(Q39707045)

English

Oestrogen-related receptor alpha inverse agonist XCT-790 arrests A549 lung cancer cell population growth by inducing mitochondrial reactive oxygen species production

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scholarly article

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Europe PubMed Central

PubMed publication ID

14 September 2017

Oestrogen-related receptor alpha inverse agonist XCT-790 arrests A549 lung cancer cell population growth by inducing mitochondrial reactive oxygen species production (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

reactive oxygen species

1 reference

based on heuristic

inferred from title

author name string

J Wang

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495589&resulttype=core&format=json

14 May 2020

Y Wang

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495589&resulttype=core&format=json

14 May 2020

C Wong

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495589&resulttype=core&format=json

14 May 2020

publication date

1 April 2010

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Cell Proliferation

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495589&resulttype=core&format=json

14 May 2020

43

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495589&resulttype=core&format=json

14 May 2020

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495589&resulttype=core&format=json

14 May 2020

103-113

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495589&resulttype=core&format=json

14 May 2020

Chemoprevention of breast cancer with selective oestrogen-receptor modulators

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen-related receptor alpha is critical for the growth of estrogen receptor-negative breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C delta activates IkappaB-kinase alpha to induce the p53 tumor suppressor in response to oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transcriptional coactivator PGC-1beta drives the formation of oxidative type IIX fibers in skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and functional study of estrogen receptor-related receptors in human prostatic cells and tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biology of mitochondrial uncoupling proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen-related receptor alpha directs peroxisome proliferator-activated receptor alpha signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen-related receptor alpha and estrogen-related receptor gamma associate with unfavorable and favorable biomarkers, respectively, in human breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen-related receptor alpha 1 actively antagonizes estrogen receptor-regulated transcription in MCF-7 mammary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neoadjuvant percutaneous 4-hydroxytamoxifen decreases breast tumoral cell proliferation: a prospective controlled randomized study comparing three doses of 4-hydroxytamoxifen gel to oral tamoxifen

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the human cyclin-dependent kinase inhibitor p18INK4c by the transcription factors E2F1 and Sp1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kaempferol is an estrogen-related receptor alpha and gamma inverse agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen-related receptor-alpha antagonist inhibits both estrogen receptor-positive and estrogen receptor-negative breast tumor growth in mouse xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen-related receptor alpha is essential for the expression of antioxidant protection genes and mitochondrial function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced mitochondrial biogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oestrogen receptor-related receptor alpha (ERRalpha) and oestrogen receptors (ERalpha and ERbeta) exhibit different gene expression in human colorectal tumour progression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biology of PPAR gamma in cancer: a critical review on existing lacunae

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha).

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the cyclin E gene by transcription factor E2F1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonists of peroxisome proliferator-activated receptor gamma inhibit cell growth in malignant melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen-related receptors stimulate pyruvate dehydrogenase kinase isoform 4 gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of peroxisome proliferator-activated receptor-gamma by troglitazone (TGZ) inhibits human lung cell growth.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a selective inverse agonist for the orphan nuclear receptor estrogen-related receptor alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Artesunate induces ROS-mediated apoptosis in doxorubicin-resistant T leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity of androgen receptor antagonist bicalutamide in prostate cancer cells is independent of NCoR and SMRT corepressors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppressing the activity of ERRalpha in 3T3-L1 adipocytes reduces mitochondrial biogenesis but enhances glycolysis and basal glucose uptake

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: a mechanism for transcriptional control of muscle glucose metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two organochlorine pesticides, toxaphene and chlordane, are antagonists for estrogen-related receptor alpha-1 orphan receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-talk between the androgen receptor and the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orphan nuclear receptors: from gene to function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of estrogen receptor-related receptors, a subfamily of orphan nuclear receptors, as new tumor biomarkers in ovarian cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulation of the estrogen-inducible pS2 breast cancer marker gene by the ERR family of orphan nuclear receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diethylstilbestrol regulates trophoblast stem cell differentiation as a ligand of orphan nuclear receptor ERR beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biomarkers for early effects of carcinogenic dual-acting PPAR agonists in rat urinary bladder urothelium in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen-related receptor alpha in human breast carcinoma as a potent prognostic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of ICI182,780 (Fulvestrant)-induced estrogen receptor-alpha degradation by the estrogen receptor-related receptor-alpha inverse agonist XCT790.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20447055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2184.2009.00659.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495589&resulttype=core&format=json

14 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495589&resulttype=core&format=json

14 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6495589&resulttype=core&format=json

14 May 2020

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