(Q39690535)

14 September 2017

GPR40-induced insulin secretion by the novel agonist TAK-875: first clinical findings in patients with type 2 diabetes (English)

1 reference

14 September 2017

0 references

0 references

1 reference

T Araki

1

1 reference

14 September 2017

M Hirayama

series ordinal

2

1 reference

14 September 2017

S Hiroi

series ordinal

3

1 reference

14 September 2017

K Kaku

series ordinal

4

1 reference

14 September 2017

22 December 2011

1 reference

Diabetes, Obesity and Metabolism

14 September 2017

1 reference

14 September 2017

14

1 reference

14 September 2017

3

1 reference

14 September 2017

271-278

1 reference

The effect of intensive glycemic treatment on coronary artery calcification in type 1 diabetic participants of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study

14 September 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Achieving glycemic control in type 2 diabetes: a practical guide for clinicians on oral hypoglycemics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Oral therapies for diabetic hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Sulphonylurea-induced hypoglycaemia in type 2 diabetes mellitus: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Dipeptydil peptidase-4 inhibitors in type 2 diabetes: a meta-analysis of randomized clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

International Union of Pharmacology. LXXI. Free fatty acid receptors FFA1, -2, and -3: pharmacology and pathophysiological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Overexpression of GPR40 in pancreatic beta-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Stimulation of insulin secretion by infusion of free fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Acute effects of fatty acids on insulin secretion from rat and human islets of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Islet G protein-coupled receptors as potential targets for treatment of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet beta-cells: mediation by PLC and L-type Ca2+ channel and link to insulin release

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Role of GPR40 in fatty acid action on the beta cell line INS-1E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Role of metabolically generated reactive oxygen species for lipotoxicity in pancreatic β-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Fatty acid receptors as new therapeutic targets for diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Discovery of TAK-875: A Potent, Selective, and Orally Bioavailable GPR40 Agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Selective small-molecule agonists of G protein-coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

GPR40 is expressed in glucagon producing cells and affects glucagon secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Sulfonylureas uncouple glucose-dependence for GPR40-mediated enhancement of insulin secretion from INS-1E cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

Report of the Committee on the classification and diagnostic criteria of diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1463-1326.2011.01525.X

10.1111/J.1463-1326.2011.01525.X

21 January 2018

Identifiers

DOI

1 reference

14 September 2017

1 reference