(Q39709676)

English

Norrin mediates neuroprotective effects on retinal ganglion cells via activation of the Wnt/beta-catenin signaling pathway and the induction of neuroprotective growth factors in Muller cells.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20427659%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Norrin mediates neuroprotective effects on retinal ganglion cells via activation of the Wnt/beta-catenin signaling pathway and the induction of neuroprotective growth factors in Muller cells (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20427659%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

retinal ganglion cell

1 reference

based on heuristic

inferred from title

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20427659%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

author name string

Roswitha Seitz

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20427659%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Simon Hackl

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20427659%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Thomas Seibuchner

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20427659%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Andreas Ohlmann

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20427659%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

language of work or name

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publication date

1 April 2010

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20427659%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20427659%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

30

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20427659%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

17

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20427659%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

5998-6010

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20427659%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Experimental induction of retinal ganglion cell death in adult mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of the Norrie disease gene mRNA by in situ hybridization

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic cleavage of beta-catenin by caspases: an in vitro analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a transformed rat retinal ganglion cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pigment epithelium derived factor as a neuroprotective agent against ischemic retinal injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wnt signalling: antagonistic Dickkopfs

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular defects and sensorineural deafness in a mouse model of Norrie disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Norrie disease is caused by mutations in an extracellular protein resembling C-terminal globular domain of mucins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the candidate gene for Norrie disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lens epithelium-derived growth factor: neuroprotection on rat retinal damage induced by N-methyl-D-aspartate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ectopic norrin induces growth of ocular capillaries and restores normal retinal angiogenesis in Norrie disease mutant mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adeno-associated viruses containing bFGF or BDNF are neuroprotective against excitotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-methyl-D-aspartate-induced neurotoxicity in the adult rat retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genomic response to retinal disease and injury: evidence for endothelin signaling from photoreceptors to glia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the Norrie disease pseudoglioma gene in sprouting angiogenesis during development of the retinal vasculature

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinase-dependent differentiation of a retinal ganglion cell precursor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Müller cells in the healthy and diseased retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational analysis of Norrin-Frizzled4 recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-methyl-D-aspartate receptors in the retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of tau antagonizes apoptosis by stabilizing beta-catenin, a mechanism involved in Alzheimer's neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotection in the juvenile rat model of light-induced retinopathy: evidence suggesting a role for FGF-2 and CNTF.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of Wnt signaling during photoreceptor degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: roles of glycogen synthase kinase-3 inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wnt signaling in neuroprotection and stem cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting excitotoxic/free radical signaling pathways for therapeutic intervention in glaucoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukemia inhibitory factor extends the lifespan of injured photoreceptors in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Norrin attenuates protease-mediated death of transformed retinal ganglion cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitotoxic death of retinal neurons in vivo occurs via a non-cell-autonomous mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Norrin promotes vascular regrowth after oxygen-induced retinal vessel loss and suppresses retinopathy in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The growth and behaviour of rat retinal Müller cells in vitro. 1. An improved method for isolation and culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Injury-induced upregulation of bFGF and CNTF mRNAS in the rat retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection of the rat retina from ischemic injury by brain-derived neurotrophic factor, ciliary neurotrophic factor, and basic fibroblast growth factor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular modelling of the Norrie disease protein predicts a cystine knot growth factor tertiary structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basic fibroblast growth factor: increased gene expression in inherited and light-induced photoreceptor degeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection of retinal ganglion cells from natural and axotomy-induced cell death in neonatal transgenic mice overexpressing bcl-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An animal model for Norrie disease (ND): gene targeting of the mouse ND gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinoschisislike alterations in the mouse eye caused by gene targeting of the Norrie disease gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraocular gene transfer of ciliary neurotrophic factor prevents death and increases responsiveness of rod photoreceptors in the retinal degeneration slow mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinal vasculature changes in Norrie disease mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional expression of disease-related genes in human and monkey retina.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell production and cell death in the generation of variation in neuron number

1 reference

https://pubmed.ncbi.nlm.nih.gov/20427659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0730-10.2010

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20427659%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20427659%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20427659%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

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