(Q39719888)

14 September 2017

The siRNA sequence and guide strand overhangs are determinants of in vivo duration of silencing (English)

1 reference

14 September 2017

Walter R Strapps

1

1 reference

14 September 2017

Victoria Pickering

2

1 reference

14 September 2017

Gladys T Muiru

3

1 reference

14 September 2017

Julie Rice

4

1 reference

14 September 2017

Stacey Orsborn

5

1 reference

14 September 2017

Barry A Polisky

6

1 reference

14 September 2017

Alan Sachs

7

1 reference

14 September 2017

Steven R Bartz

8

1 reference

14 September 2017

language of work or name

English

0 references

publication date

31 March 2010

1 reference

14 September 2017

Nucleic Acids Research

1 reference

14 September 2017

38

1 reference

14 September 2017

14

1 reference

14 September 2017

4788-4797

1 reference

Creative Commons Attribution-NonCommercial 2.5 Generic

14 September 2017

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Design and validation of siRNAs and shRNAs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

Effect of asymmetric terminal structures of short RNA duplexes on the RNA interference activity and strand selection

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

2'-O-methyl modification in mouse piRNAs and its methylase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

The mouse homolog of HEN1 is a potential methylase for Piwi-interacting RNAs

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

RNA interference and innate immunity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

Mouse Piwi-interacting RNAs are 2'-O-methylated at their 3' termini.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

HEN1 recognizes 21-24 nt small RNA duplexes and deposits a methyl group onto the 2' OH of the 3' terminal nucleotide

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

Expression profiling reveals off-target gene regulation by RNAi

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

Synthesis, deprotection, analysis and purification of RNA and ribozymes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

Chemical modification resolves the asymmetry of siRNA strand degradation in human blood serum

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

Methylation as a crucial step in plant microRNA biogenesis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

siDRM: an effective and generally applicable online siRNA design tool

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

Chemical modification of siRNAs to improve serum stability without loss of efficacy.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

RNAi-mediated gene silencing in non-human primates.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

Variations of the 3' protruding ends in synthetic short interfering RNA (siRNA) tested by microinjection in Drosophila embryos.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

RNA interference (RNA(i)) induction with various types of synthetic oligonucleotide duplexes in cultured human cells.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919711

Contributions of 3'-overhang to the dissociation of small interfering RNAs from the PAZ domain: molecular dynamics simulation study

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20360048

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKQ206

1 reference

14 September 2017

1 reference

14 September 2017

PubMed publication ID

20360048

1 reference