(Q39821280)

14 September 2017

title

Inhibition of protein kinase CK2 expression and activity blocks tumor cell growth (English)

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14 September 2017

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Dan Zhu

1

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14 September 2017

Jennifer Hensel

2

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14 September 2017

Robert Hilgraf

3

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14 September 2017

Mahan Abbasian

4

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14 September 2017

Owen Pornillos

5

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14 September 2017

Gordafaried Deyanat-Yazdi

6

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14 September 2017

Xuequn Helen Hua

7

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14 September 2017

Sarah Cox

8

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14 September 2017

language of work or name

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21 July 2009

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Molecular and Cellular Biochemistry

14 September 2017

published in

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14 September 2017

volume

333

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14 September 2017

issue

1-2

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14 September 2017

page(s)

159-167

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https://scigraph.springernature.com/pub.10.1007/s11010-009-0216-0

14 September 2017

exact match

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cites work

The multiple personalities of the regulatory subunit of protein kinase CK2: CK2 dependent and CK2 independent roles reveal a secret identity for CK2beta

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11010-009-0216-0

Features and potentials of ATP-site directed CK2 inhibitors

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11010-009-0216-0

The selectivity of inhibitors of protein kinase CK2: an update

21 January 2018

1 reference

12 December 2020

Induction of apoptosis by antisense CK2 in human prostate cancer xenograft model.

1 reference

12 December 2020

Casein kinase 2: an 'eminence grise' in cellular regulation?

1 reference

12 December 2020

CK2 inhibits apoptosis and changes its cellular localization following ionizing radiation

1 reference

12 December 2020

Casein kinase 2 regulates both apoptosis and the cell cycle following DNA damage induced by 6-thioguanine

1 reference

12 December 2020

Casein kinase I and II--multipotential serine protein kinases: structure, function, and regulation.

1 reference

12 December 2020

Inducible expression of the regulatory protein kinase CK2beta subunit: incorporation into complexes with catalytic CK2 subunits and re-examination of the effects of CK2beta on cell proliferation

1 reference

12 December 2020

Structure-based design and synthesis of novel macrocyclic pyrazolo[1,5-a] [1,3,5]triazine compounds as potent inhibitors of protein kinase CK2 and their anticancer activities

1 reference

12 December 2020

CK2 as a positive regulator of Wnt signalling and tumourigenesis

1 reference

12 December 2020

The alpha catalytic subunit of protein kinase CK2 is required for mouse embryonic development

1 reference

12 December 2020

Expression of the casein kinase 2 subunits in Chinese hamster ovary and 3T3 L1 cells provides information on the role of the enzyme in cell proliferation and the cell cycle

1 reference

12 December 2020

Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA)

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12 December 2020

Targeting CK2 for cancer therapy

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12 December 2020

The enzymatic phosphorylation of proteins

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12 December 2020

Protein kinase CK2 in health and disease: Cellular functions of protein kinase CK2: a dynamic affair.

1 reference

12 December 2020

Isolation and characterization of recombinant human casein kinase II subunits alpha and beta from bacteria.

1 reference

12 December 2020

2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2.

1 reference

12 December 2020

Inducible expression of protein kinase CK2 in mammalian cells. Evidence for functional specialization of CK2 isoforms.

1 reference

12 December 2020

Enhanced casein kinase II activity in human tumour cell cultures

1 reference

12 December 2020

The 'regulatory' beta-subunit of protein kinase CK2 negatively influences p53-mediated allosteric effects on Chk2 activation

1 reference

12 December 2020

Protein kinase CK2: structure, regulation and role in cellular decisions of life and death

1 reference

12 December 2020

Recent kinase and kinase inhibitor X-ray structures: mechanisms of inhibition and selectivity insights

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12 December 2020

Characterization of the phosphotransferase domain of casein kinase II by site-directed mutagenesis and expression in Escherichia coli

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12 December 2020

Protein kinase CK2 as a druggable target

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12 December 2020

Coexpression of both alpha and beta subunits is required for assembly of regulated casein kinase II.

1 reference

12 December 2020

Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole

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12 December 2020

Regulation of casein kinase-2 (CK2) activity by inositol phosphates

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12 December 2020

Systemic administration of a peptide that impairs the protein kinase (CK2) phosphorylation reduces solid tumor growth in mice.

1 reference

12 December 2020

Determination of mRNA, and protein levels of p53, MDM2 and protein kinase CK2 subunits in F9 cells after treatment with the apoptosis-inducing drugs cisplatin and carboplatin.

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12 December 2020

Halogenated benzimidazoles and benzotriazoles as inhibitors of the NTPase/helicase activities of hepatitis C and related viruses

1 reference

12 December 2020

Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study

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12 December 2020

Protein kinase CK2 promotes aberrant activation of nuclear factor-kappaB, transformed phenotype, and survival of breast cancer cells.

1 reference

12 December 2020

The shape of things to come: an emerging role for protein kinase CK2 in the regulation of cell morphology and the cytoskeleton

1 reference

12 December 2020

A CK2-dependent mechanism for degradation of the PML tumor suppressor

1 reference

12 December 2020

Protein kinase CK2--a key suppressor of apoptosis

1 reference

12 December 2020

Validation of protein kinase CK2 as oncological target.

1 reference

12 December 2020

Protein kinase CK2 in human diseases.

1 reference

12 December 2020

New inhibitors of protein kinase CK2, analogues of benzimidazole and benzotriazole

1 reference

12 December 2020

A role for protein kinase CK2 in cell proliferation: evidence using a kinase-inactive mutant of CK2 catalytic subunit alpha.

1 reference

12 December 2020

Disruption of the regulatory beta subunit of protein kinase CK2 in mice leads to a cell-autonomous defect and early embryonic lethality

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12 December 2020

Protein kinase CK2: signaling and tumorigenesis in the mammary gland

1 reference

12 December 2020

CK2 Is a C-Terminal IκB Kinase Responsible for NF-κB Activation during the UV Response

1 reference

12 December 2020

A potential role of nuclear matrix-associated protein kinase CK2 in protection against drug-induced apoptosis in cancer cells

1 reference

12 December 2020

Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis

1 reference

12 December 2020

Casein kinase II (CK2) enhances death-inducing signaling complex (DISC) activity in TRAIL-induced apoptosis in human colon carcinoma cell lines.

1 reference

12 December 2020

Resorufin: a lead for a new protein kinase CK2 inhibitor

1 reference

12 December 2020

Tetrabromocinnamic Acid (TBCA) and Related Compounds Represent a New Class of Specific Protein Kinase CK2 Inhibitors

1 reference

12 December 2020

Gene targeting of CK2 catalytic subunits

1 reference

12 December 2020

The CCP4 suite: programs for protein crystallography

1 reference

12 December 2020

The catalytic subunit of human protein kinase CK2 structurally deviates from its maize homologue in complex with the nucleotide competitive inhibitor emodin

1 reference

12 December 2020

Evaluating CK2 activity with the antibody specific for the CK2-phosphorylated form of a kinase-targeting cochaperone Cdc37.

1 reference

12 December 2020

Inhibition of CK2 activity by TGF-beta1 promotes IkappaB-alpha protein stabilization and apoptosis of immortalized hepatocytes

1 reference

12 December 2020

Protein kinase CK2 as regulator of cell survival: implications for cancer therapy

1 reference

12 December 2020

Recombinant human casein kinase II. A study with the complete set of subunits (alpha, alpha' and beta), site-directed autophosphorylation mutants and a bicistronically expressed holoenzyme.

1 reference

12 December 2020

Antisense oligonucleotides against protein kinase CK2-alpha inhibit growth of squamous cell carcinoma of the head and neck in vitro

1 reference

12 December 2020

Casein kinase II is elevated in solid human tumours and rapidly proliferating non-neoplastic tissue

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12 December 2020

Cell cycle dependent regulation of protein kinase CK2 signaling to the nuclear matrix

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12 December 2020

One-thousand-and-one substrates of protein kinase CK2?

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12 December 2020

Role of protein kinase CK2 in phosphorylation nucleosomal proteins in relation to transcriptional activity

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12 December 2020

TBBz but not TBBt discriminates between two molecular forms of CK2 in vivo and its implications.

1 reference

12 December 2020

A global view of CK2 function and regulation.

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12 December 2020

Protein kinase CK2: a newcomer in the 'druggable kinome'.

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12 December 2020

Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta

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12 December 2020

The protein kinase CK2 phosphorylates SNAP190 to negatively regulate SNAPC DNA binding and human U6 transcription by RNA polymerase III

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12 December 2020

10.1007/S11010-009-0216-0

Identifiers

DOI

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14 September 2017

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