(Q39702950)

English

Potent taccalonolides, AF and AJ, inform significant structure-activity relationships and tubulin as the binding site of these microtubule stabilizers

scientific article

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22040100%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Potent taccalonolides, AF and AJ, inform significant structure-activity relationships and tubulin as the binding site of these microtubule stabilizers (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22040100%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Tacca plantaginea

1 reference

taccalonolide A

1 reference

13,14-bis(acetyloxy)-3,22,25-trihydroxy-11,15,17,22,23-pentamethyl-4,21-dioxo-8,20-dioxaheptacyclo[13.10.0.0²,¹².0⁵,¹¹.0⁷,⁹.0¹⁶,²⁴.0¹⁹,²³]pentacos-18-en-10-yl acetate

1 reference

13,14,25-tris(acetyloxy)-3,22-dihydroxy-11,15,17,22,23-pentamethyl-4,21-dioxo-8,20-dioxaheptacyclo[13.10.0.0²,¹².0⁵,¹¹.0⁷,⁹.0¹⁶,²⁴.0¹⁹,²³]pentacos-18-en-10-yl acetate

1 reference

[(1R,5S,7S,9S,10R,11R,12R,13S,14R,15R,16S,17S,22S,23S,24R,25S)-10,13,14-triacetyloxy-3,22-dihydroxy-11,15,17,22,23-pentamethyl-4,21-dioxo-8,20-dioxaheptacyclo[13.10.0.02,12.05,11.07,9.016,24.019,23]pentacosa-2,18-dien-25-yl] acetate

1 reference

(10,13,14-Triacetyloxy-3,22-dihydroxy-11,15,17,22,23-pentamethyl-4,21-dioxo-8,20-dioxaheptacyclo[13.10.0.02,12.05,11.07,9.016,24.019,23]pentacosa-2,18-dien-25-yl) acetate

1 reference

Taccalonolide B

1 reference

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22040100%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

author name string

Jing Li

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22040100%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

April L Risinger

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22040100%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Zhongliang Chen

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22040100%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Lihong Hu

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22040100%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Susan L Mooberry

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22040100%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

language of work or name

0 references

publication date

8 November 2011

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22040100%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

full work available at URL

https://europepmc.org/articles/pmc3234588?pdf=render

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1021/ja209045k?email=unpaywall_01@example.com

Journal of the American Chemical Society

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22040100%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

133

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22040100%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

47

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22040100%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

19064-19067

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22040100%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

online access status

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1021/ja209045k?email=unpaywall_01@example.com

access restriction status

1 reference

based on heuristic

inferred from online access status

Identification and biological activities of new taccalonolide microtubule stabilizers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234588

14 September 2017

Cellular studies reveal mechanistic differences between taccalonolide A and paclitaxel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234588

14 September 2017

Microtubule-binding agents: a dynamic field of cancer therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234588

14 September 2017

Microtubules and resistance to tubulin-binding agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234588

14 September 2017

Microtubule active agents: beyond the taxane frontier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234588

14 September 2017

The taccalonolides: microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234588

14 September 2017

Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234588

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234588

20 August 2018

Microtubule interactions with chemically diverse stabilizing agents: thermodynamics of binding to the paclitaxel site predicts cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234588

20 August 2018

Taccalonolides E and A: Plant-derived steroids with microtubule-stabilizing activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234588

20 August 2018

Computational model of intracellular pharmacokinetics of paclitaxel.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234588

20 August 2018

Five taccalonolides from Tacca plantaginea

1 reference

https://pubmed.ncbi.nlm.nih.gov/22040100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taccalonolides W – Y, Three New Pentacyclic Steroids fromTacca plantaginea

1 reference

9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/HLCA.200890116

Identifiers

10.1021/JA209045K

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22040100%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22040100%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22040100%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

ResearchGate publication ID

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