(Q39739043)

14 September 2017

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title

Current issues in thrombosis prevention with antiplatelet drugs (English)

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14 September 2017

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2

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14 September 2017

G de Gaetano

1

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14 September 2017

E Dejana

series ordinal

3

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14 September 2017

J Vermylen

series ordinal

4

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14 September 2017

publication date

1 June 1986

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14 September 2017

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14 September 2017

volume

31

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14 September 2017

issue

6

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14 September 2017

page(s)

517-549

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https://scigraph.springernature.com/pub.10.2165/00003495-198631060-00004

14 September 2017

exact match

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cites work

A pharmacological approach to the inhibition of platelet adhesion and platelet aggregation. Wright-Schulte Lecture.

1 reference

12 December 2020

Cultured human endothelial cells generate tissue factor in response to endotoxin

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12 December 2020

Selective and nonselective inhibition of thromboxane formation

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12 December 2020

Antithrombotic potential of low-dose aspirin

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12 December 2020

Thrombin generation and fibrin formation following injury to rabbit neointima. Studies of vessel wall reactivity and platelet survival

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12 December 2020

Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells

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12 December 2020

Synthesis of prostacyclin from platelet-derived endoperoxides by cultured human endothelial cells

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12 December 2020

A regimen for low-dose aspirin?

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12 December 2020

Increased Prostacyclin Biosynthesis in Patients with Severe Atherosclerosis and Platelet Activation

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12 December 2020

Platelet-membrane fatty acids, platelet aggregation, and thromboxane formation during a mackerel diet

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12 December 2020

The role of sulfinpyrazone in the prevention of arterio-venous shunt thrombosis

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12 December 2020

Investigation on a selective non-prostanoic thromboxane antagonist, BM 13.177, in human platelets

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12 December 2020

The effect of thrombin on platelet accumulation on the vessel wall - influence of heparin and aspirin

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12 December 2020

Platelet and coagulation function in patients with abnormal cardiac valves treated with sulphinpyrazone

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12 December 2020

Aspirin and thromboembolism--a possible dilemma.

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12 December 2020

Membranoproliferative Glomerulonephritis

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12 December 2020

Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin

1 reference

12 December 2020

Trial of combined warfarin plus dipyridamole or aspirin therapy in prosthetic heart valve replacement: Danger of aspirin compared with dipyridamole

1 reference

12 December 2020

Selective cumulative inhibition of platelet thromboxane production by low-dose aspirin in healthy subjects

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12 December 2020

Placebo-controlled double-blind trial of ketanserin in treatment of intermittent claudication

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12 December 2020

Femoral-artery infusion of prostaglandin E 1 in severe peripheral vascular disease

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12 December 2020

Effect of aspirin and sodium salicylate on thrombosis, fibrinolysis, prothrombin time, and platelet survival In rabbits with indwelling aortic catheters

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12 December 2020

Hemodialysis using prostacyclin instead of heparin as the sole antithrombotic agent

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12 December 2020

Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man

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12 December 2020

Delay in primary haemostasis produced by a fish diet without change in local thromboxane A2

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12 December 2020

Aspirin and prophylaxis of thromboembolic complications in patients with substitute heart valves

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12 December 2020

Study of the two pathways for arachidonate oxygenation in blood platelets

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12 December 2020

Prevention of Thrombosis in Patients on Hemodialysis by Low-Dose Aspirin

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12 December 2020

The "aspirin dilemma": new points for discussion.

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12 December 2020

Normal mechanisms of platelet function

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12 December 2020

Arachidonic acid-induced human platelet aggregation and prostaglandin formation

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12 December 2020

Decreased sensitivity of human platelets to PGI2 during long-term intraarterial prostacyclin infusion in patients with peripheral vascular disease--a rebound phenomenon?

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12 December 2020

Platelet and vascular arachidonic acid metabolites: can they help detect a tendency towards thrombosis?

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12 December 2020

Differential effects of dazoxiben, a selective thromboxane-synthase inhibitor, on platelet and renal prostaglandin-endoperoxide metabolism

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12 December 2020

Protein-C: biochemistry, physiology, and clinical implications

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12 December 2020

Blood cell membranes and haemostasis

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12 December 2020

ADP-induced refractory state of platelets in vitro. I. Methodological studies on aggregation in platelet rich plasma

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12 December 2020

Metabolism of inositides and the activation of platelets

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12 December 2020

Potentiation by dazoxiben, a thromboxane synthetase inhibitor, of platelet aggregation inhibitory activity of a thromboxane receptor antagonist and of prostacyclin

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12 December 2020

Prostacyclin is a circulating hormone

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12 December 2020

Platelets and diabetes mellitus

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12 December 2020

Differential inhibition of prostacyclin production and platelet aggregation by aspirin

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12 December 2020

Human platelet size, shape, and related functions in health and disease

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12 December 2020

Antithrombotic therapy with ticlopidine in chronic renal failure patients on maintenance hemodialysis--a multicenter collaborative double blind study

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12 December 2020

The lupus anticoagulant

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12 December 2020

Prostacyclin production by human endothelial and bovine smooth muscle cells in culture. Effect of repeated stimulation with arachidonic acid, thrombin and ionophore A23187

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12 December 2020

Dipyridamole and other phosphodiesterase inhibitors act as antithrombotic agents by potentiating endogenous prostacyclin

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12 December 2020

INHERITED ANTITHROMBIN DEFICIENCY CAUSING THROMBOPHILIA

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12 December 2020

Effects of a selective inhibitor of thromboxane synthetase on human blood platelet behaviour.

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12 December 2020

Aggregation of Human Platelets by Bovine or Human Factor VIII: Role of Carbohydrate Side Chains

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12 December 2020

HEREDITARY DYSFUNCTIONAL PROTEIN C (PROTEIN C BERGAMO) AND THROMBOSIS

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12 December 2020

Platelet function in diabetes mellitus

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12 December 2020

Spontaneous aggregation of blood platelets as a cause of idiopothic thrombosis and recurrent painful toes and fingers

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12 December 2020

The effect of ticlopidine on human endothelial cells in culture

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12 December 2020

Arachidonate metabolism in vascular disorders

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12 December 2020

Low-dose aspirin inhibits platelet and venous cyclo-oxygenase in man

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12 December 2020

Release of prostaglandin F1alpha and F2alpha from superfused platelets: quantitative evaluation of the inhibitory effects of some aspirin-like drugs

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12 December 2020

A thromboxane synthetase inhibitor reorients endoperoxide metabolism in whole blood towards prostacyclin and prostaglandin E2

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12 December 2020

Circulatory and anti-platelet effects of intravenous prostacyclin in healthy men

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12 December 2020

Effect of aspirin on prevention of coronary and cerebrovascular disease in patients with rheumatoid arthritis. A long-term follow-up study

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12 December 2020

Dipyridamole inhibits platelet aggregation in whole blood

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12 December 2020

BM 13.177, A SELECTIVE BLOCKER OF PLATELET AND VESSEL WALL THROMBOXANE RECEPTORS, IS ACTIVE IN MAN

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12 December 2020

Functionally thrombasthenic state in normal platelets following the administration of ticlopidine

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12 December 2020

Mechanisms of Hemostasis and Therapy of Thrombosis: New Concepts Based on the Metabolism of Arachidonic Acid by Platelets and Endothelial Cells

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12 December 2020

Diacylglycerol and phorbol ester stimulate secretion without raising cytoplasmic free calcium in human platelets.

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12 December 2020

Prostaglandins and human platelet aggregation

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12 December 2020

Inhibition of arachidonate-induced human platelet aggregation by a single low oral dose of aspirin in combination with a thromboxane synthase inhibitor

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12 December 2020

Prevention by Ticlopidine of Platelet Consumption During Extracorporeal Circulation for Heart Surgery and Lack of Effect on Operative and Postoperative Bleeding

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12 December 2020

Increased binding of fibrinogen to platelets in diabetes: the role of prostaglandins and thromboxane

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12 December 2020

Indomethacin and urinary excretion of fibrinogen-like material in proliferative glomerulonephritis

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12 December 2020

The Inhibitory Effect of Aspirin on Platelet and Vascular Prostaglandins in Rats cannot be Completely Dissociated

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12 December 2020

Bleeding time in laboratory animals. IV. Effects of prostacyclin, pyrimido-pyrimidine compounds and aspirin in rats

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12 December 2020

Prostacyclin therapy in peripheral arterial disease

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12 December 2020

Role of leukocytes in acute myocardial infarction in anesthetized dogs: relationship to myocardial salvage by anti-inflammatory drugs.

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12 December 2020

Monitoring the entry of new platelets into the circulation after ingestion of aspirin

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12 December 2020

Platelet hyperaggregability occurring during prolonged continuous intravenous infusions of prostacyclin analogue ZK 36374

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12 December 2020

Effects of BM 13.177, a new antiplatelet drug in patients with atheroscleortic disease

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12 December 2020

Platelet thromboxane synthetase inhibitors with low doses of aspirin: possible resolution of the "aspirin dilemma".

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12 December 2020

Drug-induced inhibition of platelet function delays progression of peripheral occlusive arterial disease. A prospective double-blind arteriographically controlled trial

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12 December 2020

A randomized, placebo controlled trial of prostacyclin (PGI2) in peripheral arterial disease

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12 December 2020

Interaction between fibrinogen and cultured endothelial cells. Induction of migration and specific binding

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12 December 2020

Prevention of thromboembolism using aspirin after mitral valve replacement with porcine bioprosthesis

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12 December 2020

Glomerular prostaglandin and thromboxane synthesis in rat nephrotoxic serum nephritis. Effects on renal hemodynamics

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12 December 2020

Rapid inactivation of cyclooxygenase activity after stimulation of intact platelets

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12 December 2020

The effect of clinical prostacyclin infusions in advanced arterial disease on platelet function and plasma 6-keto PGF1 alpha levels.

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12 December 2020

Influence of aspirin and dipyridamole on patency of coronary artery bypass grafts

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12 December 2020

A pharmacokinetic and platelet function study of the combined administration of metoprolol and sulfinpyrazone to healthy volunteers

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12 December 2020

Aspirin after myocardial infarction

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12 December 2020

The effect of aspirin inhibition of PGI2 production on platelet adherence to normal and damaged rabbit aortae

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12 December 2020

Clinical prospects for a thromboxane synthetase inhibitor. A Pfizer Central Research Symposium--26th-27th March, 1982

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12 December 2020

Vascular injury: platelets and smooth muscle cell response

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12 December 2020

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12 December 2020

Methods for detection of hypersensitive platelets. Philadelphia, June 1977

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12 December 2020

Cyclooxygenase inhibition, platelet function, and metabolite formation during chronic sulfinpyrazone dosing

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12 December 2020

Antithrombotic therapy in coronary artery disease

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12 December 2020

Evidence for a direct stimulatory effect of prostacyclin on renin release in man.

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12 December 2020

Improved aortocoronary bypass patency by low-dose aspirin (100 mg daily). Effects on platelet aggregation and thromboxane formation

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12 December 2020

INTERMITTENT EPOPROSTENOL (PROSTACYCLIN) INFUSION IN PATIENTS WITH RAYNAUD'S SYNDROME

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12 December 2020

Pharmacologic Control of Thromboembolic Complications of Cardiac-Valve Replacement

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12 December 2020

Vessel injury, platelet adherence, and platelet survival

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12 December 2020

The release of platelet-activating factor from human endothelial cells in culture

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12 December 2020

Endogenous prostacyclin biosynthesis and platelet function during selective inhibition of thromboxane synthase in man.

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12 December 2020

Antiplatelet drugs and thrombosis prevention: ticlopidine in perspective

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12 December 2020

Platelet alpha-granule proteins: studies on release and subcellular localization

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12 December 2020

Familial protein S deficiency is associated with recurrent thrombosis

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12 December 2020

Pharmacology of platelet inhibition in humans: implications of the salicylate-aspirin interaction

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12 December 2020

Interaction of coagulation factor Xa with human platelets

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12 December 2020

Aspirin kinetics and platelet aggregation in man

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12 December 2020

Vascular endothelial and smooth muscle cells in culture selectively release adenine nucleotides

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12 December 2020

13-Azaprostanoic acid: a specific antagonist of the human blood platelet thromboxane/endoperoxide receptor

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12 December 2020

EFFECT OF FIBRINOGEN ON THE AGGREGATION OF PLATELETS BY ADENOSINE DIPHOSPHATE

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12 December 2020

Platelet protection and heparin sparing with prostacyclin during regular dialysis therapy

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12 December 2020

Prostaglandins as Inhibitors of Human Platelet Aggregation

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12 December 2020

Arterial thrombosis, intrauterine death and "lupus" antiocoagulant: detection of immunoglobulin interfering with prostacyclin formation

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12 December 2020

Aspirin as an Antithrombotic Medication

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12 December 2020

Platelet coagulant activities and hemostasis: a hypothesis

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12 December 2020

Endogenous prostacyclin contributes to the efficacy of a thromboxane synthetase inhibitor for preventing coronary artery thrombosis

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12 December 2020

Platelet-mediated vascular contractions: inhibition of the serotonergic component by ketanserin

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12 December 2020

The binding of fibrinogen to its platelet receptor

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12 December 2020

Congenital deficiency of thromboxane and prostacyclin

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12 December 2020

Production of phosphoinositide-derived messengers

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12 December 2020

Synthesis of ciloprost (ZK 36 374): a chemically stable and biologically potent prostacyclin analog

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12 December 2020

12S,20-dihydroxyicosatetraenoic acid: a new icosanoid synthesized by neutrophils from 12S-hydroxyicosatetraenoic acid produced by thrombin- or collagen-stimulated platelets

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12 December 2020

"Lupus" anticoagulant and inhibition of prostacyclin formation in patients with repeated abortion, intrauterine growth retardation and intrauterine death

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12 December 2020

Vascular relaxing activity and stability studies of 10,10-difluoro-13,14-dehydroprostacyclin

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12 December 2020

Thromboxane synthase inhibition combined with thromboxane receptor blockade: a step forward in antithrombotic strategy?

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12 December 2020

Deficiency of protein C in congenital thrombotic disease

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12 December 2020

Cumulative inhibitory effect of low-dose aspirin on vascular prostacyclin and platelet thromboxane production in patients with atherosclerosis

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12 December 2020

Prostacyclin--powerful, yes: but is it useful?

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12 December 2020

Plasma levels of salicylate and aspirin in healthy volunteers: relevance to drug interaction on platelet function

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12 December 2020

Nitroglycerin stimulates synthesis of prostacyclin by cultured human endothelial cells

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12 December 2020

Blood flow reductions in stenosed canine coronary arteries: vasospasm or platelet aggregation?

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12 December 2020

9,11-epoxyiminoprosta-5,13-dienoic acid is a thromboxane A2 antagonist in human platelets

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12 December 2020

The metabolism of arachidonic acid by platelets in nephrotic syndrome

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12 December 2020

Effects of sulfinpyrazone on early graft closure after myocardial revascularization

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12 December 2020

Platelets, prostaglandins and thrombotic disorders

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12 December 2020

The biologic background to some therapeutic uses of aspirin

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12 December 2020

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12 December 2020

Studies of platelet and fibrinogen kinetics in patients with prosthetic heart valves

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12 December 2020

Eicosapentaenoic acid and prevention of thrombosis and atherosclerosis?

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12 December 2020

Carbacyclin--a potent stable prostacyclin analogue for the inhibition of platelet aggregation

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12 December 2020

Transient ischemic attacks and aspirin, stroke and death; negative studies and Type II error

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12 December 2020

The inhibition of cyclo-oxygenase of rabbit platelets by aspirin is prevented by salicylic acid and by phenanthrolines

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12 December 2020

Inhibition of platelet prostaglandin synthetase by oral aspirin

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12 December 2020

The influence on platelet aggregation of drugs that affect the accumulation of adenosine 3':5'-cyclic monophosphate in platelets

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12 December 2020

Identification in vitro of an endothelial cell surface cofactor for antithrombin III. Parallel studies with isolated perfused rat hearts and microcarrier cultures of bovine endothelium

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12 December 2020

Experience with prostacyclin in cardiopulmonary bypass in dog and man

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12 December 2020

Latent tissue plasminogen activator produced by human endothelial cells in culture: evidence for an enzyme-inhibitor complex

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12 December 2020

PROLONGING PROSTACYCLIN PRODUCTION BY NAFAZATROM OR DIPYRIDAMOLE

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12 December 2020

Inhibitory role of the endothelium in the response of isolated coronary arteries to platelets

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12 December 2020

Effect of aspirin on thrombin-induced adherence of platelets to cultured cells from the blood vessel wall

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12 December 2020

Thromboxane synthetase inhibition as antithrombotic strategy

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12 December 2020

Aspirin to prevent arterial thrombosis

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12 December 2020

Factors influencing platelet function: adhesion, release, and aggregation.

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12 December 2020

Evidence that Vascular Endothelial Cells Can Induce the Retraction of Fibrin Clots

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12 December 2020

"But will it help my patients with myocardial infarction?" The implications of recent trials for everyday country folk

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12 December 2020

Prolongation of bleeding time and inhibition of platelet aggregation by low-dose acetylsalicylic acid in patients with cerebrovascular disease

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12 December 2020

Effect of thromboxane synthetase inhibitors on platelet function: enhancement by inhibition of phosphodiesterase

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12 December 2020

Indomethacin and Platelet Aggregation in Chronic Glomerulonephritis: Existence of Non-responders

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12 December 2020

The inverse relation between fish consumption and 20-year mortality from coronary heart disease

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12 December 2020

Sulphinpyrazone in post-myocardial infarction. Report from the Anturan Reinfarction Italian Study

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12 December 2020

Prevention of arterial thromboembolism with acetylsalicylic acid. A controlled clinical study in patients with aortic ball valves

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12 December 2020

The role of protein kinase C in cell surface signal transduction and tumour promotion

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12 December 2020

Sulfinpyrazone: a review of its pharmacological properties and therapeutic use.

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12 December 2020

Serum albumin enhances the impairment of platelet aggregation with thromboxane synthase inhibition by increasing the formation of prostaglandin D2.

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12 December 2020

Anticoagulants in coronary heart disease--retrospect and prospect

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12 December 2020

The blood platelet release reaction

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12 December 2020

Indobufen, a new inhibitor of platelet aggregation. Studies in guinea pigs

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12 December 2020

Indomethacin treatment of membranoproliferative and lobular glomerulonephritis

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12 December 2020

On the regulation and control of fibrinolysis. Edward Kowalski Memorial Lecture

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12 December 2020

Fetal survival after prednisone suppression of maternal lupus-anticoagulant

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12 December 2020

Protective effects of aspirin against acute myocardial infarction and death in men with unstable angina. Results of a Veterans Administration Cooperative Study

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12 December 2020

Inhibition of human platelet thromboxane generation by aspirin in the absence of measurable drug levels in peripheral blood

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12 December 2020

Ticlopidine: a promise for the prevention and treatment of thrombosis and its complications

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12 December 2020

Prospective trial of warfarin and dipyridamole in patients with membranoproliferative glomerulonephritis

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12 December 2020

EPOPROSTENOL (PROSTACYCLIN) AND SEVERE ARTERIAL DISEASE

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12 December 2020

Effects of platelet inhibition on myocardial ischaemia

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12 December 2020

The relationship between vessel wall injury and venous thrombosis: an experimental study

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12 December 2020

Reduced platelet thromboxane formation in uremia. Evidence for a functional cyclooxygenase defect

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12 December 2020

Anti-platelet activity of beta-adrenergic antagonists: inhibition of thromboxane synthesis and platelet aggregation in patients receiving long-term propranolol treatment

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12 December 2020

Effect of ADP-utilizing enzymes on the arterial bleeding time in rats and rabbits

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12 December 2020

Platelet interaction with damaged rabbit aorta

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12 December 2020

The FDA's critique of the anturane reinfarction trial

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12 December 2020

Effects of platelet-modifying drugs on arterial thromboembolism in baboons. Aspirin potentiates the antithrombotic actions of dipyridamole and sulfinpyrazone by mechanism(s) independent of platelet cyclooxygenase inhibition

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12 December 2020

Long-term and short-term beta-blockade after myocardial infarction

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12 December 2020

Are agents affecting platelet functions clinically useful?

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12 December 2020

Platelet survival in patients with rheumatic heart disease

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12 December 2020

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12 December 2020

Lack of synergism between dazoxiben and dipyridamole following administration to man

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12 December 2020

A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro

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12 December 2020

Salicylate-aspirin interaction in the rat. Evidence that salicylate accumulating during aspirin administration may protect vascular prostacyclin from aspirin-induced inhibition

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12 December 2020

Differential salicylate-aspirin interaction on vascular prostacyclin and platelet thromboxane synthesis in patients undergoing saphenectomy

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12 December 2020

Platelet-aggregation response to single or paired aggregating stimuli after low-dose aspirin

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12 December 2020

Properties of human asialo-factor VIII. A ristocetin-independent platelet-aggregating agent

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12 December 2020

Acceleration of thrombin-antithrombin complex formation in rat hindquarters via heparinlike molecules bound to the endothelium

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12 December 2020

Thrombosthenin, the contractile protein of blood platelets. New facts and problems.

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12 December 2020

Activation of factor IX bound to cultured bovine aortic endothelial cells

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12 December 2020

Inhibition of human platelet cyclo-oxygenase activity by sulfinpyrazone and three of its metabolites

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12 December 2020

Is prostacyclin a physiologically important circulating anti-platelet agent?

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12 December 2020

URAEMIC BLEEDING: ROLE OF ANAEMIA AND BENEFICIAL EFFECT OF RED CELL TRANSFUSIONS

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12 December 2020

Pharmacologic inhibition of thromboxane synthetase and platelet aggregation: modulatory role of cyclooxygenase products

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12 December 2020

Mechanism of action of dipyridamole

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12 December 2020

Activation and inhibition of blood platelet adenylate cyclase by adenosine or by 2-chloroadenosine

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12 December 2020

Manipulation of the local thromboxane and prostacyclin balance in vivo by the antithrombotic compounds dazoxiben, acetylsalicylic acid and nafazatrom

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12 December 2020

Stimulation of prostacyclin by dipyridamole

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12 December 2020

Cytoplasmic free Ca2+ in human platelets: Ca2+ thresholds and Ca-independent activation for shape-change and secretion

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12 December 2020

Effect of dipyridamole and aspirin on late vein-graft patency after coronary bypass operations

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12 December 2020

Clinical aspects of the arachidonic acid--thromboxane pathway

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12 December 2020

Inhibition of thromboxane synthetase does not necessarily prevent platelet aggregation

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12 December 2020

Prostacyclin to prevent platelet activation during charcoal haemoperfusion in fulminant hepatic failure

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12 December 2020

Aspirin and recurrent painful toes and fingers in thrombocythaemia.

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12 December 2020

Effective and fibrin-specific clot lysis by a zymogen precursor form of urokinase (pro-urokinase). A study in vitro and in two animal species

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12 December 2020

Cyclic nucleotides control a system which regulates Ca2+ sensitivity of platelet secretion

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12 December 2020

Increased glomerular thromboxane synthesis as a possible cause of proteinuria in experimental nephrosis

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12 December 2020

A Platelet-Inhibitor-Drug Trial in Coronary-Artery Bypass Operations

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12 December 2020

PHARMACOLOGY OF ANTIPLATELET DRUGS AND CLINICAL TRIALS ON THROMBOSIS PREVENTION: A DIFFICULT LINK

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12 December 2020

Suloctidil: Relationship between pharmacokinetics and antithrombotic effect

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12 December 2020

Effects of a selective inhibitor of thromboxane synthetase (OKY-1581) in humans

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12 December 2020

Amplification of primary response of human platelets to platelet-activating factor: aspirin-sensitive and aspirin-insensitive pathways

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12 December 2020

10.2165/00003495-198631060-00004

Identifiers

DOI

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Dimensions Publication ID

14 September 2017

1031476016

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