(Q39751188)

14 September 2017

title

Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine (English)

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14 September 2017

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GOA release 2020-03-11

Porcupine Dmel_CG6205

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GOA release 2020-03-11

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Linda Zhai

1

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14 September 2017

Deepti Chaturvedi

series ordinal

2

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14 September 2017

Susan Cumberledge

series ordinal

3

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14 September 2017

language of work or name

English

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publication date

27 May 2004

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Journal of Biological Chemistry

14 September 2017

published in

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14 September 2017

volume

279

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14 September 2017

issue

32

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14 September 2017

page(s)

33220-33227

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Wnts as morphogens? The view from the wing of Drosophila

14 September 2017

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Wnt proteins are lipid-modified and can act as stem cell growth factors

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Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog

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The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing

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The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family

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Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm

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Drosophila segment polarity gene product porcupine stimulates the posttranslational N-glycosylation of wingless in the endoplasmic reticulum

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Hsp90 interactions and acylation target the G protein Galpha 12 but not Galpha 13 to lipid rafts

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21 January 2018

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Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan

21 January 2018

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A freely diffusible form of Sonic hedgehog mediates long-range signalling

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M403407200

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14 September 2017

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