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English
Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus
scientific article published on April 1998
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instance of
scholarly article
1 reference
stated in
Q5412157
PMCID
147486
retrieved
14 September 2017
title
Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus
(English)
1 reference
stated in
Q5412157
PMCID
147486
retrieved
14 September 2017
main subject
lipid
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author name string
E G Marcusson
series ordinal
1
1 reference
stated in
Q5412157
PMCID
147486
retrieved
14 September 2017
B Bhat
series ordinal
2
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stated in
Q5412157
PMCID
147486
retrieved
14 September 2017
M Manoharan
series ordinal
3
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stated in
Q5412157
PMCID
147486
retrieved
14 September 2017
C F Bennett
series ordinal
4
1 reference
stated in
Q5412157
PMCID
147486
retrieved
14 September 2017
N M Dean
series ordinal
5
1 reference
stated in
Q5412157
PMCID
147486
retrieved
14 September 2017
language of work or name
English
0 references
publication date
1 April 1998
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stated in
Q5412157
PMCID
147486
retrieved
14 September 2017
published in
Nucleic Acids Research
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stated in
Q5412157
PMCID
147486
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14 September 2017
volume
26
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Q5412157
PMCID
147486
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14 September 2017
page(s)
2016-2023
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Q5412157
PMCID
147486
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14 September 2017
issue
8
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Q5412157
PMCID
147486
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14 September 2017
cites work
In vivo fate of phosphorothioate antisense oligodeoxynucleotides: predominant uptake by scavenger receptors on endothelial liver cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Mechanism of oligonucleotide release from cationic liposomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Cellular uptake mechanism for oligonucleotides: involvement of endocytosis in the uptake of phosphodiester oligonucleotides by a human colorectal adenocarcinoma cell line, HCT-15.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Progress in antisense oligonucleotide therapeutics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Treatment of glioblastoma U-87 by systemic administration of an antisense protein kinase C-alpha phosphorothioate oligodeoxynucleotide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
A serum-resistant cytofectin for cellular delivery of antisense oligodeoxynucleotides and plasmid DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Comparison of cellular binding and uptake of antisense phosphodiester, phosphorothioate, and mixed phosphorothioate and methylphosphonate oligonucleotides.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Modification of antisense phosphodiester oligodeoxynucleotides by a 5' cholesteryl moiety increases cellular association and improves efficacy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Electroporation enhances c-myc antisense oligodeoxynucleotide efficacy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Improved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Inhibition of protein kinase C-alpha expression in mice after systemic administration of phosphorothioate antisense oligodeoxynucleotides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Delivery of antisense oligodeoxyribonucleotides against the human epidermal growth factor receptor into cultured KB cells with liposomes conjugated to folate via polyethylene glycol
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Binding, uptake, and intracellular trafficking of phosphorothioate-modified oligodeoxynucleotides.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Characterization of oligonucleotide transport into living cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Mechanism of oligonucleotide uptake by cells: involvement of specific receptors?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Intracellular distribution of microinjected antisense oligonucleotides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Binding of oligonucleotides to cell membranes at acidic pH
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Inhibition of leukemia cell proliferation by receptor-mediated uptake of c-myb antisense oligodeoxynucleotides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Intracellular availability of unmodified, phosphorothioated and liposomally encapsulated oligodeoxynucleotides for antisense activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Analysis of oligonucleotide binding, internalization, and intracellular trafficking utilizing a novel radiolabeled crosslinker
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Biosynthesis in vitro of fucose-containing glycosphingolipids in human neuroblastoma IMR-32 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Functions and structures of ribonuclease H enzymes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
14 September 2017
Cellular distribution of phosphorothioate oligodeoxynucleotides in normal rodent tissues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
25 September 2017
The therapeutic potential of antisense oligonucleotides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
25 September 2017
Delivery of oligoribonucleotides to human hepatoma cells using cationic lipid particles conjugated to ferric protoporphyrin IX (heme).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
25 September 2017
Intracellular distribution and mechanism of delivery of oligonucleotides mediated by cationic lipids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
25 September 2017
Inhibition of growth of human tumor cell lines in nude mice by an antisense of oligonucleotide inhibitor of protein kinase C-alpha expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
25 September 2017
Evaluation of adjuvants that enhance the effectiveness of antisense oligodeoxynucleotides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
25 September 2017
Improved cellular delivery of antisense oligonucleotides using transferrin receptor antibody-oligonucleotide conjugates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
25 September 2017
Developing oligonucleotide therapeutics for human leukemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
15 June 2018
Enhanced biological activity of antisense oligonucleotides complexed with glycosylated poly-L-lysine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
15 June 2018
Inhibition of expression of the multidrug resistance-associated P-glycoprotein of by phosphorothioate and 5' cholesterol-conjugated phosphorothioate antisense oligonucleotides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
15 June 2018
The kinetic aspects of intracellular fluorescence labeling with TMA-DPH support the maturation model for endocytosis in L929 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
15 June 2018
Disposition of the 14C-labeled phosphorothioate oligonucleotide ISIS 2105 after intravenous administration to rats.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
15 June 2018
Biological activity of oligonucleotide-poly(L-lysine) conjugates: mechanism of cell uptake
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
15 June 2018
Rapid nuclear accumulation of injected oligodeoxyribonucleotides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
15 June 2018
Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
15 June 2018
Specific inhibition of hepatitis B viral gene expression in vitro by targeted antisense oligonucleotides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
15 June 2018
The uptake kinetics of chimeric oligodeoxynucleotide analogues in human leukaemia MOLT-4 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
15 June 2018
Delivery of plasmid DNA into mammalian cell lines using pH-sensitive liposomes: comparison with cationic liposomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
15 June 2018
Selective inhibition of mutant Ha-ras mRNA expression by antisense oligonucleotides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
15 June 2018
Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
15 June 2018
Gene inhibition using antisense oligodeoxynucleotides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
20 August 2018
Inhibition of protein kinase C-alpha expression in human A549 cells by antisense oligonucleotides inhibits induction of intercellular adhesion molecule 1 (ICAM-1) mRNA by phorbol esters.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
20 August 2018
Cellular and molecular barriers to gene transfer by a cationic lipid
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147486
retrieved
20 August 2018
Novel polyaminolipids enhance the cellular uptake of oligonucleotides
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9518498
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Enhanced delivery of synthetic oligonucleotides to human leukaemic cells by liposomes and immunoliposomes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9518498
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Specific suppression of human tumor necrosis factor-alpha synthesis by antisense oligodeoxynucleotides
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9518498
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Characterization of complexes of oligonucleotides with polyamidoamine starburst dendrimers and effects on intracellular delivery
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9518498
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Inhibition of cell adhesion to plastic substratum by phosphorothioate oligonucleotide
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9518498
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Overcoming multidrug resistance in human tumor cells using free and liposomally encapsulated antisense oligodeoxynucleotides
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9518498
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/NAR/26.8.2016
1 reference
stated in
Q5412157
PMCID
147486
retrieved
14 September 2017
PMCID
147486
1 reference
stated in
Q5412157
PMCID
147486
retrieved
14 September 2017
PubMed ID
9518498
1 reference
stated in
Q5412157
PMCID
147486
retrieved
14 September 2017
ResearchGate publication ID
279970032
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