(Q39823619)

14 July 2018

title

Inhibition of STAT-3 results in radiosensitization of human squamous cell carcinoma (English)

1 reference

14 July 2018

author

Christopher D. Willey

3

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14 September 2017

James A Bonner

1

1 reference

14 July 2018

Hoa Q Trummell

2

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14 July 2018

Brian A Plants

4

1 reference

14 July 2018

Kevin P Raisch

5

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14 July 2018

publication date

16 July 2009

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14 July 2018

Radiotherapy and Oncology

published in

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14 July 2018

volume

92

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14 July 2018

page(s)

339-344

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14 July 2018

issue

3

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14 July 2018

ErbB2-mediated Src and signal transducer and activator of transcription 3 activation leads to transcriptional up-regulation of p21Cip1 and chemoresistance in breast cancer cells

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1 reference

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Small molecular inhibitors of p-STAT3: novel agents for treatment of primary and metastatic CNS cancers

15 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

STAT3 activation in pressure-overloaded feline myocardium: role for integrins and the tyrosine kinase BMX

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

Combined targeting of epidermal growth factor receptor, signal transducer and activator of transcription-3, and Bcl-X(L) enhances antitumor effects in squamous cell carcinoma of the head and neck.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

STAT3 signaling is induced by intercellular adhesion in squamous cell carcinoma cells

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

The epidermal growth factor receptor pathway: a model for targeted therapy

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

Treatment for advanced tumors: SRC reclaims center stage

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

A novel platinum compound inhibits constitutive Stat3 signaling and induces cell cycle arrest and apoptosis of malignant cells

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

Anti-EGFR-mediated radiosensitization as a result of augmented EGFR expression

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

MDM2 is a negative regulator of p21WAF1/CIP1, independent of p53.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

Epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib, and concurrent 5-fluorouracil, cisplatin and radiotherapy for patients with esophageal cancer: a phase I study

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

The interaction of epidermal growth factor and radiation in human head and neck squamous cell carcinoma cell lines with vastly different radiosensitivities

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5906031

Rationally designed inhibitors identify STAT3 N-domain as a promising anticancer drug target

20 August 2018

1 reference

12 December 2020

Combined modality therapy of A431 human epidermoid cancer using anti-EGFr antibody C225 and radiation

1 reference

12 December 2020

Mean inactivation dose: a useful concept for intercomparison of human cell survival curves

1 reference

12 December 2020

Targeting STAT3 in cancer: how successful are we?

1 reference

12 December 2020

Enhanced apoptosis with combination C225/radiation treatment serves as the impetus for clinical investigation in head and neck cancers

1 reference

12 December 2020

10.1016/J.RADONC.2009.06.022

Identifiers

DOI

1 reference

14 July 2018

PMCID

5906031

1 reference

14 July 2018

PubMed ID

19616333

1 reference

14 July 2018