)-one (CCRG 81045; M & B 39831; NSC 362856) on DNA methylation during induction of haemoglobin synthesis in human leukaemia cell line K562

1 reference

12 December 2020

Reduction of the toxicity and mutagenicity of alkylating agents in mammalian cells harboring the Escherichia coli alkyltransferase gene

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12 December 2020

Inactivation of purified human O6-alkylguanine-DNA alkyltransferase by alkylating agents or alkylated DNA

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12 December 2020

Facilitation of tumour progression by cancer therapy

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12 December 2020

Induction of resistance to alkylating agents in E. coli: the ada+ gene product serves both as a regulatory protein and as an enzyme for repair of mutagenic damage

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12 December 2020

Transfection of DNA from a chloroethylnitrosourea-resistant tumor cell line (MER+) to a sensitive tumor cell line (MER-) results in a tumor cell line resistant to MNNG and CNU that has increased O-6-methylguanine-DNA methyltransferase levels and red

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12 December 2020

Overreplication and recombination of DNA in higher eukaryotes: potential consequences and biological implications

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12 December 2020

Survival of UV-irradiated mammalian cells correlates with efficient DNA repair in an essential gene

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12 December 2020

The effect of monofunctional or difunctional platinum adducts and of various other associated DNA damage on the expression of transfected DNA in mammalian cell lines sensitive or resistant to difunctional agents.

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12 December 2020

Molecular cloning of a gene which regulates the adaptive response to alkylating agents in Escherichia coli

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12 December 2020

Repair of O6-(2-chloroethyl)guanine mediates the biological effects of chloroethylnitrosoureas

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12 December 2020

DNA cross-linking and monoadduct repair in nitrosourea-treated human tumour cells

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12 December 2020

Expression of the E. coli O6-methylguanine-methylphosphotriester methyltransferase gene in mammalian cells.

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12 December 2020

Altering gene expression with 5-azacytidine

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12 December 2020

Investigations into the mechanisn of action of antitumour platinum compounds: Time- and dose-dependent changes in the alkaline sucrose gradient sedimentation profiles of DNA from hamster cells treated with cis-platinum(II) diamminedichloride

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12 December 2020

Excision repair of cis-diamminedichloroplatinum(II)-induced damage to DNA of Chinese hamster cells

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12 December 2020

HeLa cell variants that differ in sensitivity to monofunctional alkylating agents, with independence of cytotoxic and mutagenic responses

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12 December 2020

Inhibition of DNA methylation by chemical carcinogens in vitro

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12 December 2020

DNA repair-associated ADP-ribosylation in vivo. Modification of histone H1 differs from that of the principal acceptor proteins

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12 December 2020

Expression of a Bacterial Gene in Mammalian Cells

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12 December 2020

The cytotoxic and mutagenic effects of alkylating agents on human lymphoid cells are caused by different DNA lesions.

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12 December 2020

Pretreatment of Chinese hamster v79 cells with MNU increases survival without affecting DNA repair or mutagenicity.

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12 December 2020

Azacytidine-induced reactivation of a DNA repair gene in Chinese hamster ovary cells

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12 December 2020

The molecular nature of mutations in cultured mammalian cells: a review

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12 December 2020

Isolation and characterization of Chinese hamster ovary cell lines sensitive to mitomycin C and bleomycin.

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12 December 2020

Inability of Chinese hamster ovary cells to excise O6-alkylguanine

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12 December 2020

Quantitative aspects of the formation and loss of DNA interstrand crosslinks in Chinese hamster cells following treatment with cis-diamminedichloroplatinum(II) (cisplatin) II. Comparison of results from alkaline elution, DNA renaturation and DNA sedi

1 reference

12 December 2020

Gene amplification: an example of accelerated evolution in tumorigenic cells

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12 December 2020

Mechanisms of carcinogenesis induced by alkylating agents

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12 December 2020

A comparison of cell survival, mutation and persistence of putative promutagenic lesions in Chinese hamster cells exposed to BNU or MNU.

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12 December 2020

Cellular defence mechanisms against alkylating agents

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12 December 2020

Molecular cloning of a human DNA repair gene

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12 December 2020

The role of O6-methylguanine-DNA methyltransferase in cell survival, mutagenesis and carcinogenesis

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12 December 2020

Interactions between mammalian cell DNA and inorganic platinum compounds. I. DNA interstrand cross-linking and cytotoxic properties of platinum(II) compounds

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12 December 2020

Distribution of u.v.-induced repair events in higher-order chromatin loops in human and hamster fibroblasts.

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12 December 2020

Induction and repair of DNA cross-links in chinese hamster ovary cells treated with various platinum coordination compounds in relation to platinum binding to DNA, cytotoxicity, mutagenicity, and antitumor activity

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12 December 2020

Increased sensitivity of UV-repair-deficient human cells to DNA bound platinum products which unlike thymine dimers are not recognized by an endonuclease extracted from Micrococcus luteus

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12 December 2020

The significance of DNA cross-linking to cis-diamminedichloroplatinum(II)-induced cytotoxicity in sensitive and resistant lines of murine leukemia L1210 cells.

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12 December 2020

Differential DNA repair in transcriptionally active and inactive proto-oncogenes: c-abl and c-mos

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12 December 2020

Differential toxicity of cis- and trans-diamminedichloroplatinum(II) toward mammalian cells: lack of influence of any difference in the rates of loss of their DNA-bound adducts

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12 December 2020

Identifiers

DOI

10.1007/BF00144267

1 reference

14 September 2017

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