(Q39722819)

English

Efficient 3'-end formation of human beta-globin mRNA in vivo requires sequences within the last intron but occurs independently of the splicing reaction

scientific article published on February 1, 1998

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scholarly article

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Europe PubMed Central

PMC publication ID

14 September 2017

Efficient 3'-end formation of human beta-globin mRNA in vivo requires sequences within the last intron but occurs independently of the splicing reaction (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

author name string

M. Antoniou

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9443963

3 December 2024

F. Geraghty

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9443963

3 December 2024

J. Hurst

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9443963

3 December 2024

F. Grosveld

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9443963

3 December 2024

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publication date

1 February 1998

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

full work available at URL

https://academic.oup.com/nar/article-pdf/26/3/721/6154614/26-3-721.pdf

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9443963

3 December 2024

https://europepmc.org/articles/PMC147328

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9443963

3 December 2024

https://europepmc.org/articles/PMC147328?pdf=render

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9443963

3 December 2024

http://academic.oup.com/nar/article-pdf/26/3/721/6154614/26-3-721.pdf

1 reference

10.1093/NAR/26.3.721

https://api.crossref.org/works/10.1093/NAR/26.3.721

3 December 2024

Nucleic Acids Research

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

26

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

3

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

721-729

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Splicing factors associate with hyperphosphorylated RNA polymerase II in the absence of pre-mRNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

A functional interaction between the carboxy-terminal domain of RNA polymerase II and pre-mRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Sequence of the polypyrimidine tract of the 3'-terminal 3' splicing signal can affect intron-dependent pre-mRNA processing in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

An intron enhancer recognized by splicing factors activates polyadenylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

An intron enhancer containing a 5' splice site sequence in the human calcitonin/calcitonin gene-related peptide gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

The human U1 snRNP-specific U1A protein inhibits polyadenylation of its own pre-mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Association with terminal exons in pre-mRNAs: a new role for the U1 snRNP?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Introns are essential for growth-regulated expression of the mouse thymidylate synthase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Lack of an effect of the efficiency of RNA 3'-end formation on the efficiency of removal of either the final or the penultimate intron in intact cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Sequences Within the Last Intron function in RNA 3'-End Formation in Cultured Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

HnRNP L binds a cis-acting RNA sequence element that enables intron-dependent gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Expression of abbreviated mouse dihydrofolate reductase genes in cultured hamster cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Two 3' sequences direct adult erythroid-specific expression of human beta-globin genes in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Introns increase transcriptional efficiency in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

The human beta-globin promoter; nuclear protein factors and erythroid specific induction of transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Comparison of intron-dependent and intron-independent gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

The human beta-globin gene contains multiple regulatory regions: identification of one promoter and two downstream enhancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Definition of the minimal requirements within the human beta-globin gene and the dominant control region for high level expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Heterologous introns can enhance expression of transgenes in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Biochemical Mechanisms of Constitutive and Regulated Pre-mRNA Splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Poly(A) signals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Intron requirement for expression of the human purine nucleoside phosphorylase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

The biochemistry of 3'-end cleavage and polyadenylation of messenger RNA precursors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Splicing as a requirement for biogenesis of functional 16S mRNA of simian virus 40

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

3'-end cleavage and polyadenylation of mRNA precursors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

The intron requirement for immunoglobulin gene expression is dependent upon the promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Intervening sequences increase efficiency of RNA 3' processing and accumulation of cytoplasmic RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Splicing and the formation of stable RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

14 September 2017

Mechanisms for selecting 5' splice sites in mammalian pre-mRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

25 September 2017

Upstream sequence elements enhance poly(A) site efficiency of the C2 complement gene and are phylogenetically conserved

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

25 September 2017

Ending the message is not so simple

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

25 September 2017

Pre-mRNA processing and the CTD of RNA polymerase II: the tail that wags the dog?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

15 June 2018

The human beta-globin gene 3' enhancer contains multiple binding sites for an erythroid-specific protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147328

15 June 2018

Direct interaction of the U1 snRNP-A protein with the upstream efficiency element of the SV40 late polyadenylation signal

1 reference

https://pubmed.ncbi.nlm.nih.gov/9443963

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between the U1 snRNP-A protein and the 160-kD subunit of cleavage-polyadenylation specificity factor increases polyadenylation efficiency in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9443963

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A minimal intron length but no specific internal sequence is required for splicing the large rabbit beta-globin intron

1 reference

https://pubmed.ncbi.nlm.nih.gov/9443963

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Splicing of messenger RNA precursors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9443963

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro polyadenylation is stimulated by the presence of an upstream intron

1 reference

https://pubmed.ncbi.nlm.nih.gov/9443963

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation of the AAUAAA polyadenylation signal depresses in vitro splicing of proximal but not distal introns

1 reference

https://pubmed.ncbi.nlm.nih.gov/9443963

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human U1A snRNP protein regulates polyadenylation via a direct interaction with poly(A) polymerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9443963

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NAR/26.3.721

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

ResearchGate publication ID

0 references

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