(Q39783049)

English

Truncation of alphaB-crystallin by the myopathy-causing Q151X mutation significantly destabilizes the protein leading to aggregate formation in transfected cells

scientific article published on 29 January 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Truncation of alphaB-crystallin by the myopathy-causing Q151X mutation significantly destabilizes the protein leading to aggregate formation in transfected cells (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

author name string

Victoria H Hayes

1

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Glyn Devlin

2

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Roy A Quinlan

3

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

language of work or name

0 references

publication date

29 January 2008

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

283

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

16

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

10500-10512

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Interactive sequences in the molecular chaperone, human alphaB crystallin modulate the fibrillation of amyloidogenic proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Site-directed mutations in the C-terminal extension of human alphaB-crystallin affect chaperone function and block amyloid fibril formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Primary desminopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

A novel alphaB-crystallin mutation associated with autosomal dominant congenital lamellar cataract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Desmin aggregate formation by R120G alphaB-crystallin is caused by altered filament interactions and is dependent upon network status in cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Influence of the C-Terminal Residues on Oligomerization of αA-Crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

On the mechanism of chaperone activity of the small heat-shock protein of Methanococcus jannaschii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

The nonhelical tail domain of keratin 14 promotes filament bundling and enhances the mechanical properties of keratin intermediate filaments in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Crystal structure and assembly of a eukaryotic small heat shock protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Alpha-B crystallin gene (CRYAB) mutation causes dominant congenital posterior polar cataract in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Characterization of two novel human small heat shock proteins: protein kinase-related HspB8 and testis-specific HspB9.

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

https://api.crossref.org/works/10.1074%2FJBC.M706453200

21 January 2018

A novel quaternary structure of the dimeric alpha-crystallin domain with chaperone-like activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Tracking pathology with proteomics: identification of in vivo degradation products of alphaB-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

The cardiomyopathy and lens cataract mutation in alphaB-crystallin alters its protein structure, chaperone activity, and interaction with intermediate filaments in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Mutation R120G in alphaB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

A dysfunctional desmin mutation in a patient with severe generalized myopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Crystal structure of a small heat-shock protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Missense mutations in desmin associated with familial cardiac and skeletal myopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Small heat shock protein of Methanococcus jannaschii, a hyperthermophile

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Cloning, expression, and chaperone-like activity of human alphaA-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Alpha B-crystallin is a small heat shock protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Immunoreactive alpha A crystallin in rat non-lenticular tissues detected with a sensitive immunoassay method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Lens proteins and their genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Alpha-crystallin can function as a molecular chaperone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

22 September 2017

Intermediate filament interactions can be altered by HSP27 and alphaB-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

25 September 2017

Chaperone activity of alpha-crystallins modulates intermediate filament assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

25 September 2017

Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

17 June 2018

Insights into the domains required for dimerization and assembly of human alphaB crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

17 June 2018

Small heat-shock protein structures reveal a continuum from symmetric to variable assemblies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

17 June 2018

Genealogy of the alpha-crystallin--small heat-shock protein superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

17 June 2018

Effects of site-directed mutations on the chaperone-like activity of alphaB-crystallin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

17 June 2018

Expression in Escherichia coli of fragments of glial fibrillary acidic protein: characterization, assembly properties and paracrystal formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

17 June 2018

Tissue distribution and developmental profiles of immunoreactive alpha B crystallin in the rat determined with a sensitive immunoassay system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

17 June 2018

Expression of alpha B-crystallin in the developing rat kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

17 June 2018

Heat shock protein 27 and alpha B-crystallin can form a complex, which dissociates by heat shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

17 June 2018

Intracellular degradation and deamidation of alpha-crystallin subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

17 June 2018

Alpha B-crystallin mutation in dilated cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

20 August 2018

Interactive domains for chaperone activity in the small heat shock protein, human alphaB crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

20 August 2018

Dodecameric structure of the small heat shock protein Acr1 from Mycobacterium tuberculosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

20 August 2018

The native oligomeric organization of alpha-crystallin, is it necessary for its chaperone function?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

20 August 2018

The IXI/V motif in the C-terminal extension of alpha-crystallins: alternative interactions and oligomeric assemblies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

20 August 2018

Phosphorylation of alphaB-crystallin alters chaperone function through loss of dimeric substructure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

20 August 2018

Myofibrillar myopathy caused by novel dominant negative alpha B-crystallin mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

20 August 2018

Role of the conserved SRLFDQFFG region of alpha-crystallin, a small heat shock protein. Effect on oligomeric size, subunit exchange, and chaperone-like activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

20 August 2018

Lens alpha-crystallin: chaperone-like properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

20 August 2018

The small heat-shock protein, alphaB-crystallin, has a variable quaternary structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2447664

20 August 2018

Characterisation of amyloid fibril formation by small heat-shock chaperone proteins human alphaA-, alphaB- and R120G alphaB-crystallins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706453200

21 January 2018

Mass measurements of C-terminally truncated alpha-crystallins from two-dimensional gels identify Lp82 as a major endopeptidase in rat lens

1 reference

https://pubmed.ncbi.nlm.nih.gov/18230612

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced C-terminal truncation of alphaA- and alphaB-crystallins in diabetic lenses

1 reference

https://pubmed.ncbi.nlm.nih.gov/18230612

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione adducts, not carbamylated lysines, are the major modification of lens alpha-crystallins from renal failure patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18230612

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies of the denaturation patterns of bovine alpha-crystallin using an ionic denaturant, guanidine hydrochloride and a non-ionic denaturant, urea

1 reference

https://pubmed.ncbi.nlm.nih.gov/18230612

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wrapping the alpha-crystallin domain fold in a chaperone assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/18230612

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interaction between alphaA- and alphaB-crystallin is sequence-specific

1 reference

https://pubmed.ncbi.nlm.nih.gov/18230612

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-based analysis of the beta8 interactive sequence of human alphaB crystallin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18230612

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of arginine-163 and the 163REEK166 motif in the oligomerization of truncated alpha A-crystallins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18230612

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myopathy-associated alphaB-crystallin mutants: abnormal phosphorylation, intracellular location, and interactions with other small heat shock proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18230612

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An atypical form of alphaB-crystallin is present in high concentration in some human cataractous lenses. Identification and characterization of aberrant N- and C-terminal processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/18230612

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lens proteomics: the accumulation of crystallin modifications in the mouse lens with age

1 reference

https://pubmed.ncbi.nlm.nih.gov/18230612

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M706453200

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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