(Q39761046)

14 September 2017

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title

Intravenous anaesthetic agents. Pharmacokinetic-pharmacodynamic relationships (English)

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14 September 2017

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B N Swerdlow

1

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14 September 2017

F O Holley

series ordinal

2

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14 September 2017

publication date

1 February 1987

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Clinical Pharmacokinetics

14 September 2017

published in

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14 September 2017

volume

12

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14 September 2017

issue

2

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14 September 2017

page(s)

79-110

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Comparative pharmacokinetics of fentanyl and alfentanil.

14 September 2017

cites work

1 reference

12 December 2020

Kinetics of drug action in disease states. IV. Effect of pregnancy on phenobarbital concentrations at onset of loss of righting reflex in rats.

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12 December 2020

The hemodynamic consequences of high-dose methohexital anesthesia in humans

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12 December 2020

Thiopentone sensitivity in young and elderly women.

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12 December 2020

Pharmacodynamic modeling of thiopental anesthesia

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12 December 2020

Understanding the dose-effect relationship: clinical application of pharmacokinetic-pharmacodynamic models

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12 December 2020

Clinical pharmacokinetics of the non-depolarising muscle relaxants

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12 December 2020

Effect of preanaesthetic medication on etomidate

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12 December 2020

The Pharmacokinetics of Sufentanil in Surgical Patients

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12 December 2020

Distribution and Biotransformation of Succinylcholine

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12 December 2020

The minimum effective analgetic blood concentration of pethidine in patients with intractable pain

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12 December 2020

[A microprocessor controlled infusion scheme for midazolam to achieve constant plasma levels (author's transl)]

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12 December 2020

Kinetic of pharmacalogic activity of succinylcholine in man

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12 December 2020

Clinical pharmacokinetics applied to patients with intractable pain: studies with pethidine

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12 December 2020

Metocurine requirements and plasma concentrations in burned paediatric patients.

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12 December 2020

Patient-controlled analgesic therapy, Part II: Individual analgesic demand and analgesic plasma concentrations of pethidine in postoperative pain.

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12 December 2020

Multiple intramuscular injections: a major source of variability in analgesic response to meperidine.

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12 December 2020

Influence of moderate alcohol intake on wakening plasma thiopental concentration.

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12 December 2020

Clinical Pharmacokinetics of Diazepam

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12 December 2020

[Myocardial perfusion and myocardial oxygen consumption in patients during the induction of anesthesia using dehydrobenzperidol-fentanyl or ketamine]

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12 December 2020

Comparison of a New Formulation of Etomidate with Thiopental—Side Effects and Awakening Times

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12 December 2020

A clinical assessment of the use of etomidate in children

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12 December 2020

Safety and efficacy of atracurium in adolescents and children anesthetized with halothane.

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12 December 2020

The Clinical Pharmacology of Meperidine—Comparison of Routes of Administration

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12 December 2020

Pharmacokinetics of atracurium besylate in healthy patients (after a single i.v. bolus dose)

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12 December 2020

The effects of a benzodiazepine antagonist Ro 15-1788 in the presence of stable concentrations of midazolam.

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12 December 2020

Pharmacokinetics of thiopentone: effects of enflurane and nitrous oxide anaesthesia and surgery

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12 December 2020

Fentanyl infusion anesthesia for aortocoronary bypass surgery: plasma levels and hemodynamic response.

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12 December 2020

Pharmacokinetics of Org NC45 (norcuron) in patients with and without renal failure

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12 December 2020

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12 December 2020

Relationship between diazepam dose, plasma level, age, and central nervous system depression

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12 December 2020

Morphine kinetics in children

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12 December 2020

A Pharmacokinetic Approach to Postoperative Pain: Continuous Infusion of Pethidine

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12 December 2020

Clinical, Electroencephalographic, and Pharmacokinetic Studies of a Water-soluble Benzodiazepine, Midazolam Maleate

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12 December 2020

Methohexitone and thiopentone. Response to stimuli and incidence of some side effects

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12 December 2020

Comparison of the recovery from methohexital and thiopental anesthesia in man.

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12 December 2020

The Effect of Circulation Time on the Neuromuscular Action of Suxamethonium

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12 December 2020

EEG quantitation of narcotic effect: the comparative pharmacodynamics of fentanyl and alfentanil

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12 December 2020

Gastric and biliary excretion of meperidine in man

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12 December 2020

Relative amnesic actions of diazepam, flunitrazepam and lorazepam in man

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12 December 2020

Pharmacokinetics and plasma binding of thiopental. I: Studies in surgical patients

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12 December 2020

Plasma concentrations of alfentanil required to supplement nitrous oxide anesthesia for general surgery.

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12 December 2020

Influence of moderate alcohol intake on thiopental anesthesia.

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12 December 2020

Pharmacokinetics of methohexitone following intravenous infusion in humans

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12 December 2020

Clinical Pharmacokinetics of Oxazepam and Lorazepam

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12 December 2020

Pharmacokinetics of ketamine in man

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12 December 2020

Pharmacokinetics and Pharmacodynamics of d-Tubocurarine during Nitrous Oxide–Narcotic and Halothane Anesthesia in Man

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12 December 2020

The pharmacokinetics of midazolam in man.

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12 December 2020

Anaesthetic induction with alfentanil: comparison with thiopental, midazolam, and etomidate.

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12 December 2020

Effects of aging and liver disease on disposition of lorazepam

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12 December 2020

Pharmacokinetics and pharmacodynamics of d-tubocurarine in infants, children, and adults.

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12 December 2020

Disuse atrophy with resistance to pancuronium.

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12 December 2020

Pharmacodynamics of non-depolarizing neuromuscular blocking agents

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12 December 2020

Meperidine disposition in man: Influence of urinary pH and route of administration

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12 December 2020

Effects of ketamine on canine cerebral blood flow and metabolism: modification by prior administration of thiopental

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12 December 2020

Clinical pharmacology of vecuronium and atracurium

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12 December 2020

Acute tolerance to thiopentone in man.

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12 December 2020

Alfentanil kinetics in the elderly

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12 December 2020

Meperidine kinetics in man; Intravenous injection in surgical patients and volunteers

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12 December 2020

Plasma concentrations and clinical effects of lorazepam after oral administration

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12 December 2020

Seizures induced by methohexital.

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12 December 2020

Drug therapy. Current status of benzodiazepines

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12 December 2020

Etomidate: an ultrashort-acting nonbarbiturate agent for anesthesia induction

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12 December 2020

Methohexital plasma concentrations in children following rectal administration

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12 December 2020

Ketamine kinetics in unmedicated and diazepam-premedicated subjects.

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12 December 2020

Relationship of ventilatory depression to steady-state blood pethidine concentrations.

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12 December 2020

Evidence for a characteristic EEG frequency response to thiopental

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12 December 2020

Morphine pharmacokinetics: GLC assay versus radioimmunoassay

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12 December 2020

Pharmacokinetics of the nondepolarizing neuromuscular relaxants applied to calculation of bolus and infusion dosage regimens

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12 December 2020

The role of body fat in limiting the duration of action of thiopental.

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12 December 2020

The 'induction' dose of thiopentone. A method of study and preliminary illustrative results.

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12 December 2020

Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine

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12 December 2020

Pharmacokinetics and dynamics of muscle relaxants

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12 December 2020

Pharmacokinetics in Intravenous Anaesthetic Practice

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12 December 2020

Neuromuscular effects of vecuronium (ORG NC45) in infants and children during N2O, halothane anesthesia.

1 reference

12 December 2020

Pharmacokinetics and analgesic effect of ketamine in man.

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12 December 2020

Midazolam: pharmacology and uses

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12 December 2020

Pharmacokinetic basis for the dose-dependent decline in the neuromuscular blocking effect of gallamine.

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12 December 2020

Inhibition of Adrenal Steroidogenesis by the Anesthetic Etomidate

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12 December 2020

Pharmacokinetics and the sedative effect of midazolam

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12 December 2020

Increased d-tubocurarine requirement following major thermal injury

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12 December 2020

Narcotic requirements for intravenous anesthesia.

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12 December 2020

Lipid solubility, pharmacokinetics, and the EEG: are you better off today than you were four years ago?

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12 December 2020

Ventilatory depression related to plasma fentanyl concentrations during and after anesthesia in humans.

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12 December 2020

Clinical pharmacokinetics of the newer intravenous anaesthetic agents

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12 December 2020

Ventilatory effects during and after continuous infusion of fentanyl or alfentanil.

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12 December 2020

Morphine binding to human plasma proteins

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12 December 2020

Automated gas chromatography for studies of midazolam pharmacokinetics.

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12 December 2020

Comparative pharmacology of the ketamine isomers. Studies in volunteers

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12 December 2020

Fentanyl's analgesic, respiratory, and cardiovascular actions in relation to dose and plasma concentration in unanesthetized dogs

1 reference

12 December 2020

Kinetics of drug action in disease states. VI. Effect of experimental diabetes on phenobarbital concentrations in rats at onset of loss of righting reflex

1 reference

12 December 2020

Pharmacokinetics, pharmacodynamics, and dose-response relationships of pancuronium in control and elderly subjects

1 reference

12 December 2020

Age-dependent dose-response relationship of ORG NC 45 in anaesthetized patients

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12 December 2020

Ventilatory depression during and after infusion of alfentanil in man.

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12 December 2020

Relaxant resistance in disuse atrophy: pharmacokinetics vs. pharmacodynamics.

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12 December 2020

Effects of clonidine on narcotic requirements and hemodynamic response during induction of fentanyl anesthesia and endotracheal intubation.

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12 December 2020

Dose–Response and Plasma Concentration–Response Relationships of Pancuronium in Man

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12 December 2020

Electro-encephalographic patterns produced by thiopental sodium during surgical operations; description and classification.

1 reference

12 December 2020

[Pharmacokinetics of etomidate in man (author's transl)]

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12 December 2020

The effect of cirrhosis on the disposition and elimination of meperidine in man

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12 December 2020

A model for studying depth of anesthesia and acute tolerance to thiopental.

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12 December 2020

Time-dependent increase in sensitivity to d-tubocurarine during enflurane anesthesia in man.

1 reference

12 December 2020

The Pharmacokinetics of Alfentanil (R39209): A New Opioid Analgesic

1 reference

12 December 2020

The pharmacokinetics and pharmacodynamics of atracurium in patients with and without renal failure

1 reference

12 December 2020

Plasma levels of thiopental necessary for anesthesia

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12 December 2020

Dose-independent pharmacokinetics of fentanyl.

1 reference

12 December 2020

Kinetics of drug action in disease states. V. Acute effect of urea infusion on phenobarbital concentrations in rats at onset of loss of righting reflex

1 reference

12 December 2020

Pharmacokinetics of etomidate, a new intravenous anesthetic

1 reference

12 December 2020

Quantitation of the EEG and pharmacodynamic modelling of hypnotic drugs: etomidate as an example

1 reference

12 December 2020

Kinetics of drug action in disease states. II. Effect of experimental renal dysfunction on phenobarbital concentrations in rats at onset of loss of righting reflect

1 reference

12 December 2020

Ketamine--its pharmacology and therapeutic uses.

1 reference

12 December 2020

Another look at acute tolerance to thiopentone.

1 reference

12 December 2020

The pharmacokinetics of thiopental in pediatric surgical patients.

1 reference

12 December 2020

Pharmacokinetic and pharmacodynamic modelling of propofol ('Diprivan') in volunteers and surgical patients

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12 December 2020

Pharmacokinetics of etomidate in surgical patients

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12 December 2020

Etomidate in urological outpatient anaesthesia. A clinical evaluation.

1 reference

12 December 2020

Pancuronium pharmacokinetics in patients with liver cirrhosis

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12 December 2020

Pharmacokinetics of etomidate associated with prolonged i.v. infusion

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12 December 2020

Diazepam effects and kinetics in Caucasians and Orientals

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12 December 2020

Postoperative analgesia

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12 December 2020

Alfentanil-oxygen anaesthesia for coronary artery surgery.

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12 December 2020

The anesthetic potency of fentanyl in terms of its reduction of enflurane MAC.

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12 December 2020

Minimum Alveolar Anesthetic Concentration

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12 December 2020

Alfentanil as an anesthetic induction agent--a comparison with thiopental-lidocaine.

1 reference

12 December 2020

Clinical pharmacokinetics of fentanyl and its newer derivatives.

1 reference

12 December 2020

Alfentanil-oxygen anaesthesia: plasma concentrations and clinical effects during variable-rate continuous infusion for coronary artery surgery.

1 reference

12 December 2020

A comparison of alphaprodine and meperidine pharmacokinetics

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12 December 2020

Plasma concentrations of alfentanil required to supplement nitrous oxide anaesthesia for lower abdominal surgery.

1 reference

12 December 2020

Pharmacokinetics and Pharmacodynamics of Vecuronium (ORG NC45) and Pancuronium in Anesthetized Humans

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12 December 2020

Thiopentone pharmacokinetics in patients with chronic alcoholism.

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12 December 2020

Dose-response relationships for infusions of Althesin or methohexitone.

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12 December 2020

Adrenocortical function following multiple anesthesia inductions with etomidate.

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12 December 2020

[Infusion model for etomidate (author's transl)]

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12 December 2020

Cardiorespiratory changes following induction of anaesthesia with etomidate in patients with cardiac disease

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12 December 2020

Pharmacokinetics and pharmacodynamics of thiopentone, A comparison between young and elderly patients.

1 reference

12 December 2020

Biodisposition of ketamine in the rat: self-induction of metabolism

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12 December 2020

Effects of High-dose Fentanyl Anesthesia on the Electroencephalogram

1 reference

12 December 2020

Infusion strategies to investigate the pharmacokinetics and pharmacodynamics of hypnotic drugs: etomidate as an example.

1 reference

12 December 2020

Characteristics of Succinylcholine Neuromuscular Blockade in Neonates

1 reference

12 December 2020

Intravenous Benzodiazepines as Anaesthetic Agents: Pharmacokinetics and Clinical Consequences

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12 December 2020

Intravenous fentanyl kinetics.

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12 December 2020

Binding of thiopental to plasma proteins: effects on distribution in the brain and heart

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12 December 2020

The effect of increasing age on thiopental disposition and anesthetic requirement

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12 December 2020

Relationship between blood meperidine concentrations and analgesic response: a preliminary report.

1 reference

12 December 2020

A pharmacokinetically designed etomidate infusion regimen for hypnosis.

1 reference

12 December 2020

Pharmacokinetics of intravenous morphine in patients anesthetized with enflurane-nitrous oxide.

1 reference

12 December 2020

Fazadinium and pancuronium: a pharmacodynamic study

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12 December 2020

Effect of azotemia upon the action of intravenous barbiturate anesthesia.

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12 December 2020

Plasma protein binding and distribution of fentanyl, sufentanil, alfentanil and lofentanil in blood

1 reference

12 December 2020

Clinical evaluation of atracurium besylate requirement for a stable muscle relaxation during surgery: lack of age-related effects.

1 reference

12 December 2020

Acute tolerance to thiopental.

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of d-tubocurarine and metocurine in the elderly

1 reference

12 December 2020

Kinetics of distribution of radioactive labeled muscle relaxants. 3. Investigations with 14C-succinyldicholine and 14C-succinylmonocholine during controlled conditions

1 reference

12 December 2020

The influence of body weight, sex and age on the dosage of thiopentone

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12 December 2020

On the cerebral accumulation of ketamine and the relationship between metabolism of the drug and its pharmacological effects

1 reference

12 December 2020

The decrease of the minimum alveolar anesthetic concentration produced by sufentanil in rats

1 reference

12 December 2020

Pharmacodynamics and Pharmacokinetics of Metocurine in Humans: Comparison to d-Tubocurarine

1 reference

12 December 2020

Determination and Applications of MAC

1 reference

12 December 2020

Patient-controlled analgesic therapy, Part IV: pharmacokinetics and analgesic plasma concentrations of morphine.

1 reference

12 December 2020

The neuromuscular effects of pancuronium in burned children

1 reference

12 December 2020

Pharmacokinetics of alfentanil in man

1 reference

12 December 2020

Alfentanil pharmacokinetics in patients with cirrhosis.

1 reference

12 December 2020

Clinical Pharmacokinetics Pethidine

1 reference

12 December 2020

Pharmacokinetics of methohexital and thiopental in surgical patients.

1 reference

12 December 2020

Kinetics of intravenous and intramuscular morphine

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12 December 2020

The relative potencies of methohexitone and thiopentone. A statistical study in man.

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12 December 2020

Minimum alveolar anesthetic concentration: a standard of anesthetic potency

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12 December 2020

10.2165/00003088-198712020-00001

Identifiers

DOI

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Dimensions Publication ID

14 September 2017

1022915105

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