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The SMN protein is a key regulator of nuclear architecture in differentiating neuroblastoma cells.
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stated in
Europe PubMed Central
PMCID
2788272
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19735367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
title
The SMN protein is a key regulator of nuclear architecture in differentiating neuroblastoma cells
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2788272
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19735367%20AND%20SRC:MED&resulttype=core&format=json
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7 February 2020
main subject
differentiating neuroblastoma
1 reference
based on heuristic
inferred from title
author
Judith E. Sleeman
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
2788272
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19735367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
author name string
Allyson K Clelland
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2788272
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19735367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
Nicholas P Kinnear
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2
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stated in
Europe PubMed Central
PMCID
2788272
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19735367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
Lisa Oram
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3
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PMCID
2788272
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19735367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
Julie Burza
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
2788272
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19735367%20AND%20SRC:MED&resulttype=core&format=json
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7 February 2020
publication date
4 August 2009
1 reference
stated in
Europe PubMed Central
PMCID
2788272
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19735367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
published in
Traffic
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Europe PubMed Central
PMCID
2788272
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19735367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
volume
10
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Europe PubMed Central
PMCID
2788272
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19735367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
issue
11
1 reference
stated in
Europe PubMed Central
PMCID
2788272
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19735367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
page(s)
1585-1598
1 reference
stated in
Europe PubMed Central
PMCID
2788272
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19735367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
cites work
SMN complex localizes to the sarcomeric Z-disc and is a proteolytic target of calpain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
SMN deficiency causes tissue-specific perturbations in the repertoire of snRNAs and widespread defects in splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
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22 September 2017
Spliceosomal small nuclear ribonucleoprotein particles repeatedly cycle through Cajal bodies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
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22 September 2017
Ribonucleoprotein assembly defects correlate with spinal muscular atrophy severity and preferentially affect a subset of spliceosomal snRNPs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Molecular functions of the SMN complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Two distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
A Drosophila melanogaster model of spinal muscular atrophy reveals a function for SMN in striated muscle.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
UV-induced fragmentation of Cajal bodies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Depletion of SMN by RNA interference in HeLa cells induces defects in Cajal body formation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Ongoing U snRNP biogenesis is required for the integrity of Cajal bodies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Pumping RNA: nuclear bodybuilding along the RNP pipeline.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
The Cajal body: a meeting place for spliceosomal snRNPs in the nuclear maze
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
The C-terminal domain of coilin interacts with Sm proteins and U snRNPs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Targeting SMN to Cajal bodies and nuclear gems during neuritogenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Smn, the spinal muscular atrophy-determining gene product, modulates axon growth and localization of beta-actin mRNA in growth cones of motoneurons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Modification of Sm small nuclear RNAs occurs in the nucleoplasmic Cajal body following import from the cytoplasm
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Cajal body proteins SMN and Coilin show differential dynamic behaviour in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Control of Cajal body number is mediated by the coilin C-terminus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Coilin methylation regulates nuclear body formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Cajal body-specific small nuclear RNAs: a novel class of 2'-O-methylation and pseudouridylation guide RNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
snRNP protein expression enhances the formation of Cajal bodies containing p80-coilin and SMN
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B' and the Sm-like protein LSm4, and their interaction with the SMN protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Residual Cajal bodies in coilin knockout mice fail to recruit Sm snRNPs and SMN, the spinal muscular atrophy gene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
SMN, the product of the spinal muscular atrophy gene, binds preferentially to dimethylarginine-containing protein targets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Nuclear gems and Cajal (coiled) bodies in fetal tissues: nucleolar distribution of the spinal muscular atrophy protein, SMN
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Self-association of coilin reveals a common theme in nuclear body localization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D1 and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
The spinal muscular atrophy disease gene product, SMN: A link between snRNP biogenesis and the Cajal (coiled) body
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Newly assembled snRNPs associate with coiled bodies before speckles, suggesting a nuclear snRNP maturation pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Structure and assembly of the spliceosomal small nuclear ribonucleoprotein particles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
A novel nuclear structure containing the survival of motor neurons protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Identification and characterization of a spinal muscular atrophy-determining gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Mutational analysis of p80 coilin indicates a functional interaction between coiled bodies and the nucleolus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
Differences in snRNP localization between transformed and nontransformed cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
22 September 2017
In vivo analysis of Cajal body movement, separation, and joining in live human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
25 September 2017
Sequential treatment of SH-SY5Y cells with retinoic acid and brain-derived neurotrophic factor gives rise to fully differentiated, neurotrophic factor-dependent, human neuron-like cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
25 September 2017
Reduced U snRNP assembly causes motor axon degeneration in an animal model for spinal muscular atrophy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
17 June 2018
Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
20 August 2018
Multiprotein complexes of the survival of motor neuron protein SMN with Gemins traffic to neuronal processes and growth cones of motor neurons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
20 August 2018
A proteomic analysis of arginine-methylated protein complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
20 August 2018
The Relationship between SMN, the Spinal Muscular Atrophy Protein, and Nuclear Coiled Bodies in Differentiated Tissues and Cultured Cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
2 December 2018
Dynamic Interactions Between Splicing snRNPs, Coiled Bodies and Nucleoli Revealed Using snRNP Protein Fusions to the Green Fluorescent Protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788272
retrieved
2 December 2018
A regulatory role for CRM1 in the multi-directional trafficking of splicing snRNPs in the mammalian nucleus
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19735367
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1111/J.1600-0854.2009.00972.X
1 reference
stated in
Europe PubMed Central
PMCID
2788272
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19735367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
PMCID
2788272
1 reference
stated in
Europe PubMed Central
PMCID
2788272
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19735367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
PubMed ID
19735367
1 reference
stated in
Europe PubMed Central
PMCID
2788272
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19735367%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
ResearchGate publication ID
26794373
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