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Genotoxic stress causes the accumulation of the splicing regulator Sam68 in nuclear foci of transcriptionally active chromatin.
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Europe PubMed Central
PMC publication ID
2875014
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20110258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
title
Genotoxic stress causes the accumulation of the splicing regulator Sam68 in nuclear foci of transcriptionally active chromatin
(English)
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stated in
Europe PubMed Central
PMC publication ID
2875014
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20110258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
main subject
genotoxicity
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inferred from title
author
Raffaele Geremia
series ordinal
2
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Europe PubMed Central
PMC publication ID
2875014
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20110258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Claudio Sette
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2875014
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20110258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
author name string
Roberta Busà
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
2875014
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20110258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
language of work or name
English
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publication date
27 January 2010
1 reference
stated in
Europe PubMed Central
PMC publication ID
2875014
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20110258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
published in
Nucleic Acids Research
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Europe PubMed Central
PMC publication ID
2875014
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20110258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
volume
38
1 reference
stated in
Europe PubMed Central
PMC publication ID
2875014
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20110258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
issue
9
1 reference
stated in
Europe PubMed Central
PMC publication ID
2875014
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20110258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
page(s)
3005-3018
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Europe PubMed Central
PMC publication ID
2875014
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20110258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
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Sam68 regulates translation of target mRNAs in male germ cells, necessary for mouse spermatogenesis
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Phase I study of ixabepilone, mitoxantrone, and prednisone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel-based therapy: a study of the department of defense prostate cancer clinical trials consort
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Suppression of HIV-1 Nef translation by Sam68 mutant-induced stress granules and nef mRNA sequestration
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Splicing and splice factor SRp55 participate in the response to DNA damage by changing isoform ratios of target genes
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Transcription of Satellite III non-coding RNAs is a general stress response in human cells
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14 September 2017
Subcellular distribution of human RDM1 protein isoforms and their nucleolar accumulation in response to heat shock and proteotoxic stress
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14 September 2017
The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x
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14 September 2017
The RNA-binding protein Sam68 contributes to proliferation and survival of human prostate cancer cells
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PubMed Central
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14 September 2017
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14 September 2017
Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATR.
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14 September 2017
hnRNP A1 relocalization to the stress granules reflects a role in the stress response.
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14 September 2017
The connection between splicing and cancer.
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14 September 2017
Unbalanced alternative splicing and its significance in cancer
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PubMed Central
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14 September 2017
Cyclin D1b variant influences prostate cancer growth through aberrant androgen receptor regulation
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14 September 2017
Regulation of CD44 alternative splicing by SRm160 and its potential role in tumor cell invasion
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14 September 2017
The human SWI/SNF subunit Brm is a regulator of alternative splicing
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14 September 2017
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14 September 2017
BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II.
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14 September 2017
Structural and functional characterization of noncoding repetitive RNAs transcribed in stressed human cells
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14 September 2017
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14 September 2017
ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions
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14 September 2017
Tr-kit promotes the formation of a multimolecular complex composed by Fyn, PLCgamma1 and Sam68.
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reference URL
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14 September 2017
Sam68, the KH domain-containing superSTAR.
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PubMed Central
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14 September 2017
Mechanisms of alternative pre-messenger RNA splicing
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14 September 2017
ATM and related protein kinases: safeguarding genome integrity
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14 September 2017
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14 September 2017
Sam68 enhances the cytoplasmic utilization of intron-containing RNA and is functionally regulated by the nuclear kinase Sik/BRK.
1 reference
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14 September 2017
Signal-dependent regulation of splicing via phosphorylation of Sam68
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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14 September 2017
Stress granules: sites of mRNA triage that regulate mRNA stability and translatability
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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14 September 2017
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.
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14 September 2017
Stress-induced nuclear bodies are sites of accumulation of pre-mRNA processing factors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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14 September 2017
Regulation of alternative pre-mRNA splicing by the ERK MAP-kinase pathway
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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14 September 2017
Glycogen synthase kinase 3beta and extracellular signal-regulated kinase inactivate heat shock transcription factor 1 by facilitating the disappearance of transcriptionally active granules after heat shock
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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14 September 2017
DNA damage regulates alternative splicing through inhibition of RNA polymerase II elongation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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14 September 2017
Cancer-associated regulation of alternative splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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14 September 2017
Cyclin D1b is aberrantly regulated in response to therapeutic challenge and promotes resistance to estrogen antagonists
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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14 September 2017
The early response to DNA damage can lead to activation of alternative splicing activity resulting in CD44 splice pattern changes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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14 September 2017
Genotoxic stress induces coordinately regulated alternative splicing of the p53 modulators MDM2 and MDM4.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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14 September 2017
Topoisomerase I and II inhibitors control caspase-2 pre-messenger RNA splicing in human cells
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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14 September 2017
Transcriptional activation of a constitutive heterochromatic domain of the human genome in response to heat shock.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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14 September 2017
Dynamic relocation of transcription and splicing factors dependent upon transcriptional activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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25 September 2017
CD44: structure, function, and association with the malignant process.
2 references
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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25 September 2017
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1093%2FNAR%2FGKQ004
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21 January 2018
The nuclear RNA-binding protein Sam68 translocates to the cytoplasm and associates with the polysomes in mouse spermatocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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15 June 2018
Stress-induced transcription of satellite III repeats.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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15 June 2018
Differentiation-dependent chromatin alterations precede and accompany transcription of immunoglobulin light chain genes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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15 June 2018
A method for mapping the distributions of modified and variant histones among mono- and polynucleosomes
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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15 June 2018
Nuclear stress bodies: a heterochromatin affair?
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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20 August 2018
STAT3 is enriched in nuclear bodies
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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20 August 2018
DNA damage induced by DNA topoisomerase I- and topoisomerase II-inhibitors detected by histone H2AX phosphorylation in relation to the cell cycle phase and apoptosis
1 reference
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PubMed Central
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20 August 2018
c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for mitoxantrone- and anisomycin-induced apoptosis in HL-60 cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014
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20 August 2018
Prognostic significance of CD44v5 expression in human thymic epithelial neoplasms
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20110258
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/NAR/GKQ004
1 reference
stated in
Europe PubMed Central
PMC publication ID
2875014
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20110258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
PMC publication ID
2875014
1 reference
stated in
Europe PubMed Central
PMC publication ID
2875014
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20110258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
PubMed publication ID
20110258
1 reference
stated in
Europe PubMed Central
PMC publication ID
2875014
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20110258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
ResearchGate publication ID
41173562
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