(Q39806215)

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Three Epstein-Barr virus latency proteins independently promote genomic instability by inducing DNA damage, inhibiting DNA repair and inactivating cell cycle checkpoints

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scholarly article

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Europe PubMed Central

PubMed publication ID

14 September 2017

Three Epstein-Barr virus latency proteins independently promote genomic instability by inducing DNA damage, inhibiting DNA repair and inactivating cell cycle checkpoints (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

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Epstein–Barr virus

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3

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Europe PubMed Central

PubMed publication ID

14 September 2017

author name string

B Gruhne

1

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

R Sompallae

2

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

language of work or name

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publication date

31 August 2009

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

28

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Europe PubMed Central

PubMed publication ID

14 September 2017

45

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

3997-4008

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Structural and mechanical control of mitotic progression

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

21 January 2018

Effect of the EBNA-2 gene on the surface antigen phenotype of transfected EBV-negative B-lymphoma lines

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

The ATM/p53 pathway is commonly targeted for inactivation in squamous cell carcinoma of the head and neck (SCCHN) by multiple molecular mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Down-regulation of ATM protein in HRS cells of nodular sclerosis Hodgkin's lymphoma in children occurs in the absence of ATM gene inactivation.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

The ATM tumour suppressor gene is down-regulated in EBV-associated nasopharyngeal carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Reactive oxygen species are downstream products of TRAF-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Epstein-Barr virus latent membrane protein 1 represses DNA repair through the PI3K/Akt/FOXO3a pathway in human epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

The ATM/ATR signaling effector Chk2 is targeted by Epstein-Barr virus nuclear antigen 3C to release the G2/M cell cycle block

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Expression of the Epstein-Barr virus (EBV)-encoded membrane antigen (LMP) increases the stimulatory capacity of EBV-negative B lymphoma lines in allogeneic mixed lymphocyte cultures

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Cryptic deletion involving the ATM locus at 11q22.3 approximately q23.1 in B-cell chronic lymphocytic leukemia and related disorders

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

The late lytic LMP-1 protein of Epstein-Barr virus can negatively regulate LMP-1 signaling

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Cytostatic effect of Epstein-Barr virus latent membrane protein-1 analyzed using tetracycline-regulated expression in B cell lines

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

BubR1 is required for a sustained mitotic spindle checkpoint arrest in human cancer cells treated with tubulin-targeting pyrrolo-1,5-benzoxazepines.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

The Epstein-Barr virus nuclear antigen-1 promotes genomic instability via induction of reactive oxygen species.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Real-time RT-PCR normalisation; strategies and considerations.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

DNA damage checkpoint control in cells exposed to ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Epstein-Barr virus promotes genomic instability in Burkitt's lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Epstein-Barr virus nuclear antigen 1 activates transcription from episomal but not integrated DNA and does not alter lymphocyte growth

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Epstein-Barr virus-associated Burkitt lymphomagenesis selects for downregulation of the nuclear antigen EBNA2.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Three restricted forms of Epstein-Barr virus latency counteracting apoptosis in c-myc-expressing Burkitt lymphoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Epstein-Barr virus nuclear antigen 3C regulates cyclin A/p27 complexes and enhances cyclin A-dependent kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Epstein-Barr virus latent antigen 3C can mediate the degradation of the retinoblastoma protein through an SCF cellular ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Expression of the Epstein-Barr virus latent membrane protein 1 induces B cell lymphoma in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Epstein-barr virus-induced resistance to drugs that activate the mitotic spindle assembly checkpoint in Burkitt's lymphoma cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Epstein-Barr virus latent membrane protein 1 represses p53-mediated DNA repair and transcriptional activity.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Epstein-Barr virus latent membrane protein 1 induces micronucleus formation, represses DNA repair and enhances sensitivity to DNA-damaging agents in human epithelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Epstein-Barr virus nuclear antigen 2 disrupts mitotic checkpoint and causes chromosomal instability

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Use of the intracellular fluorescent dye CFSE to monitor lymphocyte migration and proliferation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Identification of virus-encoded microRNAs

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Colonic tumorigenesis in BubR1+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Epstein-Barr virus nuclear antigen 3C augments Mdm2-mediated p53 ubiquitination and degradation by deubiquitinating Mdm2.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Redefining the Epstein-Barr virus-encoded nuclear antigen EBNA-1 gene promoter and transcription initiation site in group I Burkitt lymphoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Epstein-Barr nuclear antigen 1 contributes to nasopharyngeal carcinoma through disruption of PML nuclear bodies

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Persistent Epstein-Barr virus infection associated with monosomy 7 or chromosome 3 abnormality in childhood myeloproliferative disorders

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Epstein-Barr virus gene expression in nasopharyngeal carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Epstein-Barr virus: 40 years on

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

31 March 2020

Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.258

7 January 2021

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10.1038/ONC.2009.258

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

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