(Q39798451)

English

Activated human protein C prevents thrombin-induced thromboembolism in mice. Evidence that activated protein c reduces intravascular fibrin accumulation through the inhibition of additional thrombin generation

scientific article published on February 1998

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Activated human protein C prevents thrombin-induced thromboembolism in mice. Evidence that activated protein c reduces intravascular fibrin accumulation through the inhibition of additional thrombin generation (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

thromboembolism

1 reference

based on heuristic

inferred from title

drotrecogin alfa

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

author name string

Momi S

2

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Berrettini M

3

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Nenci GG

4

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Schwarz HP

5

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Semeraro N

6

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Colucci M

7

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

language of work or name

0 references

publication date

1 February 1998

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

101

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

3

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

667-676

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Thrombin-mediated activation of factor XI results in a thrombin-activatable fibrinolysis inhibitor-dependent inhibition of fibrinolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

22 September 2017

Replacement therapy with a monoclonal antibody purified protein C concentrate in newborns with severe congenital protein C deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

22 September 2017

TAFI, or plasma procarboxypeptidase B, couples the coagulation and fibrinolytic cascades through the thrombin-thrombomodulin complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

22 September 2017

Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

22 September 2017

Mutation in blood coagulation factor V associated with resistance to activated protein C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

22 September 2017

The antithrombotic effect of human activated protein C on He-Ne laser-induced thrombosis in rat mesenteric microvessels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

22 September 2017

Thrombin-induced endothelial cell dysfunction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

22 September 2017

Generation of fibrinolytic activity by infusion of activated protein C into dogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

22 September 2017

Influence of protein C activation on blood coagulation and fibrinolysis in squirrel monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

22 September 2017

Cross-linking of alpha 2-plasmin inhibitor to fibrin by fibrin-stabilizing factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

22 September 2017

Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

22 September 2017

Factor XI activation in a revised model of blood coagulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

22 September 2017

Initiation and regulation of tissue factor-dependent blood coagulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

22 September 2017

The protein C anticoagulant pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

22 September 2017

A rapid and sensitive 125I-fibrin solid-phase fibrinolytic assay for plasmin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

22 September 2017

Endothelial control of the cardiovascular system: recent advances

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

25 September 2017

Inhibition of platelet-dependent thrombus formation by human activated protein C in a primate model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

15 June 2018

Enhancement of tissue plasminogen activator-induced fibrinolysis by activated protein C in endotoxin-treated rabbits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

15 June 2018

Direct detection of activated protein C in blood from human subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

15 June 2018

Evidence suggestive of activation of the intrinsic pathway of blood coagulation after injection of factor Xa/phospholipid into rabbits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

20 August 2018

Bleeding time in rats: a comparison of different experimental conditions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508611

20 August 2018

On the mechanism of the antifibrinolytic activity of plasma carboxypeptidase B

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse antithrombotic assay: a simple method for the evaluation of antithrombotic agents in vivo. Potentiation of antithrombotic activity by ethyl alcohol

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of protein C-dependent clot lysis: role of plasminogen activator inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human protein C induces anticoagulation and increased fibrinolytic activity in the cat

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for thrombomodulin in the pathogenesis of thrombin-induced thromboembolism in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin infusion in endotoxin-treated rabbits reduces the plasma levels of plasminogen activator inhibitor: evidence for a protein-C-mediated mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of patients with disseminated intravascular coagulation by protein C

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antithrombotic effect of recombinant human thrombomodulin on thrombin-induced thromboembolism in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of protein C and activated protein C on coagulation and fibrinolysis in normal human subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The activated protein C-mediated enhancement of tissue-type plasminogen activator-induced fibrinolysis in a cell-free system

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Picotamide protects mice from death in a pulmonary embolism model by a mechanism independent from thromboxane suppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein C and fibrinolysis: a link between coagulation and fibrinolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation and coagulation: linked processes potentially regulated through a common pathway mediated by protein C

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alteration of fibrin network by activated protein C

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation and inactivation of human protein C by plasmin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibrinolytic activity in blood is distributed over a cellular and the plasma fraction which can be modulated separately

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Feedback activation of factor XI by thrombin in plasma results in additional formation of thrombin that protects fibrin clots from fibrinolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant human soluble thrombomodulin reduces endotoxin-induced pulmonary vascular injury via protein C activation in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoassay of murine t-PA, u-PA and PAI-1 using monoclonal antibodies raised in gene-inactivated mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The profibrinolytic effect of activated protein C in clots formed from plasma is TAFI-dependent

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inherited thrombophilia: Part 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9449701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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