(Q39845007)

15 September 2017

title

Simultaneous loss of the DLC1 and PTEN tumor suppressors enhances breast cancer cell migration (English)

1 reference

15 September 2017

Johanna Heering

1

1 reference

15 September 2017

Patrik Erlmann

series ordinal

2

1 reference

15 September 2017

Monilola A Olayioye

series ordinal

3

1 reference

15 September 2017

language of work or name

English

0 references

publication date

29 May 2009

1 reference

Experimental Cell Research

15 September 2017

published in

1 reference

15 September 2017

volume

315

1 reference

15 September 2017

issue

15

1 reference

15 September 2017

page(s)

2505-2514

1 reference

Tenets of PTEN tumor suppression

15 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Tumours and tremors: how PTEN regulation underlies both

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Analysis of the 10q23 chromosomal region and the PTEN gene in human sporadic breast carcinoma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Allelic loss of the PTEN region (10q23) in breast carcinomas of poor pathophenotype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Loss of expression of the PTEN gene protein product is associated with poor outcome in breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Pten is essential for embryonic development and tumour suppression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

PTEN and myotubularin: novel phosphoinositide phosphatases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

AKT/PKB signaling: navigating downstream

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

DLC-1: a Rho GTPase-activating protein and tumour suppressor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

DLC1: a significant GAP in the cancer genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

DLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Rho GTPases: biochemistry and biology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Deleted in liver cancer 1 controls cell migration through a Dia1-dependent signaling pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Cell migration: integrating signals from front to back

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

DLC1 interacts with 14-3-3 proteins to inhibit RhoGAP activity and block nucleocytoplasmic shuttling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

The regulation of cell motility and chemotaxis by phospholipid signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

The regulation of cell migration by PTEN.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Morphological changes and detachment of adherent cells induced by p122, a GTPase-activating protein for Rho.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Regulation of PTEN function as a PIP3 gatekeeper through membrane interaction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Regulation of PTEN activity by its carboxyl-terminal autoinhibitory domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Deficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Phosphatase and tensin homologue deleted on chromosome 10 deficiency accelerates tumor induction in a mouse model of ErbB-2 mammary tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Mutations in the focal adhesion targeting region of deleted in liver cancer-1 attenuate their expression and function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

DLC-1 gene inhibits human breast cancer cell growth and in vivo tumorigenicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Tumor suppressor PTEN mediates sensing of chemoattractant gradients.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

PTEN plays a role in the suppression of lateral pseudopod formation during Dictyostelium motility and chemotaxis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

PTEN regulates motility but not directionality during leukocyte chemotaxis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Regulation of cell migration by the C2 domain of the tumor suppressor PTEN.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Interaction of deleted in liver cancer 1 with tensin2 in caveolae and implications in tumor suppression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Oncogenic inhibition by a deleted in liver cancer gene requires cooperation between tensin binding and Rho-specific GTPase-activating protein activities

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

SAM domains: uniform structure, diversity of function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

Regulation of PTEN by Rho small GTPases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.05.022

10.1016/J.YEXCR.2009.05.022

7 January 2021

Identifiers

DOI

1 reference

15 September 2017

1 reference