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A functional human Poly(A) site requires only a potent DSE and an A-rich upstream sequence.
scientific article published on 25 March 2010
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PMC publication ID
2876958
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20339349%20AND%20SRC:MED&resulttype=core&format=json
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29 January 2020
title
A functional human Poly(A) site requires only a potent DSE and an A-rich upstream sequence
(English)
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2876958
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29 January 2020
author
B Tian
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3
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2876958
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29 January 2020
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Nuno Miguel Nunes
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1
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2876958
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29 January 2020
Wencheng Li
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2
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2876958
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29 January 2020
André Furger
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4
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29 January 2020
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English
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25 March 2010
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2876958
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29 January 2020
published in
The EMBO Journal
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PMC publication ID
2876958
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29 January 2020
volume
29
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29 January 2020
issue
9
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29 January 2020
page(s)
1523-1536
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2876958
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29 January 2020
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Two G-rich regulatory elements located adjacent to and 440 nucleotides downstream of the core poly(A) site of the intronless melanocortin receptor 1 gene are critical for efficient 3' end processing
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U1A inhibits cleavage at the immunoglobulin M heavy-chain secretory poly(A) site by binding between the two downstream GU-rich regions
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Analysis of mRNA 3' end formation by modification interference: the only modifications which prevent processing lie in AAUAAA and the poly(A) site
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25 September 2017
Molecular architecture of the human pre-mRNA 3' processing complex
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15 June 2018
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15 June 2018
A novel function for the U2AF 65 splicing factor in promoting pre-mRNA 3'-end processing.
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15 June 2018
Multiple transcripts of the murine immunoglobulin epsilon membrane locus are generated by alternative splicing and differential usage of two polyadenylation sites
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15 June 2018
A 64 kd nuclear protein binds to RNA segments that include the AAUAAA polyadenylation motif
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15 June 2018
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20 August 2018
PolyA_DB 2: mRNA polyadenylation sites in vertebrate genes
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20 August 2018
Direct interactions between subunits of CPSF and the U2 snRNP contribute to the coupling of pre-mRNA 3' end processing and splicing.
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20 August 2018
The RNA tether from the poly(A) signal to the polymerase mediates coupling of transcription to cleavage and polyadenylation
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20 August 2018
Bioinformatic identification of candidate cis-regulatory elements involved in human mRNA polyadenylation
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20 August 2018
Upstream elements present in the 3'-untranslated region of collagen genes influence the processing efficiency of overlapping polyadenylation signals
1 reference
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Role of the Conserved AAUAAA Sequence: Four AAUAAA Point Mutants Prevent Messenger RNA 3′ End Formation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20339349
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/EMBOJ.2010.42
1 reference
stated in
Europe PubMed Central
PMC publication ID
2876958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20339349%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
PMC publication ID
2876958
1 reference
stated in
Europe PubMed Central
PMC publication ID
2876958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20339349%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
PubMed publication ID
20339349
1 reference
stated in
Europe PubMed Central
PMC publication ID
2876958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20339349%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
ResearchGate publication ID
42589469
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