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Therapeutic implications of new insights into the critical role of VP16 in initiating the earliest stages of HSV reactivation from latency.
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Europe PubMed Central
PMC publication ID
3087177
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426158%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
title
Therapeutic implications of new insights into the critical role of VP16 in initiating the earliest stages of HSV reactivation from latency
(English)
1 reference
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Europe PubMed Central
PMC publication ID
3087177
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426158%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
author
Richard L. Thompson
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
3087177
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426158%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
author name string
Nancy M Sawtell
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2
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Europe PubMed Central
PMC publication ID
3087177
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426158%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
publication date
1 July 2010
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Europe PubMed Central
PMC publication ID
3087177
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426158%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
published in
Future Medicinal Chemistry
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stated in
Europe PubMed Central
PMC publication ID
3087177
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426158%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
volume
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3087177
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426158%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
issue
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
3087177
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426158%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
page(s)
1099-1105
1 reference
stated in
Europe PubMed Central
PMC publication ID
3087177
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426158%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
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Evidence that the herpes simplex virus type 1 ICP0 protein does not initiate reactivation from latency in vivo
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Herpes simplex virus DNA synthesis is not a decisive regulatory event in the initiation of lytic viral protein expression in neurons in vivo during primary infection or reactivation from latency
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Reversal of the silencing of tetracycline-controlled genes requires the coordinate action of distinctly acting transcription factors
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Analysis of Herpes Simplex Virus ICP0 Promoter Function in Sensory Neurons during Acute Infection, Establishment of Latency, and Reactivation In Vivo
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The herpes simplex virus VP16-induced complex: the makings of a regulatory switch
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Quantitative analysis of herpes simplex virus reactivation in vivo demonstrates that reactivation in the nervous system is not inhibited at early times postinoculation
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22 September 2017
Cytokines in experimental herpes simplex virus infection
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22 September 2017
Samarangenin B from Limonium sinense suppresses herpes simplex virus type 1 replication in Vero cells by regulation of viral macromolecular synthesis
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Herpes simplex virus type 1 latency-associated transcript gene promotes neuronal survival
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22 September 2017
ICP0 is required for efficient reactivation of herpes simplex virus type 1 from neuronal latency
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22 September 2017
The probability of in vivo reactivation of herpes simplex virus type 1 increases with the number of latently infected neurons in the ganglia
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22 September 2017
Interdigitated residues within a small region of VP16 interact with Oct-1, HCF, and DNA
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22 September 2017
Comprehensive quantification of herpes simplex virus latency at the single-cell level
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22 September 2017
Evidence for a novel regulatory pathway for herpes simplex virus gene expression in trigeminal ganglion neurons.
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The herpes simplex virus type 1 regulatory protein ICP0 enhances virus replication during acute infection and reactivation from latency.
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22 September 2017
Host cell proteins bind to the cis-acting site required for virion-mediated induction of herpes simplex virus 1 alpha genes
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22 September 2017
A complex formed between cell components and an HSV structural polypeptide binds to a viral immediate early gene regulatory DNA sequence
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22 September 2017
Construction and characterization of a herpes simplex virus type 1 mutant unable to transinduce immediate-early gene expression
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22 September 2017
During latency, herpes simplex virus type 1 DNA is associated with nucleosomes in a chromatin structure
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22 September 2017
Quantitative polymerase chain reaction analysis of herpes simplex virus DNA in ganglia of mice infected with replication-incompetent mutants
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22 September 2017
A herpes simplex virus type 1 mutant containing a nontransinducing Vmw65 protein establishes latent infection in vivo in the absence of viral replication and reactivates efficiently from explanted trigeminal ganglia
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22 September 2017
Interference with the assembly of a virus-host transcription complex by peptide competition
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22 September 2017
Expression of the herpes simplex virus 1 alpha transinducing factor (VP16) does not induce reactivation of latent virus or prevent the establishment of latency in mice
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22 September 2017
Herpes simplex virus type 1 mutant strain in1814 establishes a unique, slowly progressing infection in SCID mice
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22 September 2017
Herpes simplex virus type 1 latency-associated transcription unit promotes anatomical site-dependent establishment and reactivation from latency
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22 September 2017
Rapid in vivo reactivation of herpes simplex virus in latently infected murine ganglionic neurons after transient hyperthermia
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22 September 2017
Comparison of herpes simplex virus reactivation in ganglia in vivo and in explants demonstrates quantitative and qualitative differences
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25 September 2017
Evidence of DNA: protein interactions that mediate HSV-1 immediate early gene activation by VP16.
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25 September 2017
The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16.
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15 June 2018
Herpes simplex virus neurovirulence and productive infection of neural cells is associated with a function which maps between 0.82 and 0.832 map units on the HSV genome
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15 June 2018
Noncytotoxic lytic granule-mediated CD8+ T cell inhibition of HSV-1 reactivation from neuronal latency
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20 August 2018
Latency of alpha-herpes viruses is accompanied by a chronic inflammation in human trigeminal ganglia but not in dorsal root ganglia.
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20 August 2018
Yatein from Chamaecyparis obtusa suppresses herpes simplex virus type 1 replication in HeLa cells by interruption the immediate-early gene expression
1 reference
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20 August 2018
Anti-herpes simplex virus type-1 flavonoids and a new flavanone from the root of Limonium sinense
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087177
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20 August 2018
Reactivation in vivo and in vitro of herpes simplex virus from mouse dorsal root ganglia which contain different levels of latency-associated transcripts
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087177
retrieved
20 August 2018
RNA complementary to a herpesvirus alpha gene mRNA is prominent in latently infected neurons
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21426158
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Drug-induced crystal nephropathy: an update
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21426158
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.4155/FMC.10.197
1 reference
stated in
Europe PubMed Central
PMC publication ID
3087177
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426158%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
PMC publication ID
3087177
1 reference
stated in
Europe PubMed Central
PMC publication ID
3087177
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426158%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
PubMed publication ID
21426158
1 reference
stated in
Europe PubMed Central
PMC publication ID
3087177
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426158%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
ResearchGate publication ID
50807247
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