(Q39766387)

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Paradoxical effects of a synthetic metalloproteinase inhibitor that blocks both p55 and p75 TNF receptor shedding and TNF alpha processing in RA synovial membrane cell cultures

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Paradoxical effects of a synthetic metalloproteinase inhibitor that blocks both p55 and p75 TNF receptor shedding and TNF alpha processing in RA synovial membrane cell cultures (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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author name string

Williams LM

1

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Gibbons DL

2

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Gearing A

3

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Maini RN

4

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Feldmann M

5

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Brennan FM

6

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

language of work or name

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publication date

1 June 1996

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

97

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

12

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

2833-2841

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

The human interferon alpha/beta receptor: characterization and molecular cloning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

22 September 2017

A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

22 September 2017

Soluble cytokine receptors are present in normal human urine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

22 September 2017

Ligand and protein kinase C downmodulate the colony-stimulating factor 1 receptor by independent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

22 September 2017

Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

22 September 2017

Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

22 September 2017

A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

22 September 2017

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

22 September 2017

Constitutive activity of the tumor necrosis factor promoter is canceled by the 3' untranslated region in nonmacrophage cell lines; a trans-dominant factor overcomes this suppressive effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

22 September 2017

TNF alpha--a pivotal role in rheumatoid arthritis?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

22 September 2017

Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

22 September 2017

Localization of tumor necrosis factor receptors in the synovial tissue and cartilage-pannus junction in patients with rheumatoid arthritis. Implications for local actions of tumor necrosis factor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

25 September 2017

Enhanced expression of tumor necrosis factor receptor mRNA and protein in mononuclear cells isolated from rheumatoid arthritis synovial joints

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

25 September 2017

Regulation of tumour necrosis factor-alpha processing by a metalloproteinase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

25 September 2017

Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

25 September 2017

TNF receptor fusion proteins are effective inhibitors of TNF-mediated cytotoxicity on human KYM-1D4 rhabdomyosarcoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

25 September 2017

Mechanism of release of soluble forms of tumor necrosis factor/lymphotoxin receptors by phorbol myristate acetate-stimulated human THP-1 cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

15 June 2018

Differential regulation of tumour necrosis factor receptors (TNF-R) by IL-4; upregulation of P55 and P75 TNF-R on synovial joint mononuclear cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

15 June 2018

TNF inhibitors are produced spontaneously by rheumatoid and osteoarthritic synovial joint cell cultures: evidence of feedback control of TNF action.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

15 June 2018

Inhibition of cartilage and bone destruction in adjuvant arthritis in the rat by a matrix metalloproteinase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

15 June 2018

The murine interleukin-4 receptor: molecular cloning and characterization of secreted and membrane bound forms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

15 June 2018

Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

15 June 2018

The activation of human type IV collagenase proenzyme. Sequence identification of the major conversion product following organomercurial activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

15 June 2018

Shedding of tumor necrosis factor receptors by activated human neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

15 June 2018

A cytotoxicity assay for tumour necrosis factor using a human rhabdomyosarcoma cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

15 June 2018

Evaluation of measurement of human TNF in plasma by ELISA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

15 June 2018

Purification and characterization of a novel soluble receptor for interleukin 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

15 June 2018

Human neutrophil elastase releases a ligand-binding fragment from the 75-kDa tumor necrosis factor (TNF) receptor. Comparison with the proteolytic activity responsible for shedding of TNF receptors from stimulated neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

15 June 2018

Soluble interleukin 2 receptors are released from activated human lymphoid cells in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

3 July 2018

Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti TNF-alpha antibody with the interleukin-1 receptor antagonist.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

20 August 2018

Immunoregulatory role of interleukin 10 in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

20 August 2018

Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

20 August 2018

A tumor necrosis factor-binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507377

20 August 2018

Slow release of soluble TNF receptors by monocytes in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/8675695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of tumour necrosis factor-α precursor by metalloproteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/8675695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and biologic characterization of a specific tumor necrosis factor alpha inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8675695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infusion of tumor necrosis factor (TNF) causes an increase in circulating TNF-binding protein in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/8675695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: regulation by tumor necrosis factor-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/8675695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Joint destruction in arthritis: metalloproteinases in the spotlight

1 reference

https://pubmed.ncbi.nlm.nih.gov/8675695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of tumor necrosis factor alpha in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8675695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/8675695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/8675695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of an Asn/Val cleavage site in the production of a soluble form of a human tumor necrosis factor (TNF) receptor. Site-directed mutagenesis of a putative cleavage site in the p55 TNF receptor chain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8675695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two inhibitors of pro-inflammatory cytokine release, interleukin-10 and interleukin-4, have contrasting effects on release of soluble p75 tumor necrosis factor receptor by cultured monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8675695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical antiarthritic activity of matrix metalloproteinase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/8675695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinases degrade myelin basic protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/8675695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of a metalloprotease in low-affinity nerve growth factor receptor truncation: inhibition of truncation in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/8675695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of tumor necrosis factor receptors on human monocytes and internalization of receptor bound ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/8675695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI118739

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

ResearchGate publication ID

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