(Q39804025)

14 September 2017

High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer (English)

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14 September 2017

Runqiu Jiang

1

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14 September 2017

Yongxiang Xia

2

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14 September 2017

Jun Li

3

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14 September 2017

Lei Deng

4

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14 September 2017

Liang Zhao

5

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14 September 2017

Jian Shi

6

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14 September 2017

Xuehao Wang

7

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14 September 2017

Beicheng Sun

8

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14 September 2017

language of work or name

English

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publication date

1 March 2010

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International Journal of Cancer

14 September 2017

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14 September 2017

126

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14 September 2017

5

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14 September 2017

1263-1274

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IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

14 September 2017

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Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis

21 January 2018

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Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation

21 January 2018

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NF-kappaB functions as a tumour promoter in inflammation-associated cancer

21 January 2018

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Limb and skin abnormalities in mice lacking IKKalpha

21 January 2018

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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

21 January 2018

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Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin

21 January 2018

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IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development

21 January 2018

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IkappaB kinase alpha kinase activity is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells

21 January 2018

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Blocking NF-kappaB as a potential strategy to treat adult T-cell leukemia/lymphoma

21 January 2018

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Nuclear factor kappa B and hepatitis viruses

21 January 2018

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The IKK/NF-kappaB activation pathway-a target for prevention and treatment of cancer

21 January 2018

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NF-kappaB and IKK as therapeutic targets in cancer

21 January 2018

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KINK-1, a novel small-molecule inhibitor of IKKbeta, and the susceptibility of melanoma cells to antitumoral treatment

21 January 2018

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RANK ligand inhibition plus docetaxel improves survival and reduces tumor burden in a murine model of prostate cancer bone metastasis

21 January 2018

1 reference

Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference

21 January 2018

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Therapeutic expression of the platelet-specific integrin, alphaIIbbeta3, in a murine model for Glanzmann thrombasthenia.

21 January 2018

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The minimal set of genetic alterations required for conversion of primary human fibroblasts to cancer cells in the subrenal capsule assay

21 January 2018

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RANKL acts directly on RANK-expressing prostate tumor cells and mediates migration and expression of tumor metastasis genes

21 January 2018

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Inhibition of RANKL blocks skeletal tumor progression and improves survival in a mouse model of breast cancer bone metastasis

21 January 2018

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Maspin and tumor metastasis

21 January 2018

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RANKL inhibition is an effective adjuvant for docetaxel in a prostate cancer bone metastases model

21 January 2018

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Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

21 January 2018

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Underexpression of transcriptional regulators is common in metastatic breast cancer cells overexpressing Bcl-xL.

21 January 2018

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Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage

21 January 2018

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Expression and role of Bcl-xL in human hepatocellular carcinomas

21 January 2018

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Elevated NF-kappaB responses and FLIP levels in leukemic but not normal lymphocytes: reduction by salicylate allows TNF-induced apoptosis

21 January 2018

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The TRAF family of signal transducers mediates NF-kappaB activation by the TRANCE receptor

21 January 2018

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Receptor activator of NF-kappaB recruits multiple TRAF family adaptors and activates c-Jun N-terminal kinase

21 January 2018

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Characterization of the intracellular domain of receptor activator of NF-kappaB (RANK). Interaction with tumor necrosis factor receptor-associated factors and activation of NF-kappab and c-Jun N-terminal kinase

21 January 2018

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The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-kappaB, a member of the TNFR superfamily

21 January 2018

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Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells

21 January 2018

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Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells

21 January 2018

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Maspin sensitizes breast carcinoma cells to induced apoptosis

21 January 2018

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Tumour-stroma interactions in colorectal cancer: converging on beta-catenin activation and cancer stemness

21 January 2018

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The tumour microenvironment as a target for chemoprevention.

21 January 2018

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NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2.

21 January 2018

1 reference

Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.24854

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14 September 2017

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