(Q39802740)

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Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19734941%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19734941%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Aloysius J. Klingelhutz

6

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7 February 2020

Wiljan Hendriks

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7 February 2020

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A C Hoover

1

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7 February 2020

G L Strand

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7 February 2020

P N Nowicki

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7 February 2020

M E Anderson

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7 February 2020

P D Vermeer

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7 February 2020

A D Bossler

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7 February 2020

J V Pottala

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7 February 2020

J H Lee

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7 February 2020

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7 September 2009

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7 February 2020

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7 February 2020

28

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7 February 2020

45

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7 February 2020

3960-3970

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7 February 2020

https://scigraph.springernature.com/pub.10.1038/onc.2009.251

0 references

Expression of the putative tumor suppressor gene PTPN13/PTPL1 is an independent prognostic marker for overall survival in breast cancer.

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22 September 2017

Phase I pharmacokinetic and pharmacodynamic study of the oral, small-molecule mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) in patients with advanced cancers

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22 September 2017

PTPL1: a large phosphatase with a split personality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785129

22 September 2017

The PDZ binding motif of human papillomavirus type 16 E6 induces PTPN13 loss, which allows anchorage-independent growth and synergizes with ras for invasive growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785129

22 September 2017

Protein tyrosine phosphatase PTPN13 negatively regulates Her2/ErbB2 malignant signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785129

22 September 2017

The putative tumor suppressor gene PTPN13/PTPL1 induces apoptosis through insulin receptor substrate-1 dephosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785129

22 September 2017

The role of human papillomavirus 16 E6 in anchorage-independent and invasive growth of mouse tonsil epithelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785129

22 September 2017

The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis

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22 September 2017

Prognostic impact of HER-2/neu expression on squamous head and neck carcinomas.

1 reference

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22 September 2017

Regulation of signal transducer and activator of transcription signaling by the tyrosine phosphatase PTP-BL.

1 reference

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22 September 2017

Clinical experience of MEK inhibitors in cancer therapy

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22 September 2017

New therapies for hepatocellular carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785129

22 September 2017

Loss of transforming growth factor-beta type II receptor promotes metastatic head-and-neck squamous cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785129

22 September 2017

Genetic characterization of fas-associated phosphatase-1 as a putative tumor suppressor gene on chromosome 4q21.3 in hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785129

22 September 2017

Clinging to life: cell to matrix adhesion and cell survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785129

22 September 2017

Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785129

22 September 2017

Multicenter phase II study of the oral MEK inhibitor, CI-1040, in patients with advanced non-small-cell lung, breast, colon, and pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785129

22 September 2017

Pathogenesis of human papillomaviruses in differentiating epithelia

1 reference

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22 September 2017

Signalling mechanisms of anoikis

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22 September 2017

Mutational analysis of the tyrosine phosphatome in colorectal cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785129

22 September 2017

PDZ domains - common players in the cell signaling

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22 September 2017

E6/E7 proteins of HPV type 16 and ErbB-2 cooperate to induce neoplastic transformation of primary normal oral epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785129

22 September 2017

The protein tyrosine phosphatase PTP-Basophil/Basophil-like. Interacting proteins and molecular functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785129

22 September 2017

Molecular pathogenesis of head and neck squamous cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785129

22 September 2017

Targeting epidermal growth factor receptor in head and neck cancer

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22 September 2017

Rules for making human tumor cells

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22 September 2017

The Hallmarks of Cancer

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ras mutations and expression in head and neck squamous cell carcinomas

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15 June 2018

Negative prognostic impact of the coexpression of epidermal growth factor receptor and c-erbB-2 in locally advanced cervical cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785129

20 August 2018

Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers.

1 reference

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Growth factor receptors and related signalling pathways as targets for novel treatment strategies of hepatocellular cancer

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20 August 2018

Deletion of the PDZ motif of HPV16 E6 preventing immortalization and anchorage-independent growth in human tonsil epithelial cells

1 reference

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Epigenetic disruption of two proapoptotic genes MAPK10/JNK3 and PTPN13/FAP-1 in multiple lymphomas and carcinomas through hypermethylation of a common bidirectional promoter.

1 reference

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20 August 2018

Phase I and pharmacodynamic study of the oral MEK inhibitor CI-1040 in patients with advanced malignancies

1 reference

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Mild impairment of motor nerve repair in mice lacking PTP-BL tyrosine phosphatase activity

1 reference

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20 August 2018

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1 reference

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31 March 2020

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10.1038/ONC.2009.251

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7 February 2020

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7 February 2020

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7 February 2020

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