(Q39820505)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19633683%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

The pyridinylfuranopyrimidine inhibitor, PI-103, chemosensitizes glioblastoma cells for apoptosis by inhibiting DNA repair (English)

1 reference

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3 February 2020

0 references

1 reference

9

1 reference

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3 February 2020

Mike-Andrew Westhoff

1

1 reference

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3 February 2020

Adriana Eramo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19633683%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Klaus-Michael Debatin

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19633683%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

author name string

J A Kandenwein

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19633683%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

S Karl

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19633683%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

S H K Vellanki

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19633683%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

V Braun

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19633683%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

G Antoniadis

7

1 reference

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3 February 2020

language of work or name

English

0 references

publication date

27 July 2009

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3 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19633683%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

volume

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19633683%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

issue

40

1 reference

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3 February 2020

page(s)

3586-3596

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https://scigraph.springernature.com/pub.10.1038/onc.2009.215

3 February 2020

exact match

0 references

cites work

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Cancer stem cells and chemoradiation resistance

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PI3K/PTEN signaling in tumorigenesis and angiogenesis

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

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PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival

31 March 2020

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The in vivo comet assay: use and status in genotoxicity testing

31 March 2020

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

31 March 2020

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Novel therapies for malignant gliomas

31 March 2020

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The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas

31 March 2020

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Characterization of structurally distinct, isoform-selective phosphoinositide 3'-kinase inhibitors in combination with radiation in the treatment of glioblastoma

31 March 2020

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Mechanisms of human DNA repair: an update

31 March 2020

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Molecular predictors in glioblastoma: toward personalized therapy

31 March 2020

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31 March 2020

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Chemotherapy resistance of glioblastoma stem cells

31 March 2020

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A dual phosphoinositide-3-kinase alpha/mTOR inhibitor cooperates with blockade of epidermal growth factor receptor in PTEN-mutant glioma

31 March 2020

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A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

31 March 2020

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Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase

31 March 2020

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31 March 2020

Phosphoinositide kinases

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Sensitization for gamma-irradiation-induced apoptosis by second mitochondria-derived activator of caspase

31 March 2020

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Pegylated liposomal doxorubicin in recurrent malignant glioma: analysis of a case series

31 March 2020

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Defining the role of mTOR in cancer

31 March 2020

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Pegylated liposomal doxorubicin-efficacy in patients with recurrent high-grade glioma

31 March 2020

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Take your PIK: phosphatidylinositol 3-kinase inhibitors race through the clinic and toward cancer therapy

31 March 2020

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Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines.

31 March 2020

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Sensing and repairing DNA double-strand breaks

31 March 2020

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Inhibition of phosphatidylinositol-3-OH kinase/Akt signaling impairs DNA repair in glioblastoma cells following ionizing radiation

31 March 2020

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Differential regulation of DNA repair protein Rad51 in human tumour cell lines exposed to doxorubicin

31 March 2020

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31 March 2020

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31 March 2020

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Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- and drug-induced apoptosis

31 March 2020

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31 March 2020

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31 March 2020

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Class I PI3 kinase inhibition by the pyridinylfuranopyrimidine inhibitor PI-103 enhances tumor radiosensitivity.

31 March 2020

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31 March 2020

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31 March 2020

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