(Q39736685)

14 September 2017

title

Identification of herpes simplex virus type 1 proteins encoded within the first 1.5 kb of the latency-associated transcript (English)

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Herpes simplex virus type 1

14 September 2017

main subject

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Gail Henderson

1

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14 September 2017

Tareq Jaber

2

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14 September 2017

Dale Carpenter

3

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14 September 2017

Steven L Wechsler

4

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14 September 2017

Clinton Jones

5

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14 September 2017

publication date

1 September 2009

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14 September 2017

published in

Journal of NeuroVirology

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14 September 2017

volume

15

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14 September 2017

issue

5-6

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14 September 2017

page(s)

439-448

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https://scigraph.springernature.com/pub.10.3109/13550280903296353

14 September 2017

exact match

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cites work

Establishment and maintenance of HSV latent infection is mediated through correct splicing of the LAT primary transcript

1 reference

12 December 2020

Regulation of caspase 8- and caspase 9-induced apoptosis by the herpes simplex virus type 1 latency-associated transcript

1 reference

12 December 2020

A novel latency-active promoter is contained within the herpes simplex virus type 1 UL flanking repeats.

1 reference

12 December 2020

A protein encoded by the herpes simplex virus (HSV) type 1 2-kilobase latency-associated transcript is phosphorylated, localized to the nucleus, and overcomes the repression of expression from exogenous promoters when inserted into the quiescent HSV

1 reference

12 December 2020

The herpes simplex virus latency-associated transcript is spliced during the latent phase of infection

1 reference

12 December 2020

Methods for detecting the HSV-1 LAT anti-apoptosis activity in virus infected tissue culture cells.

1 reference

12 December 2020

Comprehensive quantification of herpes simplex virus latency at the single-cell level

1 reference

12 December 2020

Persistence and reactivation of bovine herpesvirus 1 in the tonsils of latently infected calves

1 reference

12 December 2020

Experimental investigation of herpes simplex virus latency

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12 December 2020

A herpes simplex virus type 1 latency-associated transcript mutant with increased virulence and reduced spontaneous reactivation

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12 December 2020

Latent herpes simplex virus type 1 transcripts in peripheral and central nervous system tissues of mice map to similar regions of the viral genome

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12 December 2020

Regulation and cell-type-specific activity of a promoter located upstream of the latency-associated transcript of herpes simplex virus type 1.

1 reference

12 December 2020

Analysis of protein expression from within the region encoding the 2.0-kilobase latency-associated transcript of herpes simplex virus type 1

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12 December 2020

Detection and preliminary characterization of herpes simplex virus type 1 transcripts in latently infected human trigeminal ganglia

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12 December 2020

Herpes simplex virus latency-associated transcript encodes a protein which greatly enhances virus growth, can compensate for deficiencies in immediate-early gene expression, and is likely to function during reactivation from virus latency

1 reference

12 December 2020

Herpes simplex virus type 1 latency-associated transcript expression protects trigeminal ganglion neurons from apoptosis

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12 December 2020

Introducing point mutations into the ATGs of the putative open reading frames of the HSV-1 gene encoding the latency associated transcript (LAT) reduces its anti-apoptosis activity

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12 December 2020

The product of ORF O located within the domain of herpes simplex virus 1 genome transcribed during latent infection binds to and inhibits in vitro binding of infected cell protein 4 to its cognate DNA site

1 reference

12 December 2020

Identification of Herpes Simplex Virus Type 1 Latency-Associated Transcript Sequences That both Inhibit Apoptosis and Enhance the Spontaneous Reactivation Phenotype

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12 December 2020

Regions of the herpes simplex virus type 1 latency-associated transcript that protect cells from apoptosis in vitro and protect neuronal cells in vivo

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12 December 2020

Expression of a herpes simplex virus 1 open reading frame antisense to the gamma(1)34.5 gene and transcribed by an RNA 3' coterminal with the unspliced latency-associated transcript.

1 reference

12 December 2020

RNA from an immediate early region of the type 1 herpes simplex virus genome is present in the trigeminal ganglia of latently infected mice

1 reference

12 December 2020

A protein encoded by the bovine herpesvirus 1 open reading frame E gene induces neurite-like morphological changes in mouse neuroblastoma cells and is expressed in trigeminal ganglionic neurons

1 reference

12 December 2020

Mapping of low abundance latency-associated RNA in the trigeminal ganglia of mice latently infected with herpes simplex virus type 1.

1 reference

12 December 2020

Activity of herpes simplex virus type 1 latency-associated transcript (LAT) promoter in neuron-derived cells: evidence for neuron specificity and for a large LAT transcript.

1 reference

12 December 2020

Analysis of cyclins in trigeminal ganglia of calves infected with bovine herpesvirus-1

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12 December 2020

Analysis of bovine trigeminal ganglia following infection with bovine herpesvirus 1

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12 December 2020

The spontaneous reactivation function of the herpes simplex virus type 1 LAT gene resides completely within the first 1.5 kilobases of the 8.3-kilobase primary transcript

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12 December 2020

Virus-induced neuronal apoptosis blocked by the herpes simplex virus latency-associated transcript.

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12 December 2020

A 371-nucleotide region between the herpes simplex virus type 1 (HSV-1) LAT promoter and the 2-kilobase LAT is not essential for efficient spontaneous reactivation of latent HSV-1

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12 December 2020

Stable cell lines expressing high levels of the herpes simplex virus type 1 LAT are refractory to caspase 3 activation and DNA laddering following cold shock induced apoptosis

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12 December 2020

Two herpes simplex virus type 1 latency-active promoters differ in their contributions to latency-associated transcript expression during lytic and latent infections

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12 December 2020

The latency-associated transcript gene of herpes simplex virus type 1 (HSV-1) is required for efficient in vivo spontaneous reactivation of HSV-1 from latency

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12 December 2020

RNA complementary to a herpesvirus alpha gene mRNA is prominent in latently infected neurons

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12 December 2020

The locus encompassing the latency-associated transcript of herpes simplex virus type 1 interferes with and delays interferon expression in productively infected neuroblastoma cells and trigeminal Ganglia of acutely infected mice.

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12 December 2020

The latency-associated promoter of herpes simplex virus type 1 requires a region downstream of the transcription start site for long-term expression during latency.

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12 December 2020

Detection of latency-related viral RNAs in trigeminal ganglia of rabbits latently infected with herpes simplex virus type 1.

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12 December 2020

Comparison of inflammatory infiltrates in trigeminal ganglia of cattle infected with wild-type Bovine herpesvirus 1 versus a virus strain containing a mutation in the LR (latency-related) gene

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12 December 2020

Region of herpes simplex virus type 1 latency-associated transcript sufficient for wild-type spontaneous reactivation promotes cell survival in tissue culture

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12 December 2020

Physical characterization of the herpes simplex virus latency-associated transcript in neurons.

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12 December 2020

Infection with herpes-simplex viruses 1 and 2. 3.

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12 December 2020

The bovine herpesvirus-1 LR ORF2 is critical for this gene's ability to restore the high wild-type reactivation phenotype to a herpes simplex virus-1 LAT null mutant

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12 December 2020

Three herpes simplex virus type 1 latency-associated transcript mutants with distinct and asymmetric effects on virulence in mice compared with rabbits

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12 December 2020

Alphaherpesvirus latency: its role in disease and survival of the virus in nature

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12 December 2020

A gene capable of blocking apoptosis can substitute for the herpes simplex virus type 1 latency-associated transcript gene and restore wild-type reactivation levels

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12 December 2020

The region of the herpes simplex virus type 1 LAT gene that is colinear with the ICP34.5 gene is not involved in spontaneous reactivation.

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12 December 2020

The region of the herpes simplex virus type 1 LAT gene involved in spontaneous reactivation does not encode a functional protein.

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12 December 2020

Cellular FLIP can substitute for the herpes simplex virus type 1 latency-associated transcript gene to support a wild-type virus reactivation phenotype in mice

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12 December 2020

Herpes simplex virus type 1 and bovine herpesvirus 1 latency

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12 December 2020

Latent herpes simplex virus in human trigeminal ganglia. Detection of an immediate early gene "anti-sense" transcript by in situ hybridization

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12 December 2020

The gene that encodes the herpes simplex virus type 1 latency-associated transcript influences the accumulation of transcripts (Bcl-x(L) and Bcl-x(S)) that encode apoptotic regulatory proteins.

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12 December 2020

The herpes simplex virus type 1 locus that encodes the latency-associated transcript enhances the frequency of encephalitis in male BALB/c mice

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12 December 2020

An antigen encoded by the latency-associated transcript in neuronal cell cultures latently infected with herpes simplex virus type 1

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12 December 2020

Expression and splicing of the latency-associated transcripts of herpes simplex virus type 1 in neuronal and non-neuronal cell lines

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12 December 2020

10.3109/13550280903296353

Identifiers

DOI

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Dimensions Publication ID

14 September 2017

1008920306

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Fatcat ID

release_a6x7salmpzgaxnnqhklmqis2ai

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Fatcat

https://api.fatcat.wiki/v0/release/a6x7salmpzgaxnnqhklmqis2ai

24 November 2022

mapped directly with Wikidata item

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