(Q39780609)

14 September 2017

LIM-kinase 2, a regulator of actin dynamics, is involved in mitotic spindle integrity and sensitivity to microtubule-destabilizing drugs (English)

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14 September 2017

S T Po'uha

1

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14 September 2017

M S Y Shum

2

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14 September 2017

A Goebel

3

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14 September 2017

O Bernard

4

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14 September 2017

M Kavallaris

5

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14 September 2017

language of work or name

English

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publication date

2 November 2009

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14 September 2017

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14 September 2017

29

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14 September 2017

597-607

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14 September 2017

4

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https://scigraph.springernature.com/pub.10.1038/onc.2009.367

14 September 2017

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cites work

The phosphorylation of p25/TPPP by LIM kinase 1 inhibits its ability to assemble microtubules

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

LIM kinase 2 is widely expressed in all tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Microtubule-targeted anticancer agents and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Phosphorylated LIM kinases colocalize with gamma-tubulin in centrosomes during early stages of mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

The Rho GTPase effector ROCK regulates cyclin A, cyclin D1, and p27Kip1 levels by distinct mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Cytoskeletal changes regulated by the PAK4 serine/threonine kinase are mediated by LIM kinase 1 and cofilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Expression of LIM kinase 1 is associated with reversible G1/S phase arrest, chromosomal instability and prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Microtubule-destabilizing agents induce focal adhesion structure disorganization and anoikis in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility through slingshot

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

LIM kinase 1 coordinates microtubule stability and actin polymerization in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Vincristine induces dramatic lysosomal changes and sensitizes cancer cells to lysosome-destabilizing siramesine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

LIM kinase-mediated cofilin phosphorylation during mitosis is required for precise spindle positioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

MAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Multidrug resistance in human neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Identification and characterization of a novel family of serine/threonine kinases containing two N-terminal LIM motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Protein kinase D regulates cell migration by direct phosphorylation of the cofilin phosphatase slingshot 1 like

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Regulation of the neuronal actin cytoskeleton by ADF/cofilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Different activity regulation and subcellular localization of LIMK1 and LIMK2 during cell cycle transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Microtubule alterations and mutations induced by desoxyepothilone B: implications for drug-target interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Improving the targeting of tubulin-binding agents: lessons from drug resistance studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Proteomic analysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukemia--an in vivo study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

The serine phosphatases PP1 and PP2A associate with and activate the actin-binding protein cofilin in human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Cell cycle effects and induction of premitotic apoptosis by irofulven in synchronized cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

Alterations in gamma-actin and tubulin-targeted drug resistance in childhood leukemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.367

31 March 2020

Identifiers

DOI

10.1038/ONC.2009.367

1 reference

14 September 2017

1 reference