(Q39789538)

14 September 2017

title

Inhibitory effect of cucurbitacin E on pancreatic cancer cells growth via STAT3 signaling (English)

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14 September 2017

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ChEBI release 2020-05-28

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Chunyan Sun

1

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14 September 2017

Meixia Zhang

2

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14 September 2017

Xiaolei Shan

3

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14 September 2017

Xueying Zhou

4

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14 September 2017

Jiao Yang

5

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14 September 2017

Yanli Wang

6

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14 September 2017

Jesse Li-Ling

7

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14 September 2017

Yihui Deng

8

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14 September 2017

publication date

9 October 2009

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Journal of Cancer Research and Clinical Oncology

14 September 2017

published in

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14 September 2017

volume

136

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14 September 2017

issue

4

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14 September 2017

page(s)

603-610

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https://scigraph.springernature.com/pub.10.1007/s00432-009-0698-x

14 September 2017

exact match

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cites work

Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer.

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00432-009-0698-X

Adjuvant chemoradiotherapy for high-risk pancreatic cancer

21 January 2018

1 reference

12 December 2020

The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate

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12 December 2020

Growth inhibition of human hepatocellular carcinoma cells by blocking STAT3 activation with decoy-ODN.

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12 December 2020

Targeted constitutive activation of signal transducer and activator of transcription 3 in human hepatocellular carcinoma cells by cucurbitacin B.

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12 December 2020

Inhibitory effects of cucurbitacin B on laryngeal squamous cell carcinoma

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12 December 2020

Targeting the cytoplasmic and nuclear functions of signal transducers and activators of transcription 3 for cancer therapy

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12 December 2020

RNA interference-mediated signal transducers and activators of transcription 3 gene silencing inhibits invasion and metastasis of human pancreatic cancer cells

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12 December 2020

Role of Stat3 in regulating p53 expression and function

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12 December 2020

Bruceine D induces apoptosis in pancreatic adenocarcinoma cell line PANC-1 through the activation of p38-mitogen activated protein kinase.

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12 December 2020

STAT3 as a target for inducing apoptosis in solid and hematological tumors

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12 December 2020

Pharmacogenomics and pancreatic cancer treatment. Optimizing current therapy and individualizing future therapy

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12 December 2020

Cucurbitacin Q: a selective STAT3 activation inhibitor with potent antitumor activity

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12 December 2020

In vitro and in vivo activity of novel small-molecule inhibitors targeting the pleckstrin homology domain of protein kinase B/AKT.

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12 December 2020

Characterization of mutations and loss of heterozygosity of p53 and K-ras2 in pancreatic cancer cell lines by immobilized polymerase chain reaction

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12 December 2020

Cucurbitacin B has a potent antiproliferative effect on breast cancer cells in vitro and in vivo

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12 December 2020

Molecular-targeted therapies: lessons from years of clinical development

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12 December 2020

p53 tumour suppressor gene expression in pancreatic neuroendocrine tumour cells

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12 December 2020

Inhibition of STAT3 Tyr705 phosphorylation by Smad4 suppresses transforming growth factor beta-mediated invasion and metastasis in pancreatic cancer cells

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12 December 2020

Metastatic pancreatic cancer 2008: is the glass less empty?

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12 December 2020

Growth inhibitory activity of cucurbitacin glucosides isolated from Citrullus colocynthis on human breast cancer cells

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12 December 2020

Nuclear factor-kappaB p65/relA silencing induces apoptosis and increases gemcitabine effectiveness in a subset of pancreatic cancer cells

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12 December 2020

Human pancreatic carcinomas and cell lines reveal frequent and multiple alterations in the p53 and Rb-1 tumor-suppressor genes

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12 December 2020

p53 and K-RAS alterations in pancreatic epithelial cell lesions

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12 December 2020

Cucurbitacin B markedly inhibits growth and rapidly affects the cytoskeleton in glioblastoma multiforme.

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12 December 2020

Flavonoids, phenoxodiol, and a novel agent, triphendiol, for the treatment of pancreaticobiliary cancers

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12 December 2020

Cucurbitacin E targets proliferating endothelia

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12 December 2020

Direct interaction of Cucurbitacin E isolated from Alsomitra macrocarpa to actin filament

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12 December 2020

Phase II study of docetaxel and gefitinib as second-line therapy in gemcitabine pretreated patients with advanced pancreatic cancer

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12 December 2020

Phase II trial of S-1 in combination with gemcitabine for chemo-naïve patients with locally advanced or metastatic pancreatic cancer

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12 December 2020

STAT3 inhibition in prostate and pancreatic cancer lines by STAT3 binding sequence oligonucleotides: differential activity between 5' and 3' ends

1 reference

12 December 2020

Cetuximab plus gemcitabine/oxaliplatin (GEMOXCET) in first-line metastatic pancreatic cancer: a multicentre phase II study

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12 December 2020

Chmp 1A is a mediator of the anti-proliferative effects of all-trans retinoic acid in human pancreatic cancer cells

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12 December 2020

Anticancer and antiinflammatory activities of cucurbitacins from Cucurbita andreana

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12 December 2020

Signal transducers and activators of transcription 3 pathway activation in drug-resistant ovarian cancer

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12 December 2020

10.1007/S00432-009-0698-X

Identifiers

DOI

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14 September 2017

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