(Q39814313)

14 September 2017

title

The HIF1alpha-inducible pro-cell death gene BNIP3 is a novel target of SIM2s repression through cross-talk on the hypoxia response element (English)

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14 September 2017

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hypoxia response element

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A L Farrall

1

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14 September 2017

M L Whitelaw

series ordinal

2

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14 September 2017

language of work or name

English

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publication date

10 August 2009

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14 September 2017

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14 September 2017

volume

28

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14 September 2017

issue

41

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14 September 2017

page(s)

3671-3680

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https://scigraph.springernature.com/pub.10.1038/onc.2009.228

14 September 2017

exact match

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cites work

Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

How to interpret LC3 immunoblotting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

The murine Sim-2 gene product inhibits transcription by active repression and functional interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Upregulation of BNIP3 by 5-aza-2'-deoxycytidine sensitizes pancreatic cancer cells to hypoxia-mediated cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Intrinsic chemoresistance to gemcitabine is associated with decreased expression of BNIP3 in pancreatic cancer

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.228

Inhibition of Single Minded 2 gene expression mediates tumor-selective apoptosis and differentiation in human colon cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Selective silencing of the hypoxia-inducible factor 1 target gene BNIP3 by histone deacetylation and methylation in colorectal cancer

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.228

Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

The role of Bcl-2 family member BNIP3 in cell death and disease: NIPping at the heels of cell death.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Differences in gene expression in prostate cancer, normal appearing prostate tissue adjacent to cancer and prostate tissue from cancer free organ donors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Identification of Down's syndrome critical locus gene SIM2-s as a drug therapy target for solid tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Down's syndrome-associated Single Minded 2 gene as a pancreatic cancer drug therapy target

31 March 2020

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Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells

31 March 2020

1 reference

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Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Sim2 mutants have developmental defects not overlapping with those of Sim1 mutants

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Increased expression of SIM2-s protein is a novel marker of aggressive prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Effect of combined therapy with low-dose 5-aza-2'-deoxycytidine and irinotecan on colon cancer cell line HCT-15.

31 March 2020

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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

31 March 2020

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The mammalian basic helix-loop-helix/PAS family of transcriptional regulators

31 March 2020

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Inhibition of breast cancer growth and invasion by single-minded 2s.

31 March 2020

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Loss of singleminded-2s in the mouse mammary gland induces an epithelial-mesenchymal transition associated with up-regulation of slug and matrix metalloprotease 2.

31 March 2020

1 reference

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Reevaluation of the PPAR-β/δ Ligand Binding Domain Model Reveals Why It Exhibits the Activated Form

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

S100A4 contributes to the suppression of BNIP3 expression, chemoresistance, and inhibition of apoptosis in pancreatic cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Self-eating and self-killing: crosstalk between autophagy and apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

The role of the hypoxia-inducible BH3-only proteins BNIP3 and BNIP3L in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Differential transcriptional regulation by mouse single-minded 2s.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Two murine homologs of the Drosophila single-minded protein that interact with the mouse aryl hydrocarbon receptor nuclear translocator protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Hypoxia-activated autophagy accelerates degradation of SQSTM1/p62

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Craniofacial abnormalities resulting from targeted disruption of the murine Sim2 gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Large-scale analysis of the human and mouse transcriptomes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

The bHLH/Per-Arnt-Sim transcription factor SIM2 regulates muscle transcript myomesin2 via a novel, non-canonical E-box sequence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Differential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

Tumor hypoxia and cancer progression.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.228

31 March 2020

Identifiers

DOI

10.1038/ONC.2009.228

1 reference

14 September 2017

1 reference