(Q39753803)

14 September 2017

title

Epigenetic inactivation and tumor suppressor activity of HAI-2/SPINT2 in gastric cancer (English)

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14 September 2017

Wenjie Dong

1

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14 September 2017

Xiaobing Chen

2

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14 September 2017

Jing Xie

3

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14 September 2017

Pinghu Sun

4

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14 September 2017

Yunlin Wu

5

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14 September 2017

language of work or name

English

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publication date

1 October 2010

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International Journal of Cancer

14 September 2017

published in

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14 September 2017

volume

127

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14 September 2017

issue

7

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14 September 2017

page(s)

1526-1534

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Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor

14 September 2017

cites work

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Hepatocyte growth factor/scatter factor-induced intracellular signalling

21 January 2018

1 reference

An epigenetic genome-wide screen identifies SPINT2 as a novel tumor suppressor gene in pediatric medulloblastoma

21 January 2018

1 reference

Reduced expression of hepatocyte growth factor activator inhibitor type-2/placental bikunin (HAI-2/PB) in human glioblastomas: implication for anti-invasive role of HAI-2/PB in glioblastoma cells

21 January 2018

1 reference

Evaluation of hepatocyte growth factor activator inhibitor expression in normal and malignant colonic mucosa

21 January 2018

1 reference

The hepatocyte growth factor regulatory factors in human breast cancer

21 January 2018

1 reference

c-Met and hepatocyte growth factor: potential as novel targets in cancer therapy

21 January 2018

1 reference

Frequent amplification of the c-met gene in scirrhous type stomach cancer.

21 January 2018

1 reference

Absence of tpr-met and expression of c-met in human gastric mucosa and carcinoma.

21 January 2018

1 reference

Inhibition of c-Met and prevention of spontaneous metastatic spreading by the 2-indolinone RPI-1.

21 January 2018

1 reference

Suppression of tumor growth, invasion and angiogenesis of human gastric cancer by adenovirus-mediated expression of NK4.

21 January 2018

1 reference

SU5416 is a potent inhibitor of hepatocyte growth factor receptor (c-Met) and blocks HGF-induced invasiveness of human HepG2 hepatoma cells

21 January 2018

1 reference

Absence of cyclin D2 expression is associated with promoter hypermethylation in gastric cancer

21 January 2018

1 reference

Frequent loss of expression without sequence mutations of the DCC gene in primary gastric cancer

21 January 2018

1 reference

Aberrant methylation of p16 predicts candidates for 5-fluorouracil-based adjuvant therapy in gastric cancer patients

21 January 2018

1 reference

Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer

21 January 2018

1 reference

Effects of Helicobacter pylori eradication on methylation status of E-cadherin gene in noncancerous stomach.

21 January 2018

1 reference

Tumor suppressor activity and epigenetic inactivation of hepatocyte growth factor activator inhibitor type 2/SPINT2 in papillary and clear cell renal cell carcinoma

21 January 2018

1 reference

Functional epigenomics approach to identify methylated candidate tumour suppressor genes in renal cell carcinoma

21 January 2018

1 reference

Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers.

21 January 2018

1 reference

Hepatocyte growth factor activation inhibitors (HAI-1 and HAI-2) regulate HGF-induced invasion of human breast cancer cells

21 January 2018

1 reference

A Kunitz-type protease inhibitor, bikunin, inhibits ovarian cancer cell invasion by blocking the calcium-dependent transforming growth factor-beta 1 signaling cascade

21 January 2018

1 reference

Suppression of invasion and peritoneal carcinomatosis of ovarian cancer cell line by overexpression of bikunin

21 January 2018

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Genetic downregulation of pregnancy-associated plasma protein-A (PAPP-A) by bikunin reduces IGF-I-dependent Akt and ERK1/2 activation and subsequently reduces ovarian cancer cell growth, invasion and metastasis

21 January 2018

1 reference

Therapeutic efficacy of once-daily oral administration of a Kunitz-type protease inhibitor, bikunin, in a mouse model and in human cancer

21 January 2018

1 reference

Overexpression of a hybrid gene consisting of the amino-terminal fragment of urokinase and carboxyl-terminal domain of bikunin suppresses invasion and migration of human ovarian cancer cells in vitro

21 January 2018

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Bikunin plus paclitaxel markedly reduces tumor burden and ascites in mouse model of ovarian cancer

21 January 2018

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Showering c-MET-dependent cancers with drugs

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.25161

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release_qct4pvs2kbarjaeqruzdgixl5i

14 September 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/qct4pvs2kbarjaeqruzdgixl5i

mapped directly with Wikidata item

24 November 2022

based on heuristic

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