(Q39799247)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19756449%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation (English)

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7 February 2020

4

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7 February 2020

Cinzia Rinaldo

6

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7 February 2020

Silvia Soddu

11

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7 February 2020

Marco G. Paggi

12

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7 February 2020

author name string

Rosario Amato

1

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7 February 2020

Lucia D'Antona

2

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7 February 2020

Giovanni Porciatti

3

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7 February 2020

Miranda Menniti

5

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7 February 2020

Nicola Costa

7

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7 February 2020

Emanuele Bellacchio

8

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7 February 2020

Stefano Mattarocci

9

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7 February 2020

Giorgio Fuiano

10

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7 February 2020

Florian Lang

13

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7 February 2020

Nicola Perrotti

14

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7 February 2020

publication date

11 September 2009

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Journal of Molecular Medicine

7 February 2020

published in

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7 February 2020

volume

87

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7 February 2020

issue

12

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7 February 2020

page(s)

1221-1239

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https://scigraph.springernature.com/pub.10.1007/s00109-009-0525-5

7 February 2020

exact match

0 references

cites work

p53 regulates myogenesis by triggering the differentiation activity of pRb.

1 reference

12 December 2020

Differential regulation of serum- and glucocorticoid-inducible kinase 1 (SGK1) splice variants based on alternative initiation of transcription

1 reference

12 December 2020

Cell cycle expression and p53 regulation of the cyclin-dependent kinase inhibitor p21.

1 reference

12 December 2020

Gene expression profile analysis in human hepatocellular carcinoma by cDNA microarray.

1 reference

12 December 2020

Adenovirus E1-transformed cells grow despite the continuous presence of transcriptionally active p53.

1 reference

12 December 2020

Deregulated expression of pro-survival and pro-apoptotic p53-dependent genes upon Elongator deficiency in colon cancer cells

1 reference

12 December 2020

Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation

1 reference

12 December 2020

Gene expression profiling in the midbrain of striatal 6-hydroxydopamine-injected mice

1 reference

12 December 2020

Phosphorylation of HDM2 by Akt.

1 reference

12 December 2020

p53 family members in myogenic differentiation and rhabdomyosarcoma development

1 reference

12 December 2020

Role of p53 in cell cycle regulation and apoptosis following exposure to proteasome inhibitors

1 reference

12 December 2020

mTOR-raptor binds and activates SGK1 to regulate p27 phosphorylation

1 reference

12 December 2020

Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum

1 reference

12 December 2020

RhoB facilitates c-Myc turnover by supporting efficient nuclear accumulation of GSK-3.

1 reference

12 December 2020

Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic.

1 reference

12 December 2020

Impaired renal Na(+) retention in the sgk1-knockout mouse

1 reference

12 December 2020

Conditional liver-specific expression of simian virus 40 T antigen leads to regulatable development of hepatic neoplasm in transgenic mice

1 reference

12 December 2020

Stabilization of p53 in human cytomegalovirus-initiated cells is associated with sequestration of HDM2 and decreased p53 ubiquitination

1 reference

12 December 2020

Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume

1 reference

12 December 2020

HDM2 phosphorylation by MAPKAP kinase 2.

1 reference

12 December 2020

The coordinate regulation of the p53 and mTOR pathways in cells

1 reference

12 December 2020

MDM2-regulated degradation of HIPK2 prevents p53Ser46 phosphorylation and DNA damage-induced apoptosis.

1 reference

12 December 2020

Activation of serum- and glucocorticoid-induced protein kinase (Sgk) by cyclic AMP and insulin

1 reference

12 December 2020

Epithelial Na+ channel stimulation by n-3 fatty acids requires proximity to a membrane-bound A-kinase-anchoring protein complexed with protein kinase A and phosphodiesterase.

1 reference

12 December 2020

p53 mutations in human cancers

1 reference

12 December 2020

p53 regulation by post-translational modification and nuclear retention in response to diverse stresses

1 reference

12 December 2020

The MDM2-p53 interaction.

1 reference

12 December 2020

p53-dependent inhibition of FKHRL1 in response to DNA damage through protein kinase SGK1

1 reference

12 December 2020

Activation of p53/p21/PUMA alliance and disruption of PI-3/Akt in multimodal targeting of apoptotic signaling cascades in cervical cancer cells by a pentacyclic triterpenediol from Boswellia serrata.

1 reference

12 December 2020

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

1 reference

12 December 2020

Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

1 reference

12 December 2020

The dual PI3 kinase/mTOR inhibitor PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in p53 wild-type AML.

1 reference

12 December 2020

Resistance of mice lacking the serum- and glucocorticoid-inducible kinase SGK1 against salt-sensitive hypertension induced by a high-fat diet

1 reference

12 December 2020

Regulation of the G2/M transition by p53.

1 reference

12 December 2020

Repression of glucocorticoid receptor transactivation and DNA binding of a glucocorticoid response element within the serum/glucocorticoid-inducible protein kinase (sgk) gene promoter by the p53 tumor suppressor protein

1 reference

12 December 2020

Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf

1 reference

12 December 2020

Membrane androgen receptor activation in prostate and breast tumor cells: molecular signaling and clinical impact

1 reference

12 December 2020

Serum- and glucocorticoid-regulated kinase (SGK1) gene and blood pressure

1 reference

12 December 2020

SGK1 survival through various lives may save us all.

1 reference

12 December 2020

IL-2 signals through Sgk1 and inhibits proliferation and apoptosis in kidney cancer cells

1 reference

12 December 2020

p53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding.

1 reference

12 December 2020

Mesothelin is not required for normal mouse development or reproduction

1 reference

12 December 2020

Experimental tests to definitively determine ubiquitylation of a substrate.

1 reference

12 December 2020

The MDM2 RING-finger domain is required to promote p53 nuclear export

1 reference

12 December 2020

sgk: an essential convergence point for peptide and steroid hormone regulation of ENaC-mediated Na+ transport

1 reference

12 December 2020

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

1 reference

12 December 2020

(Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms

1 reference

12 December 2020

Mono- versus polyubiquitination: differential control of p53 fate by Mdm2.

1 reference

12 December 2020

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

1 reference

12 December 2020

Genetic variance of SGK-1 is associated with blood pressure, blood pressure change over time and strength of the insulin-diastolic blood pressure relationship.

1 reference

12 December 2020

Stabilization and activation of p53 induced by Cdk5 contributes to neuronal cell death

1 reference

12 December 2020

Expression of the serum- and glucocorticoid-inducible protein kinase, Sgk, is a cell survival response to multiple types of environmental stress stimuli in mammary epithelial cells

1 reference

12 December 2020

Glucocorticoid receptor-mediated protection from apoptosis is associated with induction of the serine/threonine survival kinase gene, sgk-1.

1 reference

12 December 2020