(Q39805402)

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Fluid shear stress activation of egr-1 transcription in cultured human endothelial and epithelial cells is mediated via the extracellular signal-related kinase 1/2 mitogen-activated protein kinase pathway

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Fluid shear stress activation of egr-1 transcription in cultured human endothelial and epithelial cells is mediated via the extracellular signal-related kinase 1/2 mitogen-activated protein kinase pathway (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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author name string

J L Schwachtgen

1

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

P Houston

2

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

C Campbell

3

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

V Sukhatme

4

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

M Braddock

5

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

language of work or name

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publication date

1 June 1998

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

101

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

11

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

2540-2549

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Expression of the bumetanide-sensitive Na-K-Cl cotransporter BSC2 is differentially regulated by fluid mechanical and inflammatory cytokine stimuli in vascular endothelium

1 reference

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Biomechanical activation: an emerging paradigm in endothelial adhesion biology

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Shear stress induction of the tissue factor gene

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Mitogen-activated protein kinase (ERK1/2) activation by shear stress and adhesion in endothelial cells. Essential role for a herbimycin-sensitive kinase

1 reference

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The Ras-JNK pathway is involved in shear-induced gene expression

1 reference

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Urea-inducible Egr-1 transcription in renal inner medullary collecting duct (mIMCD3) cells is mediated by extracellular signal-regulated kinase activation

1 reference

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Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear str

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Urea inducibility of egr-1 in murine inner medullary collecting duct cells is mediated by the serum response element and adjacent Ets motifs

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Role of EGR1 in regulation of stimulus-dependent CD44 transcription in B lymphocytes

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Transcriptional regulation of the tissue factor gene in human epithelial cells is mediated by Sp1 and EGR-1.

1 reference

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Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element.

1 reference

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PDGF-induced Egr-1 expression in rat mesangial cells is mediated through upstream serum response elements

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Stimulation of transcription factors NF kappa B and AP1 in endothelial cells subjected to shear stress

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A ternary complex factor-dependent mechanism mediates induction of egr-1 through selective serum response elements following antigen receptor cross-linking in B lymphocytes

1 reference

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22 September 2017

Early growth response protein 1 (Egr-1): prototype of a zinc-finger family of transcription factors.

1 reference

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22 September 2017

The cis-acting phorbol ester "12-O-tetradecanoylphorbol 13-acetate"-responsive element is involved in shear stress-induced monocyte chemotactic protein 1 gene expression

1 reference

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22 September 2017

Nuclear factor-kappa B interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress.

1 reference

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22 September 2017

Shear stress and cyclic strain modulation of gene expression in vascular endothelial cells.

1 reference

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22 September 2017

Transcriptional activation of egr-1 by granulocyte-macrophage colony-stimulating factor but not interleukin 3 requires phosphorylation of cAMP response element-binding protein (CREB) on serine 133

1 reference

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Hypercholesterolemia and endothelial dysfunction

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Comparative analysis of the ternary complex factors Elk-1, SAP-1a and SAP-2 (ERP/NET)

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22 September 2017

Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells

1 reference

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Pulsatile flow and atherosclerosis in the human carotid bifurcation. Positive correlation between plaque location and low oscillating shear stress

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Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc

1 reference

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A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

1 reference

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Transcriptional activation and repression by Fos are independent functions: the C terminus represses immediate-early gene expression via CArG elements

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v-Src activates mitogen-responsive transcription factor Egr-1 via serum response elements

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v-Fps-responsiveness in the Egr-1 promoter is mediated by serum response elements

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Ternary complex factors: growth factor regulated transcriptional activators

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Characterization of cis-acting sequences and trans-acting signals regulating early growth response 1 and c-fos promoters through the granulocyte-macrophage colony-stimulating factor receptor in BA/F3 cells.

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Role of integrins in cellular responses to mechanical stress and adhesion

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15 June 2018

Inducible expression of Egr-1-dependent genes. A paradigm of transcriptional activation in vascular endothelium

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Hemodynamics, endothelial gene expression, and atherogenesis.

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Differential effect of shear stress on extracellular signal-regulated kinase and N-terminal Jun kinase in endothelial cells. Gi2- and Gbeta/gamma-dependent signaling pathways

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Fluid flow rapidly activates G proteins in human endothelial cells. Involvement of G proteins in mechanochemical signal transduction

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Mechanism of endothelial cell shape change and cytoskeletal remodeling in response to fluid shear stress.

1 reference

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15 June 2018

Multiple cis-elements mediate shear stress-induced gene expression.

1 reference

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15 June 2018

Urea induces Egr-1 and c-fos expression in renal epithelial cells

1 reference

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5' upstream sequence and genomic structure of the human primary response gene, EGR-1/TIS8.

1 reference

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Regulation of Egr-1 (Zfp-6) and c-fos expression in differentiating embryonal carcinoma cells

1 reference

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A sensitive method for the detection of beta-galactosidase in transfected mammalian cells

1 reference

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Transcriptional repression mediated by the WT1 Wilms tumor gene product

1 reference

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15 June 2018

Evidence that activation of the Egr-1 promoter by v-Raf involves serum response elements

1 reference

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Cytokines suppress the shear stress-stimulated release of vasoactive peptides from human endothelial cells.

1 reference

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Detection and characterization of cellular EGR-1 binding to its recognition site

1 reference

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Egr-1 is activated in endothelial cells exposed to fluid shear stress and interacts with a novel shear-stress-response element in the PDGF A-chain promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shear stress induces changes in the morphology and cytoskeleton organisation of arterial endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of human vascular endothelial stress fibres by fluid shear stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterisation of the egr-1 gene product as an inducible, short-lived, nuclear phosphoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

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based on heuristic

inferred from PubMed ID database lookup

Lack of hemodynamic forces triggers apoptosis in vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimized assays for quantifying transient expressions of co-transfected beta-galactosidase and CAT reporter genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium mediates expression of stress-response genes in prostaglandin A2-induced growth arrest

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemodynamic-force-induced difference of interendothelial junctional complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oscillatory shear stress and hydrostatic pressure modulate cell-matrix attachment proteins in cultured endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shear activated channels in cell-attached patches of cultured bovine aortic endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shear stress activates cytosolic phospholipase A2 (cPLA2) and MAP kinase in human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

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based on heuristic

inferred from PubMed ID database lookup

Egr-1-induced endothelial gene expression: a common theme in vascular injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

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based on heuristic

inferred from PubMed ID database lookup

Protein kinases as mediators of fluid shear stress stimulated signal transduction in endothelial cells: a hypothesis for calcium-dependent and calcium-independent events activated by flow

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of endothelial cell gene expression by flow

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MAP kinase activation by flow in endothelial cells. Role of beta 1 integrins and tyrosine kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential display and cloning of shear stress-responsive messenger RNAs in human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluid flow inhibits endothelial adhesiveness. Nitric oxide and transcriptional regulation of VCAM-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shear stress inhibits apoptosis of human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9616225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI1404

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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