(Q39848702)

15 September 2017

Palmitoylation regulates the intracellular trafficking and stability of c-Met (English)

1 reference

15 September 2017

David T Coleman

1

1 reference

15 September 2017

Alana L Gray

series ordinal

2

1 reference

15 September 2017

Steven J Kridel

series ordinal

3

1 reference

15 September 2017

James A Cardelli

series ordinal

4

1 reference

15 September 2017

language of work or name

English

0 references

publication date

12 April 2016

1 reference

15 September 2017

1 reference

15 September 2017

7

1 reference

15 September 2017

22

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15 September 2017

32664-32677

1 reference

describes a project that uses

15 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5078042/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Intracellular activation of EGFR by fatty acid synthase dependent palmitoylation.

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Palmitoylation of amyloid precursor protein regulates amyloidogenic processing in lipid rafts

22 September 2017

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Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.

22 September 2017

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Shedding-generated Met receptor fragments can be routed to either the proteasomal or the lysosomal degradation pathway

22 September 2017

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MET: a promising anticancer therapeutic target

22 September 2017

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Palmitoylation regulates 17β-estradiol-induced estrogen receptor-α degradation and transcriptional activity

22 September 2017

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Targeting MET in cancer: rationale and progress

22 September 2017

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Lipid-dependent protein sorting at the trans-Golgi network

22 September 2017

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Met degradation: more than one stone to shoot a receptor down

22 September 2017

1 reference

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A palmitoylation switch mechanism regulates Rac1 function and membrane organization.

22 September 2017

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Chemical biology of lipidated proteins

22 September 2017

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Distinct involvement of the Gab1 and Grb2 adaptor proteins in signal transduction by the related receptor tyrosine kinases RON and MET.

22 September 2017

1 reference

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Membrane targeting of palmitoylated Wnt and Hedgehog revealed by chemical probes.

22 September 2017

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Bioorthogonal chemical reporters for analyzing protein lipidation and lipid trafficking

22 September 2017

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DHHC palmitoyl transferases: substrate interactions and (patho)physiology

22 September 2017

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The HGF-met signaling axis: emerging themes and targets of inhibition

22 September 2017

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MET signalling: principles and functions in development, organ regeneration and cancer

22 September 2017

1 reference

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De novo lipogenesis maintains vascular homeostasis through endothelial nitric-oxide synthase (eNOS) palmitoylation.

22 September 2017

1 reference

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Proteomic analysis of fatty-acylated proteins in mammalian cells with chemical reporters reveals S-acylation of histone H3 variants

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

The chemical toolbox for monitoring protein fatty acylation and prenylation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Dorsal ruffle microdomains potentiate Met receptor tyrosine kinase signaling and down-regulation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Inhibition of fatty acid synthase suppresses c-Met receptor kinase and induces apoptosis in diffuse large B-cell lymphoma.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.

22 September 2017

1 reference

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The role of MET activation in determining the sensitivity to epidermal growth factor receptor tyrosine kinase inhibitors

22 September 2017

1 reference

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Segregation of sphingolipids and sterols during formation of secretory vesicles at the trans-Golgi network

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Palmitoyl acyltransferase assays and inhibitors (Review).

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Inhibition of fatty acid synthase by luteolin post-transcriptionally down-regulates c-Met expression independent of proteosomal/lysosomal degradation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Cohort study of fatty acid synthase expression and patient survival in colon cancer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of beta-catenin in prostate cancer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

2-Bromopalmitate and 2-(2-hydroxy-5-nitro-benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Receptor trafficking controls weak signal delivery: a strategy used by c-Met for STAT3 nuclear accumulation.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Transport and transporters in the endoplasmic reticulum

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Chemical probes for the rapid detection of Fatty-acylated proteins in Mammalian cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Trafficking and signaling by fatty-acylated and prenylated proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Gastrointestinal hormones cause rapid c-Met receptor down-regulation by a novel mechanism involving clathrin-mediated endocytosis and a lysosome-dependent mechanism

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Assays of protein palmitoylation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Ab-induced ectodomain shedding mediates hepatocyte growth factor receptor down-regulation and hampers biological activity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Met activation and receptor dimerization in cancer: a role for the Sema domain

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

c-Met signalling: spatio-temporal decisions

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

The met receptor degradation pathway: requirement for Lys48-linked polyubiquitin independent of proteasome activity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Compartmentalization of integrin α6β4 signaling in lipid rafts

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

A role for palmitoylation in the quality control, assembly and secretion of apolipoprotein B

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

c-Met: structure, functions and potential for therapeutic inhibition

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Shedding of c-Met is regulated by crosstalk between a G-protein coupled receptor and the EGF receptor and is mediated by a TIMP-3 sensitive metalloproteinase.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Palmitoylation of apolipoprotein B is required for proper intracellular sorting and transport of cholesteroyl esters and triglycerides

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Induction of epithelial tubules by growth factor HGF depends on the STAT pathway

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Fatty acid-mediated calcium sequestration within intracellular calcium pools

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Fatty acid synthase modulates intestinal barrier function through palmitoylation of mucin 2.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

GGA3 functions as a switch to promote Met receptor recycling, essential for sustained ERK and cell migration

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Scatter factor is a fibroblast-derived modulator of epithelial cell mobility

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Mechanism of met oncogene activation

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Single-cell imaging of Wnt palmitoylation by the acyltransferase porcupine.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Raft-like membranes from the trans-Golgi network and endosomal compartments.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Rho Family GTPase modification and dependence on CAAX motif-signaled posttranslational modification

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Insights into function of PSI domains from structure of the Met receptor PSI domain

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Palmitoylation of caveolin-1 at a single site (Cys-156) controls its coupling to the c-Src tyrosine kinase: targeting of dually acylated molecules (GPI-linked, transmembrane, or cytoplasmic) to caveolae effectively uncouples c-Src and caveolin-1 (TY

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Down-regulation of MET, the receptor for hepatocyte growth factor.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Inhibition of protein palmitoylation, raft localization, and T cell signaling by 2-bromopalmitate and polyunsaturated fatty acids.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078042

Identification and evolution of dual-topology membrane proteins

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27081699

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Biosynthesis of the protein encoded by the c-met proto-oncogene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27081699

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/ONCOTARGET.8706

1 reference

15 September 2017

1 reference

15 September 2017

PubMed publication ID

27081699

1 reference