(Q39820496)

English

Inhibition of epithelial to mesenchymal transition in metastatic prostate cancer cells by the novel proteasome inhibitor, NPI-0052: pivotal roles of Snail repression and RKIP induction

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scholarly article

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Europe PubMed Central

PubMed publication ID

14 September 2017

Inhibition of epithelial to mesenchymal transition in metastatic prostate cancer cells by the novel proteasome inhibitor, NPI-0052: pivotal roles of Snail repression and RKIP induction (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

prostate cancer

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based on heuristic

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author name string

S Baritaki

1

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

A Chapman

2

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

K Yeung

3

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

D A Spandidos

4

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

M Palladino

5

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

B Bonavida

6

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Europe PubMed Central

PubMed publication ID

14 September 2017

language of work or name

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publication date

27 July 2009

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Europe PubMed Central

PubMed publication ID

14 September 2017

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Europe PubMed Central

PubMed publication ID

14 September 2017

28

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Europe PubMed Central

PubMed publication ID

14 September 2017

40

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

3573-3585

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

https://scigraph.springernature.com/pub.10.1038/onc.2009.214

0 references

Regulation of tumor cell sensitivity to TRAIL-induced apoptosis by the metastatic suppressor Raf kinase inhibitor protein via Yin Yang 1 inhibition and death receptor 5 up-regulation.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

21 January 2018

Inhibition of Yin Yang 1-dependent repressor activity of DR5 transcription and expression by the novel proteasome inhibitor NPI-0052 contributes to its TRAIL-enhanced apoptosis in cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

21 January 2018

Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

21 January 2018

Salinosporamide A (NPI-0052) potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through down-modulation of NF-kappaB regulated gene products

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Snail is a repressor of RKIP transcription in metastatic prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Correlation of Snail expression with histological grade and lymph node status in breast carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

RKIP sensitizes prostate and breast cancer cells to drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

A novel proteasome inhibitor NPI-0052 as an anticancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Combination of proteasome inhibitors bortezomib and NPI-0052 trigger in vivo synergistic cytotoxicity in multiple myeloma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

NPI-0052 enhances tumoricidal response to conventional cancer therapy in a colon cancer model.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Unraveling signalling cascades for the Snail family of transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Phosphorylation regulates the subcellular location and activity of the snail transcriptional repressor

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Expression of E-cadherin transcriptional regulators in ovarian carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Discovery and development of the anticancer agent salinosporamide A (NPI-0052).

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Metastasis suppressor gene Raf kinase inhibitor protein (RKIP) is a novel prognostic marker in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Effects of raf kinase inhibitor protein expression on suppression of prostate cancer metastasis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Reduction of Raf-1 kinase inhibitor protein expression correlates with breast cancer metastasis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

NF-kappaB activation in development and progression of cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Inverse correlation between E-cadherin and Snail expression in hepatocellular carcinoma cell lines in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Activation of NF-kappaB by Akt upregulates Snail expression and induces epithelium mesenchyme transition

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Reversal of resistance to cytotoxic cancer therapies: DHMEQ as a chemo-sensitizing and immuno-sensitizing agent

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Snail-related transcriptional repressors are required in Xenopus for both the induction of the neural crest and its subsequent migration

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

NPI-0052, a novel proteasome inhibitor, induces caspase-8 and ROS-dependent apoptosis alone and in combination with HDAC inhibitors in leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Loss of Raf-1 Kinase Inhibitor Protein Expression Is Associated With Tumor Progression and Metastasis in Colorectal Cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

The snail superfamily of zinc-finger transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Raf-1 kinase inhibitor protein: structure, function, regulation of cell signaling, and pivotal role in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Snail silencing effectively suppresses tumour growth and invasiveness.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Detection, clinical relevance and specific biological properties of disseminating tumour cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Dual targeting of the proteasome regulates survival and homing in Waldenstrom macroglobulinemia

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

The proteasome inhibitor NPI-0052 is a more effective inducer of apoptosis than bortezomib in lymphocytes from patients with chronic lymphocytic leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Mechanisms, mechanics and function of epithelial-mesenchymal transitions in early development

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Proteasome inhibition activates epidermal growth factor receptor (EGFR) and EGFR-independent mitogenic kinase signaling pathways in pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Tumor metastasis: mechanistic insights and clinical challenges

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

The potential of proteasome inhibitors in cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Complex networks orchestrate epithelial-mesenchymal transitions

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Overexpression of NBS1 induces epithelial-mesenchymal transition and co-expression of NBS1 and Snail predicts metastasis of head and neck cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Reverse correlation of E-cadherin and snail expression in oral squamous cell carcinoma cells in vitro.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.214

31 March 2020

Identifiers

10.1038/ONC.2009.214

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

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