(Q39788993)

English

5-(Perylen-3-yl)ethynyl-arabino-uridine (aUY11), an arabino-based rigid amphipathic fusion inhibitor, targets virion envelope lipids to inhibit fusion of influenza virus, hepatitis C virus, and other enveloped viruses

scientific article published on 2 January 2013

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scholarly article

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21 February 2020

5-(Perylen-3-yl)ethynyl-arabino-uridine (aUY11), an arabino-based rigid amphipathic fusion inhibitor, targets virion envelope lipids to inhibit fusion of influenza virus, hepatitis C virus, and other enveloped viruses (English)

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21 February 2020

Hepatitis C virus

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based on heuristic

inferred from title

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based on heuristic

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1

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21 February 2020

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21 February 2020

Richard M. Epand

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Raquel F Epand

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21 February 2020

Richard M Epand

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21 February 2020

Vladimir A Korshun

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21 February 2020

Luis M Schang

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21 February 2020

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2 January 2013

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21 February 2020

Journal of Virology

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21 February 2020

87

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21 February 2020

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21 February 2020

3640-3654

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21 February 2020

describes a project that uses

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11 June 2022

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PD 404,182 is a virocidal small molecule that disrupts hepatitis C virus and human immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Mechanism of inhibition of enveloped virus membrane fusion by the antiviral drug arbidol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Targeting cell entry of enveloped viruses as an antiviral strategy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Rigid amphipathic fusion inhibitors, small molecule antiviral compounds against enveloped viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Respiratory syncytial virus-neutralizing monoclonal antibodies motavizumab and palivizumab inhibit fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Peptide Inhibitors of Dengue-Virus Entry Target a Late-Stage Fusion Intermediate

1 reference

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22 September 2017

The Disulfide Bonds in Glycoprotein E2 of Hepatitis C Virus Reveal the Tertiary Organization of the Molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

A peptide derived from hepatitis C virus E2 envelope protein inhibits a post-binding step in HCV entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

A broad-spectrum antiviral targeting entry of enveloped viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Synthetic therapeutic peptides: science and market

1 reference

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22 September 2017

Characteristics of arbidol-resistant mutants of influenza virus: implications for the mechanism of anti-influenza action of arbidol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Viral membrane fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Arbidol: a broad-spectrum antiviral compound that blocks viral fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Hepatitis C virus NS5A anchor peptide disrupts human immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

A virocidal amphipathic -helical peptide that inhibits hepatitis C virus infection in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Lipids as modulators of membrane fusion mediated by viral fusion proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Design of helical, oligomeric HIV-1 fusion inhibitor peptides with potent activity against enfuvirtide-resistant virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Biochemical mechanism of hepatitis C virus inhibition by the broad-spectrum antiviral arbidol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Structure of the prefusion form of the vesicular stomatitis virus glycoprotein G

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Class II virus membrane fusion proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Viral strategies for evading antiviral cellular immune responses of the host

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

The broad anti-viral agent glycyrrhizin directly modulates the fluidity of plasma membrane and HIV-1 envelope

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

The many mechanisms of viral membrane fusion proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Protein-Lipid Interplay in Fusion and Fission of Biological Membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Rabies virus-induced membrane fusion pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Structural intermediates in influenza haemagglutinin-mediated fusion

1 reference

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22 September 2017

Structure of the hemagglutinin precursor cleavage site, a determinant of influenza pathogenicity and the origin of the labile conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

An early stage of membrane fusion mediated by the low pH conformation of influenza hemagglutinin depends upon membrane lipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Inhibition of membrane fusion by lysophosphatidylcholine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Peripheral blood mononuclear phagocytes mediate dissemination of murine cytomegalovirus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Structure of influenza haemagglutinin at the pH of membrane fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection

1 reference

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22 September 2017

The relationship between membrane fluidity and permeabilities to water, solutes, ammonia, and protons

1 reference

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22 September 2017

Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Infectious cell entry mechanism of influenza virus.

1 reference

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22 September 2017

pH-sensitive liposomes: acid-induced liposome fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

The structure and function of the hemagglutinin membrane glycoprotein of influenza virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Reversible conformational changes and fusion activity of rabies virus glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Fluidity parameters of lipid regions determined by fluorescence polarization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624206

22 September 2017

Non-bilayer lipids and biological fusion intermediates

1 reference

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25 September 2017

Effect of membrane curvature-modifying lipids on membrane fusion by tick-borne encephalitis virus

1 reference

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25 September 2017

During lytic infections, herpes simplex virus type 1 DNA is in complexes with the properties of unstable nucleosomes

1 reference

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15 June 2018

Lysophosphatidylcholine reversibly arrests exocytosis and viral fusion at a stage between triggering and membrane merger.

1 reference

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15 June 2018

Virus replication inhibitory peptide inhibits the conversion of phospholipid bilayers to the hexagonal phase.

1 reference

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15 June 2018

Penetration of cells by herpes simplex virus does not require a low pH-dependent endocytic pathway

1 reference

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15 June 2018

Membranotropic effects of arbidol, a broad anti-viral molecule, on phospholipid model membranes

1 reference

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Isolation and characterization of human immunodeficiency virus type 1 resistant to the small-molecule CCR5 antagonist TAK-652.

1 reference

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20 August 2018

5-Arylethynyl-2'-deoxyuridines, compounds active against HSV-1.

1 reference

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20 August 2018

Influence of membrane fluidity on human immunodeficiency virus type 1 entry

1 reference

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Antiviral activity of some 5-arylethynyl 2'-deoxyuridine derivatives

1 reference

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20 August 2018

Inhibition of influenza-induced membrane fusion by lysophosphatidylcholine

1 reference

https://pubmed.ncbi.nlm.nih.gov/23283943

12 December 2020

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10.1128/JVI.02882-12

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23283943%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PMC publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23283943%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PubMed publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23283943%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

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