(Q39702932)

15 January 2018

title

Proteasomal degradation unleashes the pro-death activity of androgen receptor (English)

1 reference

15 January 2018

author name string

Bradley Godfrey

1

1 reference

15 January 2018

Yuting Lin

2

1 reference

15 January 2018

Jeffery Larson

3

1 reference

15 January 2018

Bonnie Haferkamp

4

1 reference

15 January 2018

Jialing Xiang

5

1 reference

15 January 2018

publication date

18 May 2010

1 reference

15 January 2018

published in

Cell Research

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15 January 2018

volume

20

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15 January 2018

issue

10

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15 January 2018

page(s)

1138-1147

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15 January 2018

https://scigraph.springernature.com/pub.10.1038/cr.2010.65

exact match

0 references

cites work

Polyglutamine-expanded androgen receptor truncation fragments activate a Bax-dependent apoptotic cascade mediated by DP5/Hrk

1 reference

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Calpain-mediated androgen receptor breakdown in apoptotic prostate cancer cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Androgen receptor is a tumor suppressor and proliferator in prostate cancer

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Diverse roles of androgen receptor (AR) domains in AR-mediated signaling

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Androgen receptor-mediated apoptosis is regulated by photoactivatable androgen receptor ligands

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

The role of the polyglutamine tract in androgen receptor.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

GCP-mediated growth inhibition and apoptosis of prostate cancer cells via androgen receptor-dependent and -independent mechanisms

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Down-regulation of androgen receptor by 3,3'-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Androgen and its receptor promote Bax-mediated apoptosis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Structure and function of steroid receptor AF1 transactivation domains: induction of active conformations

17 June 2018

1 reference

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Role of androgen receptor in the progression of human prostate tumor cells to androgen independence and insensitivity

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

The role of the androgen receptor in the development of prostatic hyperplasia and prostate cancer

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Cloning and characterization of an androgen receptor N-terminal-interacting protein with ubiquitin-protein ligase activity.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Extended polyglutamine selectively interacts with caspase-8 and -10 in nuclear aggregates

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1).

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Increase of androgen-induced cell death and androgen receptor transactivation by BRCA1 in prostate cancer cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Inhibiting proteasomes in human HepG2 and LNCaP cells increases endogenous androgen receptor levels

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Pro-apoptotic treatment with an adenovirus encoding Bax enhances the effect of chemotherapy in ovarian cancer

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Trafficking of the androgen receptor in living cells with fused green fluorescent protein-androgen receptor

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Delineation of two distinct type 1 activation functions in the androgen receptor amino-terminal domain

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Activation of the human androgen receptor through a protein kinase A signaling pathway

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Androgen receptors: structures, mutations, antibodies and cellular dynamics

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Molecular cloning and structural analysis of complementary DNA of human and rat androgen receptors

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

The subnuclear three-dimensional image analysis of androgen receptor fused to green fluorescence protein

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Kennedy's disease: caspase cleavage of the androgen receptor is a crucial event in cytotoxicity

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702544

Androgen Receptors in Prostate Cancer

20 August 2018

1 reference

12 December 2020

Expression of extended polyglutamine sequentially activates initiator and effector caspases

1 reference

12 December 2020

Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor

1 reference

12 December 2020

Chaperones Hsp70 and Hsp40 suppress aggregate formation and apoptosis in cultured neuronal cells expressing truncated androgen receptor protein with expanded polyglutamine tract

1 reference

12 December 2020

Identification of three proline-directed phosphorylation sites in the human androgen receptor

1 reference

12 December 2020

Apoptosis: translating theory to therapy for prostate cancer

1 reference

12 December 2020

Identifiers

DOI

10.1038/CR.2010.65

1 reference

15 January 2018

PMCID

5702544

1 reference

15 January 2018

PubMed ID

20479785

1 reference

15 January 2018