(Q39744992)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20125118%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

The temporal relationship between ABCB1 promoter hypomethylation, ABCB1 expression and acquisition of drug resistance (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20125118%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

3

1 reference

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17 January 2020

author name string

K Reed

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20125118%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

S L Hembruff

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20125118%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

A M Parissenti

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20125118%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

publication date

2 February 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20125118%20AND%20SRC:MED&resulttype=core&format=json

The Pharmacogenomics Journal

17 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20125118%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20125118%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20125118%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

489-504

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20125118%20AND%20SRC:MED&resulttype=core&format=json

The rise of DNA methylation and the importance of chromatin on multidrug resistance in cancer.

17 January 2020

cites work

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Overview: ABC transporters and human disease

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Demethylation of the human MDR1 5' region accompanies activation of P-glycoprotein expression in a HL60 multidrug resistant subline

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The establishment of two paclitaxel-resistant prostate cancer cell lines and the mechanisms of paclitaxel resistance with two cell lines

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MDR1 promoter hypermethylation in MCF-7 human breast cancer cells: changes in chromatin structure induced by treatment with 5-Aza-cytidine

21 January 2018

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A case study in misidentification of cancer cell lines: MCF-7/AdrR cells (re-designated NCI/ADR-RES) are derived from OVCAR-8 human ovarian carcinoma cells

21 January 2018

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Role of DNA hypomethylation in the development of the resistance to doxorubicin in human MCF-7 breast adenocarcinoma cells

21 January 2018

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Genetic and epigenetic modeling of the origins of multidrug-resistant cells in a human sarcoma cell line

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Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs

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Role of drug transporters and drug accumulation in the temporal acquisition of drug resistance

21 January 2018

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Induction of 1C aldoketoreductases and other drug dose-dependent genes upon acquisition of anthracycline resistance

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Cross-resistance studies of isogenic drug-resistant breast tumor cell lines support recent clinical evidence suggesting that sensitivity to paclitaxel may be strongly compromised by prior doxorubicin exposure

21 January 2018

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Hypermethylation of the ABCB1 downstream gene promoter accompanies ABCB1 gene amplification and increased expression in docetaxel-resistant MCF-7 breast tumor cells

21 January 2018

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Post-transcriptional regulation of P-glycoprotein expression in cancer cell lines.

21 January 2018

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P-glycoprotein (MDR1) expression in leukemic cells is regulated at two distinct steps, mRNA stabilization and translational initiation

21 January 2018

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Regional activation of chromosomal arm 7q with and without gene amplification in taxane-selected human ovarian cancer cell lines

21 January 2018

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The MDR1/ABCB1 regional amplification in large inverted repeats with asymmetric sequences and microhomologies at the junction sites

21 January 2018

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Gene amplification and expression in lung cancer cells with acquired paclitaxel resistance

21 January 2018

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Preferential expression of a mutant allele of the amplified MDR1 (ABCB1) gene in drug-resistant variants of a human sarcoma

21 January 2018

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Comparison of bisulfite sequencing PCR with pyrosequencing for measuring differences in DNA methylation

21 January 2018

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Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation

21 January 2018

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DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.

21 January 2018

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Allele-specific gene expression patterns in primary leukemic cells reveal regulation of gene expression by CpG site methylation

21 January 2018

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21 January 2018

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Transcriptional regulation of ABC drug transporters

21 January 2018

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Transcriptional regulation of MDR genes

21 January 2018

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Transcriptional activation of the MDR1 gene by UV irradiation. Role of NF-Y and Sp1.

21 January 2018

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21 January 2018

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Increased expression and DNA-binding activity of transcription factor Sp1 in doxorubicin-resistant HL-60 leukemia cells

21 January 2018

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Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1.

21 January 2018

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21 January 2018

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Identification and Characterization of Three DNA-binding Proteins on the Promoter of the Human MDRl Gene in Drug-sensitive and -resistant Cells

21 January 2018

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Transcriptional repression by p53 through direct binding to a novel DNA element

21 January 2018

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Identification and characterization of the MDR1 promoter-enhancing factor 1 (MEF1) in the multidrug resistant HL60/VCR human acute myeloid leukemia cell line

21 January 2018

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