(Q39692444)

English

Regulation of angiogenesis and invasion by human Pituitary tumor transforming gene (PTTG) through increased expression and secretion of matrix metalloproteinase-2 (MMP-2).

scientific article published on 10 November 2006

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Regulation of angiogenesis and invasion by human Pituitary tumor transforming gene (PTTG) through increased expression and secretion of matrix metalloproteinase-2 (MMP-2). (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

author name string

Mohammad T Malik

1

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Sham S Kakar

2

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

10 November 2006

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Molecular Cancer

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

5

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

61

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

https://scigraph.springernature.com/pub.10.1186/1476-4598-5-61

0 references

Pituitary tumor-transforming gene regulates multiple downstream angiogenic genes in thyroid cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Ectopic expression of PTTG1/securin promotes tumorigenesis in human embryonic kidney cells

1 reference

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14 September 2017

The role of gelatinases in colorectal cancer progression and metastasis

1 reference

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14 September 2017

Oncogenes and tumor angiogenesis: the question of vascular "supply" and vascular "demand".

1 reference

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14 September 2017

Matrix metalloproteinases: old dogs with new tricks

1 reference

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14 September 2017

Pituitary tumor transforming gene-null male mice exhibit impaired pancreatic beta cell proliferation and diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

A molecular signature of metastasis in primary solid tumors

1 reference

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14 September 2017

Vascular endothelial growth factor, its receptor KDR/Flk-1, and pituitary tumor transforming gene in pituitary tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Functional role of estrogen in pituitary tumor pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Diminished corneal angiogenesis in gelatinase A-deficient mice

1 reference

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14 September 2017

Mice lacking pituitary tumor transforming gene show testicular and splenic hypoplasia, thymic hyperplasia, thrombocytopenia, aberrant cell cycle progression, and premature centromere division

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Overexpression of matrix-metalloproteinase-9 in human breast cancer: a potential favourable indicator in node-negative patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

The role of matrix metalloproteinases in tumor angiogenesis and tumor metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Matrix metalloproteinases in tumor invasion and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Human pituitary tumor-transforming gene induces angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Pituitary tumor transforming gene (PTTG) regulates placental JEG-3 cell division and survival: evidence from live cell imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Activation of mitogen-activated protein kinase cascade regulates pituitary tumor-transforming gene transactivation function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

A novel binding factor facilitates nuclear translocation and transcriptional activation function of the pituitary tumor-transforming gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Cell cycle regulated expression and phosphorylation of hpttg proto-oncogene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Molecular cloning and characterization of the tumor transforming gene (TUTR1): a novel gene in human tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Matrix metalloproteinases and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Regulation of matrix metalloproteinase expression in tumor invasion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Metalloproteinases and tissue inhibitors of metalloproteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Pituitary tumor transforming gene (PTTG) expression in pituitary adenomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

hpttg, a human homologue of rat pttg, is overexpressed in hematopoietic neoplasms. Evidence for a transcriptional activation function of hPTTG

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Isolation and characterization of a pituitary tumor-transforming gene (PTTG)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Matrix metalloproteinase 2 releases active soluble ectodomain of fibroblast growth factor receptor 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Securin is overexpressed in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

14 September 2017

Effects of angiogenesis inhibitors on multistage carcinogenesis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

17 June 2018

Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

17 June 2018

Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

17 June 2018

Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

20 August 2018

Early multipotential pituitary focal hyperplasia in the alpha-subunit of glycoprotein hormone-driven pituitary tumor-transforming gene transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

20 August 2018

Production and Activation of Matrix Metalloproteinase-2 in Proliferative Diabetic Retinopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

20 August 2018

Expression of pituitary tumour transforming gene (PTTG) and fibroblast growth factor-2 (FGF-2) in human pituitary adenomas: relationships to clinical tumour behaviour.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

20 August 2018

Matrix metalloproteinase-2 (MMP-2) is associated with the risk for a relapse in postmenopausal patients with node-positive breast carcinoma treated with antiestrogen adjuvant therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

20 August 2018

The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1654177

20 August 2018

Dose-dependent effects of gonadotropin releasing hormone on matrix metalloproteinase (MMP)-2, and MMP-9 and tissue specific inhibitor of metalloproteinases-1 messenger ribonucleic acid levels in human decidual Stromal cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17096843

12 December 2020

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inferred from PubMed ID database lookup

Pituitary tumor transforming gene and fibroblast growth factor-2 expression: potential prognostic indicators in differentiated thyroid cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17096843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/17096843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Switch to the angiogenic phenotype during tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17096843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microscopic localization of active proteases by in situ zymography: detection of matrix metalloproteinase activity in vascular tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/17096843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17096843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced angiogenesis and tumor progression in gelatinase A-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17096843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase-2 immunoreactive protein: a marker of aggressiveness in breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17096843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of pituitary-tumour transforming gene in colorectal tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/17096843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibrinogen E-fragment inhibits the migration and tubule formation of human dermal microvascular endothelial cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17096843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning of pituitary tumor transforming gene 1 from ovarian tumors and its expression in tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17096843

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a polyclonal antibody to human pituitary tumor transforming gene 1 (PTTG1) protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17096843

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based on heuristic

inferred from PubMed ID database lookup

Expression of PTTG (pituitary tumor transforming gene) in esophageal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17096843

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1476-4598-5-61

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1476-4598-5-61

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

ResearchGate publication ID

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