(Q39735325)

14 September 2017

Structure-based quantitative structure--activity relationship modeling of estrogen receptor β-ligands (English)

1 reference

14 September 2017

Xialan Dong

1

1 reference

PubMed ID

21707397

14 September 2017

Solomon G Hilliard

series ordinal

2

1 reference

PubMed ID

21707397

14 September 2017

Weifan Zheng

series ordinal

3

1 reference

14 September 2017

1 June 2011

1 reference

Future Medicinal Chemistry

14 September 2017

1 reference

14 September 2017

3

1 reference

14 September 2017

8

1 reference

14 September 2017

933-945

1 reference

New selective estrogen receptor modulators (SERMs) in development

14 September 2017

1 reference

Rosiglitazone plus metformin to prevent type 2 diabetes mellitus

21 January 2018

1 reference

Fluticasone furoate nasal spray is effective and well tolerated for perennial allergic rhinitis in adolescents and adults

21 January 2018

1 reference

Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A

21 January 2018

1 reference

ER beta: identification and characterization of a novel human estrogen receptor

21 January 2018

1 reference

Human oestrogen receptors: differential expression of ER alpha and beta and the identification of ER beta variants

21 January 2018

1 reference

Reflections on the discovery and significance of estrogen receptor beta

21 January 2018

1 reference

Evaluation of an Estrogen Receptor-β Agonist in Animal Models of Human Disease

21 January 2018

1 reference

ERbeta ligands. Part 1: the discovery of ERbeta selective ligands which embrace the 4-hydroxy-biphenyl template

21 January 2018

1 reference

ERbeta ligands. Part 2: Synthesis and structure-activity relationships of a series of 4-hydroxy-biphenyl-carbaldehyde oxime derivatives

21 January 2018

1 reference

ERbeta ligands. Part 4: Synthesis and structure-activity relationships of a series of 2-phenylquinoline derivatives

21 January 2018

1 reference

ERbeta ligands. Part 5: synthesis and structure-activity relationships of a series of 4'-hydroxyphenyl-aryl-carbaldehyde oxime derivatives

21 January 2018

1 reference

The discovery of tetrahydrofluorenones as a new class of estrogen receptor beta-subtype selective ligands

21 January 2018

1 reference

Benzopyrans are selective estrogen receptor beta agonists with novel activity in models of benign prostatic hyperplasia

21 January 2018

1 reference

Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 2: structure-activity relationship studies on the benzopyran scaffold

21 January 2018

1 reference

Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 3: synthesis of cyclopentanone and cyclohexanone intermediates for C-ring modification

21 January 2018

1 reference

Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 4: functionalization of the benzopyran A-ring

21 January 2018

1 reference

Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 5: Combined A- and C-ring structure-activity relationship studies

21 January 2018

1 reference

A comparative QSAR study using CoMFA, HQSAR, and FRED/SKEYS paradigms for estrogen receptor binding affinities of structurally diverse compounds.

21 January 2018

1 reference

Ligand-based identification of environmental estrogens.

21 January 2018

1 reference

Novel variable selection quantitative structure--property relationship approach based on the k-nearest-neighbor principle

21 January 2018

1 reference

The importance of molecular structures, endpoints' values, and predictivity parameters in QSAR research: QSAR analysis of a series of estrogen receptor binders

21 January 2018

1 reference

CoMFA and docking study of novel estrogen receptor subtype selective ligands

21 January 2018

1 reference

Structure-based virtual screening for plant-based ERbeta-selective ligands as potential preventative therapy against age-related neurodegenerative diseases

21 January 2018

1 reference

Pharmacophore and QSAR modeling of estrogen receptor beta ligands and subsequent validation and in silico search for new hits.

21 January 2018

1 reference

In silico prediction of estrogen receptor subtype binding affinity and selectivity using statistical methods and molecular docking with 2-arylnaphthalenes and 2-arylquinolines

21 January 2018

1 reference

QSAR of estrogen receptor modulators: exploring selectivity requirements for ER(alpha) versus ER(beta) binding of tetrahydroisoquinoline derivatives using E-state and physicochemical parameters

21 January 2018

1 reference

Structure-based approach for the study of estrogen receptor binding affinity and subtype selectivity.

21 January 2018

1 reference

Estrogen receptor β ligands: recent advances and biomedical applications.

21 January 2018

1 reference

Activation of estrogen receptor-beta regulates hippocampal synaptic plasticity and improves memory

21 January 2018

1 reference

Oestrogen receptor beta ligand: a novel treatment to enhance endogenous functional remyelination

21 January 2018

1 reference

Neuroprotective and anti-inflammatory effects of estrogen receptor ligand treatment in mice

21 January 2018

1 reference

Predictive QSAR modeling workflow, model applicability domains, and virtual screening

21 January 2018

1 reference

A critical assessment of docking programs and scoring functions

21 January 2018

1 reference

Quantitative Structure-Based Design: Formalism and Application of Receptor-Dependent RD-4D-QSAR Analysis to a Set of Glucose Analogue Inhibitors of Glycogen Phosphorylase

21 January 2018

1 reference

DrugScore meets CoMFA: adaptation of fields for molecular comparison (AFMoC) or how to tailor knowledge-based pair-potentials to a particular protein.

21 January 2018

1 reference

Reliability of comparative molecular field analysis models: effects of data scaling and variable selection using a set of human synovial fluid phospholipase A2 inhibitors.

21 January 2018

1 reference

Prediction of drug binding affinities by comparative binding energy analysis.

21 January 2018

1 reference

The receptor-dependent QSAR paradigm: an overview of the current state of the art.

21 January 2018

1 reference

Receptor dependent multidimensional QSAR for modeling drug--receptor interactions

21 January 2018

1 reference

Whither combine? New opportunities for receptor-based QSAR.

21 January 2018

1 reference

A new structure-based QSAR method affords both descriptive and predictive models for phosphodiesterase-4 inhibitors

21 January 2018

1 reference

Development of improved models for phosphodiesterase-4 inhibitors with a multi-conformational structure-based QSAR method

21 January 2018

1 reference

A novel structure-based multimode QSAR method affords predictive models for phosphodiesterase inhibitors.

21 January 2018

1 reference

21 January 2018

1 reference

Rational selection of training and test sets for the development of validated QSAR models

21 January 2018

1 reference

ART 2: self-organization of stable category recognition codes for analog input patterns.

21 January 2018

1 reference

On two novel parameters for validation of predictive QSAR models.

21 January 2018

1 reference

Benchmarking sets for molecular docking

21 January 2018

1 reference

Novel approach to structure-based pharmacophore search using computational geometry and shape matching techniques

21 January 2018

1 reference

LigandScout: 3-D pharmacophores derived from protein-bound ligands and their use as virtual screening filters

21 January 2018

1 reference

Endocrine therapy of breast cancer

21 January 2018

1 reference

Receptor-based 3D QSAR analysis of estrogen receptor ligands--merging the accuracy of receptor-based alignments with the computational efficiency of ligand-based methods

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.4155/FMC.11.49

1 reference

14 September 2017

1 reference

PubMed ID

21707397